All studies
RecruitingOBSERVATIONAL

Placental Characteristics Within Monochorionic Twin Pregnancies

This research is looking at the placentas from identical (monochorionic) twin pregnancies. Identical twins share a single placenta, and the way this placenta is structured can sometimes affect how the babies grow and develop. The study aims to collect detailed information about these placentas to see how their features might be linked to problems during pregnancy or after birth. By understanding this better, doctors hope to improve how they look after identical twin pregnancies in the UK. This could lead to better monitoring during pregnancy and healthier outcomes for mothers and babies.

At a glance

Status
Recruiting
Sponsor
Birmingham Women's NHS Foundation Trust
Enrolment target
65
Start
12 Dec 2024
Estimated completion
01 Feb 2027

What is this study about?

This study is particularly interested in identical twin pregnancies, which doctors call 'monochorionic' because the twins share one placenta. The placenta is a vital organ that connects the mother to the babies, providing them with food and oxygen. In identical twin pregnancies, the way this shared placenta develops and is structured can sometimes lead to different health outcomes for the babies.

Researchers want to build a detailed picture of what these placentas look like after birth, focusing on their physical features. They will then compare this information with any problems that happened during the pregnancy and how the babies were doing at birth. The main goal is to figure out if specific characteristics of the placenta can help predict potential issues or affect the care the babies receive.

The findings from this research could be really important for doctors and nurses who look after identical twin pregnancies in the UK. It might help them understand more about how the placenta influences these pregnancies and could even change how often they perform check-ups or what they look for during scans. Ultimately, this study aims to improve the care and outcomes for mothers carrying identical twins.

Key takeaways

  • This study focuses on identical (monochorionic) twin placentas.
  • It aims to understand how placenta features affect pregnancy and baby health.
  • No extra tests or visits for participants.
  • Information from this study could improve future twin pregnancy care.
  • Participation involves reviewing medical notes and examining the placenta after birth.
  • You can withdraw at any time without affecting your care.

Who may be eligible?

This study is looking for placentas from identical (monochorionic) twin pregnancies. This includes placentas from pregnancies that went smoothly and those that had complications.

The placenta needs to be sent to a special department for examination after the birth. If you have identical twins and your placenta is going to be checked there, it might be included in this study.

You would not be eligible if you are carrying single babies, non-identical twins (dichorionic twins), or more than two babies (like triplets). Also, if your baby was known to have a major birth defect or a genetic problem, that placenta would not be included.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

  1. Are you pregnant with identical twins?
  2. Will your placenta be sent for examination after birth?
  3. Are you *not* pregnant with single, non-identical twins, or more than two babies?
  4. Are your babies *not* known to have major birth defects or genetic problems?
Answer every question to see your result.

What does participation involve?

If you decide to take part, you would be asked to give your agreement (consent) for your data to be used during your pregnancy. After your twins are born, the placenta would then be carefully examined by specialists. This examination happens after delivery as part of the study. Your medical notes would also be reviewed to understand how your pregnancy went and how your babies are doing. There are no extra hospital visits or special tests for you or your babies beyond your usual pregnancy care. You wouldn't need to take any new medication. The total time you are involved in the study would span from giving consent during pregnancy until after your placenta has been analysed following delivery and your baby's outcomes are recorded.

Potential risks and benefits

Being part of this study does not involve any direct risks to you or your babies, as it only uses information and your placenta after birth, which would usually be collected anyway. It won't change your medical care. The potential benefit is that the information gathered could help future mothers with identical twin pregnancies by improving monitoring and care. You are free to withdraw from the study at any time without giving a reason, and this will not affect your or your baby's medical care in any way.

Locations (1)

Some site locations are approximate. We're improving this — please verify with the trial team before travelling.
  • Birmingham Women's and Children's NHS Foundation Trust
    Verified postcode
    Birmingham, United Kingdom· Recruiting

Common questions

What is a 'monochorionic' twin pregnancy?

This is when identical twins share a single placenta, which is the organ that provides them with food and oxygen from the mother.

Do I have to do anything extra if I join the study?

No, you wouldn't have any extra appointments, tests, or medication. The study mainly looks at information already collected during your care and your placenta after birth.

How will this study help patients?

We hope it will give doctors a better understanding of identical twin placentas, which could lead to improved monitoring and care for future identical twin pregnancies in the UK.

Will my doctors know if I don't want to participate?

Yes, they will know. Your decision will not affect the quality of care you or your babies receive in any way.

When does the placenta get examined?

The placenta is examined in detail by specialists after your twins have been born.

How to find out more

Jack Hamer, MBChB

Always speak to your GP or specialist before deciding to take part in a study.

Interested in taking part?

Register your interest

Share your details and the research team for "Placental Characteristics Within Monochorionic Twin Pregnanc…" will contact you if you may be eligible. Always speak to your GP before agreeing to take part.

Discussion

Community discussion

Powered by our forum at community.patient.info. Please be respectful — this is not medical advice.