RecruitingNAINTERVENTIONAL

Animal and Microbial-based Dietary Protein Efficiency in Adults

This study aims to understand how various protein sources, including those from animals and microbes like yeast, help adults build and maintain their body's protein. Researchers are interested in finding sustainable, non-animal protein options because of their lower environmental impact compared to animal proteins. They will compare yeast, whey (dairy), and collagen proteins. To see how well these proteins are used by the body, participants will undergo a special 'breath test' developed by the researchers, as well as providing urine samples. The results of this study will help us learn more about which types of protein are most effective for keeping adults healthy and maintaining muscle mass.

At a glance

Status

Recruiting

Phase

Sponsor

Daniel Moore

Enrolment target

Start

01 Jul 2025

Estimated completion

31 Dec 2025

Protein Metabolism

What is this study about?

You might wonder about the best types of protein to eat for your health, especially with concerns about the environment. This study is all about understanding how different protein sources, including newer options from microbes like yeast, help your body build and repair itself.

Proteins are essential building blocks for our bodies, helping with everything from muscle to skin and hormones. While we know animal proteins like meat and dairy are good sources, researchers are increasingly exploring non-animal options that are better for our planet. This study wants to see if these newer, more sustainable proteins work just as well as traditional animal proteins.

By comparing a yeast protein supplement with well-known animal proteins like whey (from milk) and collagen, the study aims to figure out which types of protein are most efficient. This knowledge could help us make better dietary choices for maintaining our health and muscle as we age, while also considering the environment.

Key takeaways

This study compares animal and non-animal protein sources.
It uses breath and urine tests to track protein use in the body.
The goal is to understand how different proteins support health and muscle.
Participants must be healthy, active adults aged 18-45.
The findings could help identify effective, sustainable protein options.
You can withdraw from the study at any time.

Who may be eligible?

This study is looking for healthy men and women between 18 and 45 years old who are physically active. You'll need to confirm you're healthy using special questionnaires and be willing to follow all study rules.

For women, you'll need to have a regular menstrual cycle or be taking certain types of birth control pills (specifically, combined oral contraceptives with 21 active pills, like Yaz or Marvelon). If you use other forms of hormonal contraception, like a hormonal coil, or combined pills with more than 21 active pills or different hormone patterns, you won't be able to join.

You cannot take part if you smoke, use illegal drugs, or have recently been on a vegan diet (within the last 6 months). Also, if you have allergies to dairy or yeast, or have taken part in similar studies using special 'stable isotopes' in the past year, you won't be eligible.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you between 18 and 45 years old?
Are you generally healthy and physically active?
Do you not smoke or use illegal drugs?
Have you not been on a vegan diet for the last 6 months?
Are you willing to agree to all study rules?
If female, do you have a regular period or use a specific type of combined birth control pill (21 active pills)?

Answer every question to see your result.

What does participation involve?

If you decide to take part, you'll be given different protein supplements to try. The study will mainly use a special 'breath test' and collect urine samples to see how your body uses these proteins. The exact number of visits isn't specified, but you'll need to adhere to the study rules and any dietary instructions given. There's no mention of taking medication, only supplements. The total duration of your participation isn't provided, but you'll be informed of all time commitments before you agree to join.

Potential risks and benefits

Taking part in this study could help us learn valuable information about protein nutrition, which might benefit many people in the future, including yourself, by identifying the most effective and sustainable protein sources. While specific risks aren't listed, there's always a small chance of unexpected side effects from supplements. You might also find the breath tests and urine collections a bit inconvenient. You are free to withdraw from the study at any time, for any reason, without it affecting your medical care.

Locations (1)

Kinesiology & Physical Education
Verified postcode
Toronto, Canada· Recruiting

Common questions

What is the study trying to find out?

It wants to see how well different protein sources, like yeast and animal proteins, help your body build and repair itself.

What kind of tests will I have?

You'll have 'breath tests' and provide urine samples to measure how your body uses protein.

Will I have to take any medication?

No, you will only be given different protein supplements to try, not medications.

What if I take birth control pills?

Some specific types of birth control pills (combined, 21 active pills) are allowed, but others are not. Please check with the study team.

Can I stop participating if I change my mind?

Yes, you can leave the study at any time without any problems or needing to give a reason.

How to find out more

Daniel R. Moore, Ph.D.

drmoore@utoronto.ca 416-946-4088 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.