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A UK study of minimally invasive emergency treatment of sudden bleeding from the lower bowel

This study focuses on people in the UK and other countries who have experienced sudden, serious bleeding from their lower bowel. Instead of major surgery, many of these patients had a less invasive procedure called embolisation. This involves doctors using small tubes guided by X-rays to find the bleeding spot and then blocking the affected blood vessel to stop the bleeding. The study will look at existing hospital records to understand how well this procedure works, what factors lead to a successful outcome, and if the timing of the treatment makes a difference. The goal is to learn from past cases to help improve emergency care and make future treatments even better for patients needing this kind of help.

At a glance

Status
Recruiting
Sponsor
University Hospitals Plymouth NHS Trust
Enrolment target
800
Start
01 Feb 2026
Estimated completion
01 Feb 2028

What is this study about?

Imagine suddenly having serious bleeding from your back passage – it can be very worrying and even life-threatening. Traditionally, a big operation might have been the only way to stop it, but this can have many risks. Nowadays, doctors have a clever way to stop this bleeding using a method called embolisation.

This procedure involves specialists, called interventional radiologists, making a tiny cut, often in the groin, and carefully guiding a very thin tube, like a spaghetti strand, through your blood vessels. They use X-ray pictures to see where they are going. When they find the exact spot that's bleeding, they can inject special tiny particles or coils through the tube to block that specific blood vessel. This stops the bleeding while making sure the rest of your body still gets enough blood. It's often quicker and safer than major surgery.

This study is looking back at records of patients who have already had this embolisation procedure for sudden lower bowel bleeding. The doctors want to understand how it worked for them. They'll be checking things like whether the bleeding stopped, if it came back, and if there were any problems. By looking at a lot of past cases, they hope to find out what makes the treatment most successful and how quickly it needs to be done. The results will help hospitals improve their emergency plans and might lead to even better care for people with similar bleeding in the future.

Key takeaways

  • The study looks at existing records of patients who had special treatment for sudden bowel bleeding.
  • The treatment is called embolisation, which avoids major surgery.
  • It aims to understand what makes this treatment successful and how to improve it.
  • No new tests or procedures are involved for patients.
  • The findings could help improve emergency care for similar conditions in the future.
  • The study will run until October 2028.

Who may be eligible?

This study is looking at information from adults aged 16 or over who previously had a special procedure called embolisation for sudden bleeding from their lower bowel. This bleeding must have happened between January 2023 and June 2025.

They are specifically looking at bleeding that isn't from 'varices' (which are swollen veins often linked to liver problems) and isn't from the upper part of the digestive system (like the stomach or gullet). If you had embolisation for bleeding from varices or for bleeding that lasted longer than 30 days, your information would not be included.

Quick self-check
  • Are you 16 years old or older?
  • Did you have an embolisation procedure to stop sudden bleeding from your lower bowel?
  • Did this procedure happen between January 2023 and June 2025?
  • Was your bleeding *not* related to 'varices' (swollen veins) or from your upper digestive system?
  • Was your bleeding sudden (not prolonged for over 30 days)?

This is a guide only — the research team will confirm whether you can take part.

What does participation involve?

Good news! This study doesn't ask you to do anything extra. You won't need any new tests, procedures, or even extra hospital visits. The researchers are simply looking back at existing hospital notes, X-ray reports, and other documents from patients who have already had the embolisation procedure for lower bowel bleeding. They will collect information about how you presented to the hospital, what was found on your scans, details about how your embolisation procedure went, and what happened afterwards, such as if the bleeding stopped or if there were any issues. Your medical records already hold all the information they need.

Potential risks and benefits

There are no direct benefits for you as an individual patient because this study is only looking at existing records; you won't be having any new treatments or checks. However, the information gathered will help doctors better understand how effective embolisation is for lower bowel bleeding and could improve care for future patients. Importantly, there are no additional risks to you for taking part in this study, as it only involves reviewing medical records, not performing any new procedures. You also have the right to have your data withdrawn from the study if you change your mind, though given it's retrospective, this usually means ensuring no new data is accessed.

Locations (40)

  • University Hospitals Plymouth NHS Trust
    Plymouth, England
  • Norfolk and Norwich University Hospitals NHS Foundation Trust
    Norwich, England
  • Sheffield Teaching Hospitals NHS Foundation Trust
    Sheffield, England
  • Oxford University Hospitals NHS Foundation Trust
    Oxford, England
  • Liverpool University Hospitals NHS Foundation Trust
    Liverpool, England
  • Hull University Teaching Hospitals NHS Trust
    Hull, England
  • Aberdeen Royal Infirmary
    Aberdeen, Scotland
  • West Suffolk NHS Foundation Trust
    Bury St. Edmunds, England
  • Cambridge University Hospitals NHS Foundation Trust
    Cambridge, England
  • Gloucestershire Hospitals NHS Foundation Trust
    Cheltenham, England
  • The Newcastle upon Tyne Hospitals NHS Foundation Trust
    Newcastle upon Tyne, England
  • London North West University Healthcare NHS Trust
    Harrow, England

+28 more sites — see the official record for the full list.

Common questions

What is 'embolisation'?

It's a procedure where a doctor uses tiny tubes guided by X-rays to find and block a bleeding blood vessel from the inside to stop bleeding without major surgery.

Why is this study being done?

Doctors want to learn how well embolisation works for lower bowel bleeding by looking at past cases. This helps them improve future treatments and hospital policies.

Do I need to do anything if I'm part of this study?

No, you don't need to do anything. The study only looks at existing hospital records and information that's already there.

Is my personal information kept private?

Yes, all data collected will be handled carefully to protect your privacy and will be anonymised where possible so you cannot be identified.

When will the study results be known?

The study runs until October 2028, so results would likely be available after that date.

How to find out more

Deevia Kotecha

Always speak to your GP or specialist before deciding to take part in a study.

Discussion

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