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Not yet recruitingEARLY_PHASE1INTERVENTIONAL

AI in Endoscopic Transsphenoidal Surgery

This study is exploring how artificial intelligence (AI) can help during a specific type of brain surgery for a growth called a pituitary adenoma. This surgery is done through the nose and can be quite tricky. Researchers at a London hospital are testing AI that watches the surgery live on video. This AI can then identify body parts, surgical tools, and different stages of the operation. The main goal is to improve how new surgeons are taught and how the surgical team works together, all without getting in the way of the actual surgery. The AI shows its information on separate screens for junior doctors and nurses. This helps them follow along and prepare for the next steps. The study will first check if the AI system works properly, then move on to testing its safety and making improvements.

At a glance

Status
Not yet recruiting
Phase
EARLY_PHASE1
Sponsor
University College, London
Enrolment target
30
Start
01 Jun 2026
Estimated completion
31 Jan 2029

What is this study about?

This study is all about bringing clever computer technology, known as Artificial Intelligence (AI), into the operating room. They're using it to help with a special type of brain surgery performed to remove growths called pituitary adenomas. These growths are found near your brain and can cause various health problems. The surgery itself is quite delicate and precise; it's done through the nose, which means surgeons don't have to open up the skull.

Because this kind of surgery is complex, and training new surgeons can be a bit hit-and-miss, researchers at the National Hospital for Neurology and Neurosurgery in London want to make things better. They're testing AI systems that will "watch" the surgery happening live through a video camera. This AI can then quickly recognise important parts of the body, the surgical tools being used, and what stage of the operation the team is at. It's like having an extra pair of super-smart eyes in the room.

The main idea behind this study is to help improve how surgical teams learn and work together, without ever getting in the way of the main surgeon. The AI's insights are shown on separate screens for the junior doctors and nurses, not the lead surgeon. This means they can follow the surgery's progress, understand key steps, and even prepare for what's coming next, all without the main surgeon needing to stop and explain things. This means a smoother operation and better learning for everyone involved. The technology is designed to work even if the hospital internet isn't great, using special equipment that processes information right there in the operating room.

Key takeaways

  • AI is observing endoscopic brain surgery to help train surgeons.
  • The AI doesn't interfere with the actual operation or the surgeon.
  • It helps junior surgeons and nurses by showing live information.
  • There are no direct risks or benefits to patients involved in the study.
  • Participation is completely optional and won't affect your treatment.
  • The study focuses on a specific type of surgery done through the nose for a pituitary tumour.

Who may be eligible?

To be considered for this study, you need to be an adult, meaning 18 years old or older. You must also be scheduled to have a specific type of brain surgery called endoscopic transsphenoidal surgery. This is the surgery where doctors remove a pituitary tumour by going through your nose.

Crucially, you'll need to be able to fully understand what the study is about and agree to take part. This agreement, called consent, is very important.

You wouldn't be able to join the study if you are under 18 years old, or if your planned surgery is a different type, such as one that involves opening the skull or using an older "microscopic" method through the nose. Also, if for any reason you're unable to understand the study and give your consent, you wouldn't be eligible. You also have the right to change your mind and withdraw from the study at any time.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

  1. Are you 18 years old or older?
  2. Are you having surgery for a pituitary tumour through your nose (endoscopic transsphenoidal surgery)?
  3. Can you understand information about the study and agree to take part?
  4. Are you NOT having surgery through the top of your head or an older method through the nose?
  5. Do you feel comfortable providing your consent to participate?
Answer every question to see your result.

What does participation involve?

If you participate in this study, you won't have any extra appointments or assessments. The AI system will simply observe your planned endoscopic transsphenoidal surgery in the operating room. You won't be given any additional medication, and there will be no follow-up appointments specifically for this AI study after your surgery. The AI system will be used only during your time in the operating theatre for your scheduled surgery. Your participation will not change your surgical plan or your care in any way.

Potential risks and benefits

There are no direct medical benefits to you from participating in this study; its aim is to help future patients and improve surgeon training. However, there are also no known risks to your health or the success of your surgery, as the AI system is only observing and not directly involved in the surgical procedure. It won't interfere with your surgeon or the operation. You are always in control and have the complete right to say no to participating or to change your mind and withdraw from the study at any point, without affecting your medical care.

Locations (1)

Some site locations are approximate. We're improving this — please verify with the trial team before travelling.
  • National Hospital for Neurology and Neurosurgery
    Verified postcode
    London, United Kingdom

Common questions

What is AI and how is it used in this surgery?

AI is 'Artificial Intelligence', a clever computer program. In this study, it 'watches' a video of your surgery in real-time, identifying body parts and tools to help the surgical team learn and prepare.

Will the AI actually do part of my surgery?

No, absolutely not. The AI only observes and displays information. It does not control any instruments or make any decisions during your surgery. Your surgeon remains fully in charge.

Will my surgery be different if I take part?

No, your surgery will be exactly the same whether you join the study or not. The AI just runs in the background and shows information to other team members on separate screens.

What part of my body is a 'pituitary adenoma'?

A pituitary adenoma is a type of non-cancerous growth that forms on the pituitary gland, which is a small gland at the base of your brain, behind your nose.

Do I have to participate?

No, taking part is entirely your choice. Your decision will not affect your medical care in any way whatsoever.

How to find out more

Always speak to your GP or specialist before deciding to take part in a study.

Interested in taking part?

Register your interest

Share your details and the research team for "AI in Endoscopic Transsphenoidal Surgery…" will contact you if you may be eligible. Always speak to your GP before agreeing to take part.

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