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Enrolling by invitationNAINTERVENTIONAL

Bioavailability From Chickpea Meals in Ileostomists?

Have you ever wondered if the way your food is prepared affects how much nutrition your body actually gets? This study explores just that, focusing on plant-based foods like chickpeas. Plants have special walls around their cells that can make it harder for our bodies to digest them fully and get all the energy and good things inside. This research will compare two chickpea meals – one with intact, whole chickpeas (like in a salad) and one with broken-down chickpeas (like in a burger). We want to understand if breaking these cell walls helps your body absorb more protein, fats, carbohydrates, and beneficial plant compounds. It's especially looking at people who have had an ileostomy to get clear results on digestion.

At a glance

Status
Enrolling by invitation
Phase
NA
Sponsor
University of Ulster
Enrolment target
28
Start
01 Apr 2025
Estimated completion
31 Mar 2026

What is this study about?

When we eat plant-based foods like vegetables, fruits, nuts, and beans, they come with natural cell walls. Think of these like tiny protective casings around each plant cell. While these cell walls are great for the plant, they can sometimes make it a bit trickier for our digestive system to fully break down the food and get all the nutrients and energy inside.

This study wants to learn more about how important these plant cell walls are for our digestion. It will compare two different chickpea meals that have roughly the same amount of protein, fat, and carbohydrates, and the same total energy. The key difference is how 'intact' the chickpeas are. One meal will use whole chickpeas, where the cell walls are mostly unbroken. The other meal will use chickpeas that have been broken down, like in a burger, so the cell walls are less intact.

By comparing these two meals, the researchers hope to understand if breaking down these plant cell walls helps our bodies absorb more of the macronutrients (like protein, fat, and carbohydrates) and other helpful compounds found in chickpeas. They will be particularly interested in how much energy is absorbed and how this affects levels of sugars, important amino acids, and fats in the blood. This information could help us understand better ways to prepare plant-based foods to get the most nutritional benefit.

Key takeaways

  • This study looks at how food preparation affects nutrition.
  • It focuses on how well bodies absorb nutrients from chickpeas.
  • Compares whole chickpeas to mashed chickpeas.
  • Aims to understand the role of plant cell walls in digestion.
  • Specific to people who have had an ileostomy.

Who may be eligible?

To take part in this study, you need to be an adult between 18 and 60 years old. An important requirement is that you must have had an ileostomy operation, and it needs to have been at least 1 and a half years ago. You should also be a non-smoker.

For safety, we cannot include pregnant or breastfeeding women in this study. Also, if you know you are allergic to nuts or celery, or if you are currently a smoker, you won't be able to participate. This helps ensure everyone in the study is as similar as possible, making the results clearer and safer for everyone involved.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

  1. Are you between 18 and 60 years old?
  2. Have you had an ileostomy operation at least 1.5 years ago?
  3. Are you a non-smoker?
  4. Are you NOT pregnant or breastfeeding?
  5. Are you NOT allergic to nuts or celery?
Answer every question to see your result.

What does participation involve?

The information provided does not detail the specifics of what taking part involves such as the number of visits, assessments, medication, or total duration. However, generally, studies like this involve having specific meals provided by the research team and collecting samples (like blood or ileostomy output) after eating. This helps measure how your body processes the different chickpea meals. The study compares two types of chickpea meals, so you would likely consume each type at different times, with careful monitoring.

Potential risks and benefits

Taking part in research always has a balance of potential benefits and risks. A potential benefit of this study is helping researchers understand more about how our bodies absorb nutrients from plant-based foods, which could improve dietary advice in the future. The risks are likely minimal, possibly involving mild discomfort from blood sampling or following a specific diet. You will always have the right to withdraw from the study at any time without giving a reason, and this will not affect your usual medical care.

Locations (1)

Some site locations are approximate. We're improving this — please verify with the trial team before travelling.
  • Human Intervention Studies Unit, Ulster University
    Verified postcode
    Coleraine, United Kingdom

Common questions

What is an ileostomy?

An ileostomy is a surgical procedure where the end of your small intestine (ileum) is brought out through an opening in your tummy (abdomen). This allows waste to leave your body into a small bag.

Why are you studying chickpeas?

Chickpeas are a common plant-based food. We want to understand how preparing them differently (whole versus mashed) affects how much goodness your body gets from them, especially the nutrients and energy.

What's the difference between 'intact' and 'broken' chickpeas?

Intact chickpeas are whole, like you'd find in a salad. Broken chickpeas are mashed or blended, like in a burger, so their natural cell walls are not as complete.

Will I have to eat special meals?

Yes, you will be given specific chickpea meals to eat as part of the study, designed to test the difference between intact and broken chickpeas.

What will happen to the information collected from me?

The information collected will be used by the researchers to understand more about nutrition and absorption. Your privacy will be protected, and your personal details will not be shared.

How to find out more

Always speak to your GP or specialist before deciding to take part in a study.

Interested in taking part?

Register your interest

Share your details and the research team for "Bioavailability From Chickpea Meals in Ileostomists?…" will contact you if you may be eligible. Always speak to your GP before agreeing to take part.

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