A Prospective Clinical Study to Evaluate the Safety and Effectiveness of Pulmonary Vein Isolation Plus Box Isolation of Fibrotic Areas With the Globe® Pulsed Field System for Treating Patients With Symptomatic Paroxysmal or Persistent Atrial Fibrillation

To join this study, you would need to have been diagnosed with atrial fibrillation that causes symptoms, whether it comes and goes (paroxysmal) or is constant (persistent). You should also have tried at least one antiarrhythmic medication (a type of heart rhythm drug) that either didn't work for you or caused side effects that you couldn't tolerate.

There are also some reasons why you might not be able to join. For example, if your atrial fibrillation has been constant for more than a year, or if it's caused by something else that can be fixed, like a thyroid problem. You also wouldn't be able to participate if you've had a blood clot or stroke recently, or if you've had major heart procedures in the last few months. If you have another heart device implanted, such as a pacemaker, or if your heart muscle is significantly weakened, you also couldn't join. There are also limits on body weight and the size of your heart's upper chamber.

If you decide to take part in this study, you would undergo the treatment using the Globe Pulsed Field System. Your safety and how well the treatment is working would be monitored closely for 12 months. This would involve a series of follow-up appointments and checks at the clinic. These appointments would likely include physical exams, heart rhythm recordings (like ECGs), and possibly blood tests to make sure you're doing well. You would also be asked about any symptoms you're experiencing. The total duration of your active participation in the study, including the procedure and all follow-up, would be at least one year.