A Study of JNJ-77242113 for the Treatment of Participants With Plaque Psoriasis Involving Special Areas (Scalp, Genital, and/or Palms of the Hands and the Soles of the Feet)

To join this study, you need to have been diagnosed with plaque psoriasis for at least six months. You should also be someone whose doctor thinks you need stronger treatments for your psoriasis, like light therapy or medicines that affect your whole body. Your psoriasis should cover at least 1% of your body, and your doctor should rate it as at least 'mild' in severity. Critically, you must have noticeable psoriasis on at least one of these 'special areas': your scalp, genital area, or the palms of your hands and soles of your feet.

Also, you need to have tried at least one skin cream or ointment (like steroid creams or Vitamin D creams) for your psoriasis that hasn't worked well enough for you. The study is open to anyone aged 12 years and over. You cannot have other types of psoriasis like erythrodermic (very red over most of the body) or pustular (with pus-filled bumps). They also can't accept you if you have another skin problem that looks like psoriasis in the same area, or if your psoriasis was clearly caused by a specific medicine you're taking.

Finally, if you have any serious, uncontrolled health problems with your kidneys, liver, heart, lungs, stomach, hormones, nervous system, blood, joints, or mental health, you might not be able to take part. It's also important that you don't have known allergies to the study medicine or its ingredients.

Unfortunately, the detailed information about what taking part involves – such as the number of visits, specific assessments, total duration, or follow-up schedule – is not provided in the brief summary. However, in a Phase 3 study like this, you would typically expect regular visits to the study clinic where you might have physical examinations, blood tests, and assessments of your psoriasis. You would be given the study medicine (either JNJ-77242113 or the placebo) to take, likely for several months. There would also be follow-up visits after you stop taking the medicine to check on your health. The total duration of participation in a study like this can vary but often lasts for many months, sometimes even over a year.