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Global Overweight and oBesE (GLOBE) Patient Registry, Development and Implementation of Disease-specific: Severity, Quality of Life and Cost Instruments.

This study, called GLOBE, is creating new ways to understand how being overweight (BMI over 25) or obese affects people in the UK. We're developing tools to measure how serious someone's condition is, how it impacts their quality of life, and the financial costs involved. Current tools often don't include people who are overweight or very obese, or fully consider how it affects daily life and finances. By gathering information from both patients and healthcare professionals, we hope to get a full picture. This will help us to better understand the challenges, develop more inclusive ways to measure the condition's severity, and guide earlier support strategies to help people live healthier lives.

At a glance

Status
Recruiting
Sponsor
Medialis Ltd.
Enrolment target
500
Start
01 Nov 2025
Estimated completion
01 Aug 2026

What is this study about?

This study, called GLOBE, is all about getting a much clearer picture of what it's like to live with being overweight or obese in the UK. You might have heard of BMI (Body Mass Index), which is a way to measure if your weight is healthy for your height. This study is for people with a BMI over 25, which includes those who are considered overweight or obese.

Currently, many of the tools doctors use to understand and measure the impact of overweight and obesity don't always capture the full story. For example, they might mainly focus on people who are very obese or those already having specific medical or surgical treatments. This means that many people, including those who are overweight or extremely obese, might not have their experiences fully understood. Also, current tools don't always look at how someone's weight affects their daily life, their overall well-being, or the financial costs involved.

This study aims to change that. We want to develop better, more complete tools that truly reflect the experiences of a wide range of people with a BMI over 25. We'll be looking carefully at symptoms, other health conditions that might be present, how well people feel they are living their lives (quality of life), and the various costs involved. By listening to both patients and healthcare professionals, we hope to create new ways to measure the severity of being overweight or obese that are much more inclusive. This valuable information will then help doctors and healthcare services plan better and earlier support strategies, ultimately helping more people to live healthier and happier lives.

Key takeaways

  • This study aims to improve understanding of how being overweight or obese affects people.
  • It will help create new tools to measure the severity, quality of life impact, and costs involved.
  • Your input could lead to better support and earlier interventions for people in the future.
  • Participation involves completing surveys; no medication or treatments are given.
  • Anyone aged 18 or over with a BMI higher than 25 can potentially take part.
  • You can withdraw from the study at any time.

Who may be eligible?

To take part in this study, you need to be an adult aged 18 or over. This study is open to anyone who believes their BMI is over 25. You should be able to read, write, and comfortably chat in English, and be happy to take part in all the study activities.

We're also looking for healthcare professionals who are 18 or over, qualified, involved in caring for patients with a BMI over 25, and can read, write, and converse in English. They also need to be willing to take part in all study activities.

However, you won't be able to take part if you have health conditions that might make it difficult to participate fully in the study, or if you're not able to fully understand what participating in a study means.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

  1. Are you 18 years old or older?
  2. Do you believe your BMI is over 25?
  3. Can you read, write, and have conversations in English?
  4. Are you happy to complete surveys as part of the study?
  5. Do you feel you can generally follow study instructions?
Answer every question to see your result.

What does participation involve?

This study involves completing surveys. You won't be given any medication, and there are no direct appointments or follow-up visits involved. The total duration of your participation will depend on how long it takes you to complete the surveys. There is no specified timeframe given for how long the surveys will take, as the main goal is to gather information to develop new measurement tools.

Potential risks and benefits

A potential benefit of joining this study is that your input will directly help create better tools for understanding and supporting people who are overweight or obese in the future. This could lead to improved healthcare and support for many. As this study mainly involves completing surveys, there are no notable physical risks. However, you might find some questions about your health, quality of life, or finances sensitive or emotionally challenging. You are free to stop participating at any time without giving a reason.

Locations (1)

Some site locations are approximate. We're improving this — please verify with the trial team before travelling.
  • Online recruitment
    Verified postcode
    Milton Keynes, United Kingdom· Recruiting

Common questions

What is BMI?

BMI stands for Body Mass Index. It's a measure that uses your height and weight to work out if your weight is healthy. A BMI over 25 is generally considered overweight, and over 30 is considered obese.

What does 'quality of life' mean in this study?

In this study, 'quality of life' refers to how your health and condition affect your daily activities, your feelings, your relationships, and your overall well-being.

Will I be given any medication or treatments?

No, this study is not testing any medication or new treatments. It's about gathering information to better understand the impact of being overweight or obese and to develop new measurement tools.

How long will I need to be involved in the study?

Your involvement in the study will be limited to the time it takes you to complete the surveys. There will be no ongoing appointments or follow-ups once you've completed them.

Is my information kept private?

Yes, research studies must follow strict rules to protect your personal information and ensure your privacy.

How to find out more

Omolade Allen, PhD

Always speak to your GP or specialist before deciding to take part in a study.

Interested in taking part?

Register your interest

Share your details and the research team for "Global Overweight and oBesE (GLOBE) Patient Registry, Develo…" will contact you if you may be eligible. Always speak to your GP before agreeing to take part.

Discussion

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