Ongoing, recruitingHuman Pharmacology (Phase I)- OtherInterventional

Open label study to investigate patch adhesion of an Esflurbiprofen-containing patch in healthy volunteers

This research is a special type of study to understand how well a new stick-on patch stays put on people's skin. The patch contains a medication called Esflurbiprofen, which can help with pain. However, this study isn't about whether the medicine works for pain or not. Instead, it's focused purely on the 'stickiness' of the patch itself when worn by healthy volunteers. This is an important step in developing new medicines, as patches need to stay on securely to deliver medicine effectively. It's an early-stage study, meaning it's one of the first steps in testing a new treatment in people.

At a glance

Status

Ongoing, recruiting

Phase

Human Pharmacology (Phase I)- Other

Sponsor

Teikoku Seiyaku Co. Ltd.

Enrolment target

Start

13 Nov 2025

Patch adhesion trial with healthy subjects therapeutical indication not studied

What is this study about?

Imagine a sticky patch that delivers medicine through your skin. For it to work properly, it needs to stay firmly attached, even with everyday movements. This research study is designed to explore just that: how well a new patch, containing a medicine called Esflurbiprofen, sticks to the skin of healthy people.

It's important to understand that this study is not looking at whether the Esflurbiprofen medicine in the patch helps with pain or any other medical condition. That's a different kind of study. This particular research is focused purely on the patch's physical properties, specifically its 'adhesion'. Researchers want to see if it peels off, if it stays on during different activities, and generally how reliable it is at staying attached.

This kind of study is a very early step in bringing new medicines to patients. Before a patch can be widely used, scientists need to be sure it will stay on effectively. Gathering this information helps ensure that future patients who might use the patch will receive their medication reliably and without issues caused by the patch falling off.

Key takeaways

This study tests how well a new medicine patch sticks to the skin.
It's for healthy adults, at least 18 years old.
The study isn't about treating pain; it's about the patch's stickiness.
Participation helps scientists understand how to make better patches.
Risks are generally low, mainly skin irritation.
You can stop participating at any time.

Who may be eligible?

To join this study, participants generally need to be healthy adults. This means you shouldn't have any major ongoing health conditions or be taking many regular medications that could interfere with the study.

The study is open to both men and women. You need to be at least 18 years old to take part. There's no upper age limit mentioned, so older adults could also be eligible, as long as they meet the other health criteria.

Because this study is about how a patch sticks, it's likely that your skin condition will be important, especially on the areas where the patch would be applied.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you 18 years old or older?
Are you generally healthy, without major ongoing medical conditions?
Are you prepared to wear a patch on your skin for a period?
Are you able to attend clinic visits as required by the study?
Do you understand that this study is not for treating any illness?

Answer every question to see your result.

What does participation involve?

The information provided is very brief, but typically, taking part in a study like this would involve a few visits to a clinic. You would have the patch applied, and then researchers would monitor how well it stays on over a set period, possibly for several days. This might include checking the patch regularly, taking photographs, or performing simple movements to see if the patch is affected.

You would not be trying to treat a medical condition with the patch; instead, you would simply be wearing it as directed. There would likely be an initial health check to confirm you are suitable, and follow-up checks after the patch is removed. The total duration of your participation, including screening and follow-up, would be determined by the study design.

Potential risks and benefits

The main benefit of taking part in a study like this is contributing to medical science and helping to develop new treatments that could benefit patients in the future. You might also receive a small payment for your time. Potential risks are generally low for a patch adhesion study in healthy volunteers but could include mild skin irritation or redness where the patch is applied. You have the right to withdraw from the study at any time, for any reason, without it affecting your medical care.

Locations (1)

Some site locations are approximate. We're improving this — please verify with the trial team before travelling.

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Unverified
Germany

Common questions

What is Esflurbiprofen?

Esflurbiprofen is a type of medicine that helps to reduce pain and inflammation. However, in this study, we are not looking at if it helps with pain, just how well the patch sticks.

Why is it important to know how well a patch sticks?

For a medicine patch to work, it needs to stay on your skin properly so the medicine can get into your body. This study helps make sure any future patches using this medicine will be reliable.

Will I get any medicine to treat pain in this study?

No, this study is not designed to treat any medical condition or pain. It's purely about how the patch sticks to healthy skin.

Do I have to be sick to join this study?

No, quite the opposite! This study is specifically looking for healthy volunteers, meaning people who don't have any major ongoing health problems.

How long will I need to be involved in the study?

The information doesn't say exactly, but early-stage studies like this usually involve a few clinic visits over a short period, potentially a few days or weeks in total.