Not yet recruitingInterventional

The use of ChloroStay mouthwash for better dental care during brace treatment

Children wearing fixed braces often find it tricky to clean their teeth properly, which can sometimes lead to dental problems. This study is exploring if a specific mouthwash, called ChloroStay™, could make a difference. We're inviting children aged 12-16 who are currently undergoing routine brace treatment to take part. Half of them will add the ChloroStay™ mouthwash to their daily routine, while the other half will stick to their usual brushing habits. We will then follow everyone's dental health throughout their brace treatment to see if the mouthwash helps keep teeth and gums healthier. This could offer a simple way to improve dental care for many young people with braces.

At a glance

Status

Not yet recruiting

Sponsor

Queen Mary University of London

Enrolment target

Start

01 Sep 2026

Estimated completion

01 Mar 2027

Optimal dental and gum care during routine orthodontic treatment

What is this study about?

When children wear fixed braces, keeping their teeth and gums clean can be a real challenge. Bits of food can get stuck around the brackets and wires, making it harder to brush effectively. Over time, this can sometimes lead to issues like gum inflammation or white spots on the teeth (early signs of decay).

This study wants to find out if using a special mouthwash called ChloroStay™ can help children avoid these problems. The researchers think that this mouthwash might offer extra protection and make it easier to maintain good dental health while braces are on. By comparing children who use the mouthwash with those who don't, they hope to understand if ChloroStay™ really makes a positive difference.

The findings from this study could be very important. If the mouthwash proves to be effective, it could become a simple and widely recommended addition to dental care routines for children and teenagers undergoing brace treatment. This could help many young people finish their orthodontic journey with healthier teeth and gums.

Key takeaways

This study investigates if a special mouthwash helps keep teeth and gums healthy during brace treatment.
It's for children aged 12-16 currently undergoing fixed brace treatment.
You'll either use the mouthwash or stick to your usual brushing routine.
The study aims to improve dental care for young people with braces.
Funding comes from the company that developed the mouthwash.
There are no known serious risks, but minor side effects like irritation are possible.

Who may be eligible?

This study is looking for young people between 12 and 16 years old. You need to be currently having fixed braces put on your top and bottom teeth as part of your regular hospital treatment, and your braces should be expected to be on for at least one year.

Before you start the study, your teeth and gums should already be in good health, with no existing problems like white spots or serious decay. Your parents or guardians must also be able to understand the study information and agree for you to take part.

There are some reasons you wouldn't be able to join. For example, if you've already had fixed braces before, if you have certain existing dental conditions, or if you're taking part in another medical study. You also need to be able to understand English, both spoken and written.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Is your child between 12 and 16 years old?
Is your child currently planned to have fixed braces on both their top and bottom teeth?
Are your child's teeth and gums generally healthy before starting brace treatment?
Can you, as a parent or guardian, provide informed consent for your child to join?
Does your child understand and speak English well enough for the study information?

Answer every question to see your result.

What does participation involve?

If you decide to take part in this study, you’ll continue to brush your teeth and gums like you normally would. You’ll be put into one of two groups by chance, like flipping a coin. One group will be asked to add the ChloroStay™ mouthwash to their daily routine, using it as instructed. The other group will stick to their usual brushing habits without the mouthwash. Both groups will have regular check-ups during your brace treatment, where the study team will look at your teeth and gums to see how they are doing. The study is expected to run from October 2025 until October 2028, and your involvement will last for the duration of your brace treatment.

Potential risks and benefits

There are some potential benefits to joining this study. If you're in the group using the mouthwash, it might help keep your teeth and gums healthier during your brace treatment. As for risks, there are no serious side effects expected from ChloroStay™ mouthwash. However, like with any dental product, some children might find it irritates their mouth a little or they might not like the taste. You are free to withdraw from the study at any time, for any reason, without it affecting your medical care.

Locations (1)

Some site locations are approximate. We're improving this — please verify with the trial team before travelling.

Barts Health NHS Trust
City only
London, England

Common questions

What is ChloroStay™ mouthwash?

ChloroStay™ is a special mouthwash that researchers think might help keep teeth and gums healthy for children wearing braces.

Who is funding this study?

The study is being funded by Schottlander and Davis Ltd, the company that created the ChloroStay™ mouthwash.

How long will the study last if I join?

Your involvement in the study will last for the duration of your brace treatment, checking in with your progress regularly.

Will I still use my regular toothpaste and brush?

Yes, all children in the study will continue to use their usual toothbrush and toothpaste as normal.

Can I leave the study at any time?

Yes, you or your child can leave the study at any point, and it won't affect your orthodontic treatment or care.

How to find out more

Ama Johal

a.s.johal@qmul.ac.uk +44 2078828631 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.