RecruitingOBSERVATIONAL

Artificial Intelligence Development for Colorectal Polyp Diagnosis

This study aims to create a new artificial intelligence (AI) program that helps doctors identify and classify polyps (growths) found during a colonoscopy. By accurately determining the risk level for each polyp, doctors can make better decisions about treatment, potentially avoiding unnecessary major surgery for benign growths. The current methods often require specialist skills, and existing AI tools are too basic. A more advanced AI could provide clearer, earlier information about a patient's bowel cancer risk, helping to personalise care. The study is being conducted internationally to gather a wide range of data and ensure the AI is reliable and fair for everyone.

At a glance

Status

Recruiting

Sponsor

King's College Hospital NHS Trust

Enrolment target

4,000

Start

04 May 2024

Estimated completion

30 May 2026

Polyp of Colon Colorectal Polyp

What is this study about?

Imagine you're having an examination called a colonoscopy, where a doctor looks inside your large bowel. During this, they might find small growths called polyps. It's really important to know if these polyps are harmless or if they could turn into cancer. Deciding this correctly helps doctors choose the best treatment for you and understand how often you'll need checks in the future.

Currently, identifying these polyps and understanding their risk often relies on special skills and equipment, which can take a long time to learn and use. Because of this, not enough people benefit from these advanced techniques. Sometimes, people even have major surgery for polyps that turn out to be harmless, meaning the surgery could have been avoided. This study is trying to change that by using a new type of computer program called Artificial Intelligence (AI).

This new AI tool is designed to help doctors quickly and accurately identify five different types of polyps during a colonoscopy. This information will help doctors decide if a polyp needs to be removed and what kind of removal is best – for example, if it can be taken out during the colonoscopy itself, avoiding major surgery. The hope is that this AI will provide clear information about polyps, no matter how much experience the doctor has, leading to more personalised and effective care for each patient. It's a big, international study to make sure the AI works well for everyone.

Key takeaways

Developing an AI tool for better polyp diagnosis during colonoscopy.
Aims to predict bowel cancer risk from polyps more accurately.
Could help avoid unnecessary major surgery for harmless polyps.
AI will help doctors choose the best treatment for each polyp.
Study involves only collecting data from your planned colonoscopy.
No new procedures or medicines for participants.

Who may be eligible?

To be part of this study, you need to be at least 18 years old. This includes people who are having a colonoscopy because they have symptoms, or as part of a screening check.

However, you can't join if you're unable to understand the study and agree to take part. Also, if you have a specific condition called 'Colitis Associated Dysplasia' or if your polyps are found at a surgical join in your bowel, you won't be able to participate. Pregnant individuals are also not able to take part.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you 18 years old or older?
Are you having a colonoscopy for symptoms or screening?
Can you understand the study information and agree to take part?
Are you not pregnant?
Do you not have Colitis Associated Dysplasia?
Are your polyps not at a surgical join in your bowel?

Answer every question to see your result.

What does participation involve?

The study does not involve any extra visits or changes to your standard colonoscopy. Participants will undergo a regular colonoscopy examination as planned by their doctor. The information about the polyps found during this colonoscopy will be used to help develop and test the new AI tool. There are no additional medications, follow-up appointments, or assessments specifically for this study. The total duration of your involvement will just be the time it takes for your colonoscopy procedure.

Potential risks and benefits

There are no direct medical risks from participating in this study, as it only involves using information from your planned colonoscopy. You won't be given any new treatments or procedures. A potential benefit is that the information gathered will help develop a new AI tool that could improve how doctors identify and treat polyps in the future, potentially leading to better outcomes for many people. You have the right to withdraw from the study at any time without it affecting your medical care.

Locations (1)

Some site locations are approximate. We're improving this — please verify with the trial team before travelling.

King's College Hospital NHS Foundation Trust
Verified postcode
London, United Kingdom· Recruiting

Common questions

What is a polyp?

A polyp is a small growth inside your bowel. Some are harmless, while others can become cancerous over time.

What is a colonoscopy?

It's a medical procedure where a thin, flexible tube with a camera is used to look inside your large bowel.

How does AI help with polyps?

AI helps by looking at images from your colonoscopy to quickly and accurately identify different types of polyps and their potential risk.

Will this study change my treatment?

No, your treatment will be decided by your doctor based on standard medical practice. This study only uses information from your colonoscopy to develop a new tool.

Is my personal information kept private?

Yes, all your health information is handled with strict privacy and confidence, as with any medical study.

How to find out more

Shraddha B Gulati, MBBS PHD MRCP

shraddha.gulati@nhs.net +442032996044 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.