RecruitingOBSERVATIONAL

Retrospective and Prospective Cohort of Patients Entering the Multidisciplinary Management of Post-Covid Syndromes

This study is about understanding Long COVID, where people continue to have symptoms long after getting over the initial SARS-CoV2 infection. Many millions of people worldwide have been affected by COVID-19, and a significant number experience lasting health problems. These ongoing symptoms can seriously impact daily life and work. While some symptoms improve with general care, others are more severe and need specialist support. Researchers are collecting information from patients who are receiving care for severe or complex Long COVID. They are also taking blood samples to look for specific markers that could help predict how the condition might develop and guide new treatment ideas.

At a glance

Status

Recruiting

Sponsor

Hospices Civils de Lyon

Enrolment target

750

Start

27 Apr 2023

Estimated completion

01 Apr 2029

Post-Covid Syndrome

What is this study about?

Since 2020, COVID-19 has been a major health concern around the world, affecting hundreds of millions of people. While most people recover fully, a significant number, sometimes called 'Long Haulers', continue to experience symptoms long after the initial infection has cleared. These lingering problems can happen regardless of how seriously ill someone was with COVID-19 in the first place.

These ongoing symptoms can make everyday life difficult and can even prevent people from returning to work. Although many people get better with regular care, some have very stubborn or severe symptoms that need expert, team-based care involving different medical professionals.

This study aims to create a detailed database of patients who have severe or complex Long COVID. By studying their medical information and blood samples, researchers hope to discover markers in the blood that could help predict how the illness will progress. This understanding could then lead to new and better ways to treat Long COVID in the future.

Key takeaways

This study helps understand Long COVID.
It uses existing medical records and blood tests.
No new treatments or extra appointments are involved.
Your contribution could lead to better future treatments.
You can withdraw from the study at any time.

Who may be eligible?

This study is looking for adults aged 18 or over who have been diagnosed with Long COVID. You might be eligible if you've been referred to a special Long COVID clinic (like the Epsilon pathway in this study) by your local doctor because your symptoms are serious and have lasted for more than four weeks, or if they are complex and have lasted for more than three months, and you had confirmed COVID-19 at the time.

You could also be eligible if you were in hospital for COVID-19 and needed oxygen for at least two days, had confirmed COVID-19 pneumonia, are not already seeing a lung specialist, are not living in a care home, and are expected to live for more than six months.

However, you cannot join the study if you do not want your health information to be used for research, or if you have other ongoing health problems that are not being treated.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you 18 years old or older?
Have you been diagnosed with Long COVID (Post-Covid Syndrome)?
Did you have confirmed COVID-19 pneumonia?
Were your symptoms severe or long-lasting (over 4 weeks, or complex over 3 months)?
If hospitalised, did you need oxygen for at least 48 hours?
Are you able to agree to your data being used for research?

Answer every question to see your result.

What does participation involve?

If you take part in this study, the researchers will collect information from your existing medical records. This includes details of your symptoms and any treatments you've received. They will also take blood samples as part of your regular care, which will then be analysed to look for specific markers related to Long COVID. You won't have any extra appointments or take any new medications just for this study; it mostly involves using information gathered during your standard medical care. The total duration of your participation would depend on how long you continue to receive care for Long COVID at the clinic.

Potential risks and benefits

There are no significant new risks involved in this study as it mainly uses information and blood samples already collected as part of your standard medical care. The main benefit is that by taking part, you are contributing to a better understanding of Long COVID, which could help develop more effective treatments for yourself and others in the future. You have the right to withdraw your consent for your data to be used in the study at any time, without it affecting your medical care.

Locations (1)

Department of Acute Pneumology and Thoracic Oncology, Hôpital Lyon Sud, Hospices Civils de Lyon
Verified postcode
Pierre-Bénite, France· Recruiting

Common questions

What is 'Post-Covid Syndrome'?

It's another name for Long COVID, which means having symptoms that continue for weeks or months after you've had COVID-19.

Will I have to take new medicine?

No, this study does not involve taking any new medications. It focuses on collecting information and blood samples during your regular check-ups.

Do I need to visit the hospital more often?

No, your study participation will not require extra hospital visits. Information will be collected during your standard care appointments.

Who is running this study?

This study is being run by researchers looking into the multidisciplinary management of Long COVID patients.

Can I leave the study at any time?

Yes, you are free to withdraw your consent for your information to be used in the study at any point, and your medical care will not be affected.

How to find out more

Sébastien COURAUD, Pr

sebastien.couraud@chu-lyon.fr +33 (0)4 78 86 44 01 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.