Impact of an Early Identification Program for First-Episode Psychosis on the Duration of Untreated Psychosis
This study is investigating a new program, PRESTO, designed to help people who are experiencing their first episode of psychosis. Psychosis is a serious condition that can affect your thoughts and feelings, and in many cases, it can develop into schizophrenia. Getting help quickly is really important for better long-term health. The study wants to see if the PRESTO program, which helps people get specialist care sooner, can shorten the 'Duration of Untreated Psychosis' (DUP). DUP is simply the time between when someone first shows clear symptoms of psychosis and when they start getting proper psychiatric care. The program aims to do this by educating the public, training frontline professionals like GPs and teachers, and improving how these professionals work with specialist mental health services.
At a glance
What is this study about?
Imagine you or someone you know starts experiencing symptoms like seeing or hearing things that others don't, or having unusual thoughts. This is sometimes called a 'first episode of psychosis'. It can be very upsetting and confusing, and it's a serious medical condition. For many people, if not treated quickly, it can lead to conditions like schizophrenia.
Doctors and researchers have found that getting help as soon as possible after these symptoms appear can make a big difference to how well someone recovers and their long-term health. The time between when someone first has clear symptoms and when they actually start getting proper treatment is called the 'Duration of Untreated Psychosis' (DUP). The shorter this time, the better the chances for a good recovery.
This study is looking at a new program called PRESTO, which aims to make it easier and quicker for people experiencing their first episode of psychosis to get the specialist care they need. The PRESTO program tries to achieve this in three main ways: by making sure more people understand what psychosis is, by training everyday professionals like family doctors, teachers, and emergency staff to spot the signs, and by improving how these professionals connect with specialist mental health services. The main goal of this study is to see if the PRESTO program can successfully reduce the DUP, meaning people get help much faster than they currently do.
Key takeaways
- Getting help quickly for a first episode of psychosis is very important.
- The study tests a program (PRESTO) to speed up access to specialist care.
- This could improve long-term health for people experiencing psychosis.
- It aims to educate the public and train frontline professionals.
- The study doesn't involve new medication, but focuses on early identification.
Who may be eligible?
This study is looking for young people aged 15 to 35 who have recently started experiencing symptoms of psychosis for the first time. You might be eligible if a doctor has diagnosed you with conditions like schizophrenia, schizoaffective disorder, schizophreniform disorder, or brief psychotic disorder, based on specific medical guidelines.
To be included, you shouldn't have received strong antipsychotic medication before for these symptoms, except possibly very recently for the current episode, and for no longer than six months. For all participants, if you're an adult, you'll need to give your permission to be part of the study. If you're under 18, your parents or guardians will need to give their permission.
However, you won't be able to join the study if you're already receiving ongoing treatment for a first episode of psychosis, or if your symptoms are very mild and don't require specific ongoing medical help.
Could this study suit you?
Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.
- Are you between 15 and 35 years old?
- Have you recently experienced your first episode of psychosis symptoms?
- Have you not had strong antipsychotic medication for these symptoms before, or only for a very short time (less than 6 months) for this recent episode?
- Have you not been receiving ongoing treatment for a first episode of psychosis already?
- Are your symptoms significant enough to require medical attention?
What does participation involve?
This study is focused on how quickly people get help, rather than a specific treatment. If you participate, you won't be given new medication as part of the study itself. Instead, the study will observe how the PRESTO program helps connect people to existing specialist care. This means there might be observations or assessments related to how quickly you access and engage with services, and possibly some questionnaires to understand your experience. The exact number of visits and the total duration would depend on the program's structure and your individual care plan, but the main intervention is about improving access to care, not a fixed treatment period.
Potential risks and benefits
Locations (6)
- Hospices Civils de LyonVerified postcodeBron, France· Recruiting
- Chu Clermont-FerrandVerified postcodeClermont-Ferrand, France· Recruiting
- Chu GrenobleVerified postcodeGrenoble, France· Recruiting
- CHU de MontpellierVerified postcodeMontpellier, France· Recruiting
- CHU de NîmesVerified postcodeNîmes, France· Recruiting
- Chu Saint EtienneVerified postcodeSaint-Etienne, France· Recruiting
Common questions
What is 'psychosis'?
Psychosis is a medical condition where someone's thoughts and perceptions become disturbed, and they might have difficulty telling what's real from what isn't.
What is 'Duration of Untreated Psychosis' (DUP)?
DUP is simply the length of time between when someone first shows clear signs of psychosis and when they start getting proper medical help for it.
Will I be given new medication in this study?
No, this study isn't about testing new medicines. It's about finding out if a program can help people get into existing specialist care sooner.
What is the PRESTO program?
The PRESTO program is an effort to help people with their first episode of psychosis get help quickly. It does this by informing the public, training professionals, and connecting different parts of the healthcare system.
Who is running this study?
This study is being conducted by researchers to understand how to improve early care for psychosis. More details would be provided by the study team.
How to find out more
Eric FAKRA, MD PhD
Always speak to your GP or specialist before deciding to take part in a study.
Interested in taking part?
Discussion
Community discussion
Powered by our forum at community.patient.info. Please be respectful — this is not medical advice.