RecruitingNAINTERVENTIONAL

Effect of Daily Humiome® Post LB Intake on Wellbeing in Older Individuals With Moderate Stress Levels

This research, called "PostWelLB," aims to find out if a daily supplement called Humiome® Post LB can help reduce stress in adults aged 50 to 75. Scientists are interested in how components from tiny organisms in our gut might affect our overall mood and wellbeing. Participants will take either the Humiome® Post LB supplement or a 'dummy' pill (placebo) every day for three months. Neither the participants nor the researchers will know who is taking which substance until the study is over. The main goal is to see if those taking Humiome® Post LB report feeling less stressed compared to those taking the dummy pill. The study will take place in France.

At a glance

Status

Recruiting

Phase

Sponsor

dsm-firmenich Switzerland AG

Enrolment target

200

Start

01 Apr 2026

Estimated completion

01 Dec 2026

Stress

What is this study about?

This research study, named "PostWelLB," is investigating a daily supplement called Humiome® Post LB. The main goal is to see if taking this supplement for three months can help reduce stress levels in older adults, specifically those aged between 50 and 75.

Humiome® Post LB is a special product made from tiny, inactive organisms and their beneficial components, similar to how probiotics work but in a different way. It was developed from a product called Lactéol, which has been used safely for many years to help with tummy troubles. While Lactéol is known for aiding digestion, recent initial studies in animals suggest that Humiome® Post LB might also have a positive effect on mood and stress. This fits with growing ideas that our gut health can influence how we feel mentally.

The researchers want to test this idea in people because stress can become more common as we get older. Participants will be divided into two groups: one will receive the Humiome® Post LB supplement, and the other will receive a 'dummy' pill called a placebo. Neither the participants nor the doctors involved will know who is getting what until the study ends. This helps ensure fair and accurate results.

Key takeaways

The study tests a daily supplement (Humiome® Post LB) for stress in older adults.
It uses a 'dummy pill' (placebo) for fair comparison.
Participation lasts about 3 months, taking one capsule daily.
It's for people aged 50-75 with moderate stress levels.
The supplement comes from a product with a good safety record.
The goal is to see if it helps reduce stress and improve wellbeing.

Who may be eligible?

To join this study, you need to be a man or woman between 50 and 75 years old and live in France. Your body weight should be healthy for your height (your BMI should be between 18.5 and less than 30). You should also be experiencing a moderate level of stress, which will be measured by a questionnaire.

For women, you should not be pregnant or at risk of becoming pregnant. If you are still able to have children, you must be using effective contraception. If you have been through menopause, you shouldn't be using hormone replacement therapy, or you should have stopped it at least three months ago.

You cannot join the study if you have certain health conditions like diabetes, thyroid problems, high blood pressure (unless they are well-managed for a while), severe long-term illnesses like cancer, kidney problems, or serious digestive diseases. You also need to agree to keep your usual diet and exercise habits during the study and have access to a smartphone or computer for filling out study forms.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you between 50 and 75 years old?
Do you have a healthy weight for your height (BMI between 18.5 and less than 30)?
Are you currently experiencing moderate stress?
For women: Are you not pregnant, not at risk of pregnancy, and/or are you menopausal and not on recent hormone therapy?
Do you generally feel healthy and don't have certain serious or unmanaged long-term health conditions?
Do you have a smartphone or computer to complete study forms?

Answer every question to see your result.

What does participation involve?

If you decide to join this study, you would take a capsule every day for 12 weeks (about three months). These capsules will contain either the Humiome® Post LB supplement or a placebo (a dummy pill). The capsules are made from plant materials and contain a small amount of a common ingredient called magnesium stearate. You will have regular contact with the study team, likely through online forms or possibly some in-person visits to check on your health and progress. You'll be asked to maintain your usual lifestyle (diet and activity) throughout the study. The total duration of your active participation, including follow-up, will be around three months.

Potential risks and benefits

Taking part in this study might offer a potential benefit if the Humiome® Post LB supplement helps reduce your stress levels and improves your overall wellbeing. However, there's no guarantee you will experience any benefit, especially if you receive the placebo. All participants are closely monitored, and the supplement being tested comes from a product with a long history of safe use. As with any study, there's always a small chance of unexpected effects, although these are considered unlikely given the nature of the product. Remember, you can choose to leave the study at any time, for any reason, without it affecting your medical care.

Locations (1)

Biofortis
Verified postcode
Saint-Herblain, France· Recruiting

Common questions

What is Humiome® Post LB?

It's a daily supplement derived from inactive tiny organisms and their healthy components, similar to probiotics, that may help with wellbeing.

What is a 'placebo'?

A placebo is a 'dummy' pill that looks just like the real supplement but doesn't contain any active ingredients. It helps researchers compare results fairly.

How long will the study last if I join?

You would take the supplement or placebo for about three months (12 weeks).

Will I know if I'm taking the real supplement or the dummy pill?

No, neither you nor the study team will know until the study is finished, which helps keep the results unbiased.

What if I have other health conditions?

Certain health conditions might prevent you from joining. The study team will review your medical history carefully to ensure it's safe for you to participate.

How to find out more

Eleonora Rossi, PhD

eleonora.rossi@biofortis.fr +33 240205799 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.