Immunotherapy or Targeted Therapy With or Without Stereotactic Radiosurgery for Patients With Brain Metastases From Melanoma or Non-small Cell Lung Cancer

To join this study, you would need to have new brain tumours (metastases) that haven't been treated yet, apart from surgery. These tumours would need to have come from either melanoma or non-small cell lung cancer. You should not be experiencing severe symptoms from your brain tumours that require strong medication for more than a week.

There are also specific requirements about the number and size of your brain tumours. Generally, you can have between 1 and 10 brain tumours, and they must be a certain size to qualify. If you've had surgery to remove a brain tumour, that's usually allowed, as long as the other criteria are met. Your doctor will carefully check all these details to see if this study could be right for you.

If you join this study, you would be randomly put into one of two groups. One group would receive your standard cancer treatment (like immunotherapy or targeted therapy) plus stereotactic radiosurgery (SRS) for your brain tumours. The other group would receive only your standard cancer treatment. You would have regular check-ups, scans (like MRI scans of your brain), and tests to monitor your health and how the treatment is working. Doctors and study staff would guide you through each step. The total duration of your participation would depend on how your treatment progresses, but you would be followed up regularly.