The Analgesic Efficacy of Pericapsular Nerve Group (PENG) Block in Patients Undergoing Primary Total Hip Arthoplasty:
This study is investigating a new way to manage pain during and after total hip replacement surgery. It's called a Pericapsular Nerve Group (PENG) block. Researchers want to find out if this block, which involves injecting a local anaesthetic drug called Ropivacaine near specific nerves, is more effective at reducing pain than a simple saltwater injection (a 'dummy' treatment). By comparing these two, they can understand if the PENG block truly helps manage pain for patients undergoing hip surgery. The study is designed so that neither the patients nor their doctors will know who receives the active drug and who receives the dummy treatment, to ensure fair results.
At a glance
What is this study about?
Imagine you're having hip replacement surgery to fix a painful hip. Doctors are always looking for better ways to make sure you have as little pain as possible, both during and after the operation. This study is testing a promising new approach to pain relief called the Pericapsular Nerve Group (PENG) block.
Think of the PENG block as a targeted way to numb the nerves that send pain signals from your hip. During this study, some patients will receive an injection of a local anaesthetic drug called Ropivacaine near these nerves. This is similar to how a dentist numbs your mouth before a procedure. Other patients will receive an injection of plain salt water, which acts as a 'dummy' treatment to help compare the true effects of the Ropivacaine.
The main goal is to see if patients who receive the PENG block with Ropivacaine experience less pain after their hip replacement compared to those who get the salt water. This research is important because finding better ways to control pain can help people recover more comfortably and quickly after surgery. The study is set up in a very careful way to ensure the results are accurate and trustworthy.
Key takeaways
- This study evaluates a new pain relief technique (PENG block) for hip replacement surgery.
- It aims to see if the PENG block reduces pain more effectively than a dummy treatment.
- Participants will receive either a local anaesthetic or salt water.
- The study is 'double-blind,' meaning no one knows who gets which treatment.
- Findings could improve pain management after hip surgery.
Who may be eligible?
To join this study, you would need to be an adult (over 18) who is planning to have a hip replacement operation for the first time because of common wear and tear (primary coxarthrosis). Your surgery would need to be a specific type, using a 'minimally invasive anterolateral approach' and a standard implant system. You must also be able to understand the study and agree to take part.
There are several reasons why you might not be able to join. For example, if you already take strong painkillers regularly (like opioids) or have ongoing chronic pain, the study results might be harder to interpret fairly. Also, if you have certain medical conditions, infections near the injection site, or cannot take the medications used in the study (Ropivacaine, Metamizole, or Diclofenac), you wouldn't be eligible. Individuals who have had previous hip or pelvis operations, or have certain complex hip conditions or spine problems, are also not able to participate.
Could this study suit you?
Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.
- Are you over 18 years old?
- Are you having your first hip replacement for common wear-and-tear?
- Do you not regularly use strong opioid painkillers?
- Do you not have any ongoing severe chronic pain?
- Can you safely take medicines like ropivacaine, metamizole, or diclofenac?
- Have you not had previous hip or pelvis surgery?
What does participation involve?
If you decide to take part, you'll first have a discussion with the study team and, if you agree, sign a consent form. While you are having your hip replacement surgery, you will receive an injection. This will either be the active pain-numbing medicine (Ropivacaine) or a dummy salt water injection. Neither you nor your doctors will know which one you receive. You will have regular checks on your pain levels and how you're feeling after the surgery. The study team will monitor your progress closely during your hospital stay and for a period afterwards.
Potential risks and benefits
Locations (1)
- Diakonie-Klinikum StuttgartVerified postcodeStuttgart, Germany· Recruiting
Common questions
What is a PENG block?
It's an injection near specific nerves around your hip to help numb the area and reduce pain during and after hip replacement surgery.
Will I know if I'm getting the real medicine or the dummy treatment?
No, neither you nor your doctors will know, which helps make the study results fair and accurate.
Why is this study important?
It helps doctors find better ways to manage pain for patients undergoing hip replacement surgery, which could lead to a more comfortable recovery.
Are there any side effects?
As with any injection, there's a small risk of things like bruising or infection. The study team will discuss potential medication side effects with you.
Can I leave the study if I change my mind?
Yes, you can choose to stop participating at any point, and your decision will not affect your medical care.
How to find out more
Rainer Meierhenrich, Prof. Dr.
Always speak to your GP or specialist before deciding to take part in a study.
Interested in taking part?
Discussion
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