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RecruitingPHASE1INTERVENTIONAL

Adoptive Cell Therapy Long-term Follow-up (LTFU) Study

This study is designed to keep an eye on the long-term health and safety of people who have previously received a special type of treatment called ADP adoptive cell therapy. It's not a study where you receive new treatment; instead, it's about checking in with you over a long period, up to 15 years after your last treatment. The main goal is to understand how people are doing in the years following this therapy and to make sure it remains safe. This is important for everyone who has had or might have this kind of treatment in the future.

At a glance

Status
Recruiting
Phase
PHASE1
Sponsor
USWM CT, LLC
Enrolment target
250
Start
09 Apr 2018
Estimated completion
01 Apr 2032

What is this study about?

Imagine you've had a special treatment called ADP adoptive cell therapy, which uses your body's own cells to fight certain diseases. This study, called the "Adoptive Cell Therapy Long-term Follow-up (LTFU) Study," is all about checking in on people who have already received this treatment. It's not about giving you new medicine or a new treatment. Instead, it's about seeing how you are doing over a long period, specifically up to 15 years after your last treatment.

The main purpose of this study is to understand the long-term effects of ADP adoptive cell therapy. When new treatments are developed, doctors need to know not just if they work, but also if they are safe for many years to come. By following people like you, researchers can gather important information that helps doctors understand the full picture of this therapy and ensure it continues to be a safe option for patients.

Think of it as a very long-term health check-up specifically for this treatment. Your participation helps medical science learn more about how to make treatments even better and safer for everyone.

Key takeaways

  • This study tracks long-term safety of a specific cell therapy.
  • It's a follow-up, not a treatment study.
  • Participants are monitored for up to 15 years.
  • Helps understand long-term effects of ADP adoptive cell therapy.
  • Your participation helps improve future treatments.

Who may be eligible?

To be part of this study, you must have already received at least one dose of the ADP adoptive cell therapy. This means you would have taken part in a previous study or received the treatment through a special managed access program.

There are no reasons that would stop you from joining this study if you meet the above requirements. The medical team will review your health history to make sure everything is in order.

Finally, you need to be able to understand what the study involves and be willing to sign a consent form to show you agree to take part.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

  1. Have I already received at least one dose of ADP adoptive cell therapy?
  2. Did I complete or withdraw from a previous study of this therapy?
  3. Did I receive this therapy through a special managed access program?
  4. Am I able to understand information about the study and sign a consent form?
Answer every question to see your result.

What does participation involve?

If you join this study, you won't be given any new medication or therapy. Instead, the study will involve regular check-ups over a long period. These check-ups are designed to monitor your health and see how you are doing after your ADP adoptive cell therapy. The exact details of what these check-ups involve, such as blood tests or health questionnaires, will be explained by the study team.

You will be followed for quite a long time, potentially up to 15 years after you received your last treatment. The study team will tell you how often you will need to attend appointments, which could be in person or over the phone. The total duration of your participation will depend on when you received your last therapy, but it could be for many years.

Potential risks and benefits

The main benefit of taking part in this study is that you'll be contributing valuable information that helps doctors and researchers learn more about the long-term safety of ADP adoptive cell therapy. This is crucial for improving treatments for future patients. Since you won't be receiving new treatment, the risks are generally low, focusing on potential inconvenience from visits or tests. You have the right to withdraw from the study at any time, for any reason, without it affecting your medical care.

Locations (24)

Some site locations are approximate. We're improving this — please verify with the trial team before travelling.
  • Emory University School of Medicine
    Verified postcode
    Atlanta, United States· Recruiting
  • ADP Investigational Site
    Verified postcode
    Baltimore, United States· Recruiting
  • National Cancer Institute - Center for Cancer Research
    Verified postcode
    Bethesda, United States· Completed
  • University of Michigan
    Verified postcode
    Ann Arbor, United States· Recruiting
  • Washington University School of Medicine in St. Louis
    Verified postcode
    St Louis, United States· Recruiting
  • Memorial Sloan Kettering Cancer Center - New York
    Verified postcode
    New York, United States· Recruiting
  • Duke University Medical Center
    Verified postcode
    Durham, United States· Recruiting
  • Oregon Health and Science University
    Verified postcode
    Portland, United States· Recruiting
  • University of Pennsylvania
    Verified postcode
    Philadelphia, United States· Recruiting
  • University of Pittsburgh Medical Center (UPMC) Hillman Cancer Center
    Verified postcode
    Pittsburgh, United States· Recruiting
  • University of Texas Southwestern Medical Center
    Verified postcode
    Dallas, United States· Recruiting
  • University of Texas MD Anderson Cancer Center
    Verified postcode
    Houston, United States· Recruiting

Common questions

What is ADP adoptive cell therapy?

It's a special treatment that uses your body's own cells, modified in a lab, to fight certain diseases.

Will I receive new treatment in this study?

No, this study is only for following up on people who have already had the treatment.

Why is this study needed?

It helps doctors understand the long-term safety and effects of the therapy over many years.

How long will I be followed?

You could be followed for up to 15 years after your last treatment.

Do I have to take part?

No, taking part is completely voluntary, and you can choose to leave at any time.

How to find out more

Investigator Study Inquiries LTFU

Always speak to your GP or specialist before deciding to take part in a study.

Interested in taking part?

Register your interest

Share your details and the research team for "Adoptive Cell Therapy Long-term Follow-up (LTFU) Study…" will contact you if you may be eligible. Always speak to your GP before agreeing to take part.

Discussion

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