A Study to Test Long-term Treatment With Brigimadlin in People With Solid Tumours Who Took Part in a Previous Study With This Medicine

This study is specifically for adults who have solid tumours and are already receiving brigimadlin as part of another research study sponsored by the same company. You need to be well enough to continue working with the study team and follow the study instructions.

Before joining, you'll need to sign a consent form, which means you understand what the study involves and agree to take part. Women who could become pregnant and men who could father a child must agree to use effective birth control throughout the study and for a period afterwards.

You would not be able to join if your doctor believes that taking brigimadlin would not be safe for you, or if you are pregnant, breastfeeding, or planning to become pregnant. Also, if you need to take other medicines that might interfere with brigimadlin or the study, you might not be able to participate.

If you decide to join this study, you will continue to take brigimadlin tablets once every three weeks. You will need to visit the study site for each dose. During these visits, the doctors and nurses will check your overall health, ask how you are feeling, and look for any unwanted effects the medicine might be causing. They will perform tests, which might include blood tests, and sometimes check the size of your tumour or whether it has spread.

There isn't a fixed end date for your participation; you will stay in the study for as long as the treatment appears to be helping you and you are able to tolerate it well. If the treatment isn't working for you or if the side effects are too much, you can stop participating. You will have regular appointments to ensure everything is going smoothly.