Ongoing, recruitingHuman Pharmacology (Phase I)- OtherInterventional

A trial to evaluate the absolute bioavailability of cenerimod in healthy male participants

This research study is about a new medicine called cenerimod. It's a very early-stage trial, focusing on healthy male volunteers. The main goal is to find out exactly how much of the cenerimod swallowed ends up in the bloodstream when taken by mouth. This is important because it helps scientists understand how well the medicine is absorbed and how it moves through the body. This kind of information is crucial for developing new medicines safely and effectively. It’s part of the first steps in testing a new medicine in people, helping researchers decide if it's safe and worth studying further for specific health conditions down the line.

At a glance

Status

Ongoing, recruiting

Phase

Human Pharmacology (Phase I)- Other

Sponsor

Viatris Innovation GmbH

Enrolment target

Start

07 Nov 2025

Not applicable - healthy volunteer trial

What is this study about?

Imagine you swallow a tablet. How much of that medicine actually gets into your body to do its job? This study aims to answer exactly that question for a new medicine called cenerimod. It's a very early-stage trial, meaning it's one of the first times this medicine is being tested in people.

Researchers want to understand how much of the cenerimod is absorbed into the bloodstream when you take it by mouth. This is called 'bioavailability'. Knowing this helps scientists figure out the right dose and how often the medicine might need to be taken if it proves to be useful in the future. It’s a bit like checking how much fuel actually makes it into your car's engine rather than being lost along the way.

This kind of study is really important because it provides fundamental information about how a new medicine behaves in the human body. This basic understanding helps researchers make key decisions about whether to continue developing cenerimod for people with specific health problems, and helps them ensure any future studies are as safe and effective as possible.

Key takeaways

This is an early-stage study for a new medicine called cenerimod.
It's for healthy men, age 18 and older.
The main goal is to see how much of the medicine gets into the body.
Participation helps scientists understand new medicines better.
You will be monitored closely by medical staff.

Who may be eligible?

This study is only looking for men who are healthy and between the ages of 18 and older. There isn't an upper age limit mentioned, but participants must be adults.

Because this is a study for healthy volunteers, you shouldn't have any serious ongoing health problems. The researchers will carry out checks to make sure you are in good health before you can join.

This study is specifically designed for men. Women are not being recruited for this particular trial.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you a man?
Are you 18 years old or older?
Do you consider yourself generally healthy?
Are you willing to potentially have blood tests and body checks?

Answer every question to see your result.

What does participation involve?

The detailed plan for taking part isn't provided, but generally for this type of early study, it would involve several visits to a clinic. You would likely be given the cenerimod medicine, and doctors would take regular blood and urine samples over a period of time to see how your body handles the medicine. This might involve staying at a clinic for a few days or having multiple outpatient visits. You would be carefully monitored by medical staff throughout. The total duration of your involvement could range from a few weeks to a couple of months, including follow-up appointments.

Potential risks and benefits

The main benefit of taking part in this type of study is helping medical science learn more about new medicines. You wouldn't directly benefit from taking the medicine, as you are healthy. Potential risks could include side effects from the medicine, such as feeling unwell, or discomfort from blood tests. All efforts are made to ensure your safety. Remember, you have the right to withdraw from the study at any time, for any reason, without it affecting your medical care.

Locations (1)

Some site locations are approximate. We're improving this — please verify with the trial team before travelling.

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Unverified
Netherlands

Common questions

What is cenerimod?

Cenerimod is a new medicine being studied. This trial is designed to understand how it works in the body, not to treat any specific condition yet.

Why are only men eligible for this study?

Often, early studies are designed to test medicines in one gender first to simplify the initial data collection and reduce variables. Future studies might include women.

Will I get paid for taking part?

The information provided doesn't say if you will be paid. Clinical trials often offer reimbursement for time and travel, but you should always ask the study team directly.

What kind of tests will I have?

Though not fully detailed, you can expect blood and urine samples, and possibly other general health checks to monitor how your body responds to the medicine.

Is this medicine available to the public?

No, cenerimod is still in the early stages of research and is not available as a treatment for any condition. It is only being used for research purposes in this study.