Active not recruitingOBSERVATIONAL

Examine the Epidemiology and Outcomes of Transitions From PD-to-HD in Canada

This study is investigating people in Canada who are undergoing kidney replacement therapy. Specifically, it's focusing on individuals who begin with peritoneal dialysis (PD) and later transition to hemodialysis (HD). This change from one type of dialysis to another is quite common, and researchers believe it might be linked to certain health outcomes, but we don't fully understand it at a national level. By looking at large health databases, the study aims to find out how often these switches happen, what factors might lead to them, and what the long-term effects are. This includes looking at things like how long people live, if they receive a kidney transplant, if they switch dialysis methods again, and how often they need to go to the hospital after switching.

At a glance

Status

Active not recruiting

Sponsor

Ciusss de L'Est de l'Île de Montréal

Enrolment target

17,000

Start

01 Jan 2005

Estimated completion

01 Dec 2027

Peritoneal Dialysis (PD)Hemodialysis Kidney Replacement Therapy

What is this study about?

When your kidneys aren't working properly, you might need a treatment called kidney replacement therapy. Two common types of this treatment are peritoneal dialysis (PD) and hemodialysis (HD). Sometimes people start with PD but then switch to HD. This study wants to understand this switch better. Think of it like changing routes on a journey; the researchers want to know why people change routes, how often it happens, and what the rest of their journey looks like afterwards.

Researchers will use existing health information from large databases in Canada. They aren't asking people to take new medicines or have new tests. Instead, they're looking at records to see who started PD, who then switched to HD, and what happened to them over time. This includes checking things like whether people lived longer, if they eventually received a kidney transplant, if they had to go to the hospital, or if they changed their dialysis method again.

The main goal is to get a clearer picture of this journey from PD to HD across Canada. By understanding more about this common change, doctors might be able to offer better advice and care to patients in the future. It's about learning from past experiences to improve future care for people with kidney disease.

Key takeaways

The study explores why and how often people switch from peritoneal dialysis to hemodialysis.
It uses existing, anonymous health records from Canadian adults.
The research aims to understand health outcomes after switching dialysis types.
There's no direct participation needed from individuals in this record-based study.
Findings could help improve care for future kidney patients.

Who may be eligible?

This study is looking at information from adults aged 18 or older who started dialysis in Canada between January 1, 2005, and December 31, 2018. To be included, these individuals must have used peritoneal dialysis for more than 30 days in a row.

Some people's data will not be included. This applies to those who started dialysis in Quebec or Manitoba during the study period, or if they started dialysis in another country. Also, if a person had a kidney transplant before starting dialysis, or if there's missing information about which type of dialysis they first used, their data won't be part of this study.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Were you 18 years old or older when you started dialysis?
Did you start dialysis in Canada (but not in Quebec or Manitoba)?
Did you start dialysis between January 1, 2005, and December 31, 2018?
Did you use peritoneal dialysis (PD) for more than 30 days in a row when you first started?

Answer every question to see your result.

What does participation involve?

This study is different from many others because you won't be asked to do anything directly. You won't need to visit a clinic, take new medicines, or have any extra tests. The researchers will be looking at existing, anonymous health records from past patients in Canada. This means your personal information won't be shared. It's a review of information that has already been collected, so there's no active participation required from individuals, and therefore no specific duration or follow-up for you.

Potential risks and benefits

Since this study only uses existing, anonymous health records, there are no direct physical risks to individuals. The benefit is that by understanding more about how people transition between dialysis types, doctors may be able to give better care and advice to future patients. There are no direct benefits for individuals whose data is used. Because it's an observational study using de-identified data, there's no 'participation' in the traditional sense, so the concept of withdrawing doesn't apply to individuals directly.

Locations (1)

CIUSSS de l'Est-de-l'ile de Montréal
Verified postcode
Montreal, Canada

Common questions

What is peritoneal dialysis (PD)?

PD is a type of kidney treatment where a special fluid is put into your tummy to clean your blood inside your body.

What is hemodialysis (HD)?

HD is another type of kidney treatment where your blood is cleaned by a machine outside your body.

Will my personal health information be shared?

No, your personal information will not be shared. The researchers only use anonymous data from health records.

Do I need to do anything to be part of this study?

No, you don't need to do anything. This study looks at existing health records, not new patients directly.

Why is this study important?

It helps doctors understand more about how people move between dialysis types, which can lead to better care for future patients with kidney disease.