RecruitingNAINTERVENTIONAL

PICO 7 vs PICO 14 in Revision Hip and Revision Knee Surgery.

This study is comparing two types of advanced dressings called PICO 7 and PICO 14, used on surgical wounds. It focuses on patients who are having a second (revision) hip or knee surgery. The main goal is to find out if using these dressings for 7 days is just as good as using them for 14 days, especially when surgery is done in areas that have been operated on before. Researchers want to understand which length of time helps the wound heal best and reduces problems later on. Patients will be randomly placed into one of the two groups, receiving either the 7-day or 14-day treatment, to help answer this important question.

At a glance

Status

Recruiting

Phase

Sponsor

Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust

Enrolment target

164

Start

14 Feb 2024

Estimated completion

14 Feb 2027

Surgical Wound

What is this study about?

Imagine you've had hip or knee surgery, and later on, you need another operation in the same area—this is called revision surgery. After any surgery, keeping the wound clean and helping it heal well is really important. This study is looking at special dressings called PICO dressings, which use a gentle suction to help wounds heal.

We know these dressings are good at helping wounds get better, but what we don't know is how long they should stay on, especially after revision surgery where the skin might have scarred from the first operation. Some doctors believe 7 days might be enough, while others think 14 days could be better to prevent problems like delayed wound healing. This study wants to find the best answer by comparing these two treatment times.

By taking part, you would help doctors understand the best way to use these dressings for patients having revision hip or knee surgery. This could help future patients heal better and reduce the chance of complications. You would be helping to improve care for people just like you.

Key takeaways

Compares 7-day vs. 14-day special dressings after hip/knee revision surgery.
Aims to improve wound healing and reduce complications.
You'll be randomly assigned to one of two treatment groups.
Requires follow-up visits to check your recovery.
Helps doctors find the best duration for these dressings.
You can stop participating at any time.

Who may be eligible?

To join this study, you need to be at least 18 years old and scheduled for a repeat hip or knee surgery that isn't due to an infection. It's important that you're able to come to all the necessary follow-up appointments and follow the instructions given by the study team.

However, some people won't be able to join. If your revision surgery is because of an infection, or if you have a history of not following medical advice, you wouldn't be suitable. Also, if you know you're allergic to any parts of the PICO dressing (like certain glues or materials), then this study wouldn't be right for you.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you 18 years old or older?
Are you having hip or knee revision surgery (not due to infection)?
Are you able to attend all planned follow-up appointments?
Are you not allergic to sticky dressings or similar materials?
Do you not have a history of struggling to follow medical advice?

Answer every question to see your result.

What does participation involve?

If you decide to take part, you'll be randomly assigned to one of two groups: either you'll use the PICO dressing for 7 days (PICO 7) or for 14 days (PICO 14). After your hip or knee revision surgery, the special dressing and a small pump will be put on your wound. If you're in the 7-day group, the dressing will be changed to a standard one after one week. If you're in the 14-day group, you'll have one dressing change after a week, where the pump will be briefly stopped and then restarted with a new dressing for another week of treatment. You'll also need to attend a few follow-up visits to the hospital outpatient department so the research team can check on your wound healing and overall recovery. The total duration of your active participation would involve the dressing application period and your follow-up appointments.

Potential risks and benefits

Taking part in this study could help us learn more about the best way to heal wounds after revision surgery, potentially benefiting future patients. While PICO dressings are generally well-tolerated, there's a small chance of allergic reactions to the dressing materials, and all surgeries carry general risks. You are free to withdraw from the study at any time without affecting your medical care.

Locations (1)

Some site locations are approximate. We're improving this — please verify with the trial team before travelling.

Robert Jones & Agnes Hunt Orthopaedic Hospital NHS Foundation Trust
Verified postcode
Oswestry, United Kingdom· Recruiting

Common questions

What is 'revision surgery'?

Revision surgery means having a second operation on your hip or knee, usually because the first replacement needs to be fixed or replaced again.

What is an 'NPWT PICO dressing'?

It's a special dressing that uses a gentle vacuum (negative pressure) to help your wound heal by drawing out fluid and promoting healthy tissue growth.

Will I know which dressing group I'm in?

You will be randomly assigned to either the 7-day or 14-day dressing group, so it will be decided by chance, like flipping a coin.

What happens after the dressing is removed?

After the study dressing period, if you were in the 7-day group, a standard dressing will be applied. Your surgical team will continue to monitor your wound healing during your follow-up appointments.

Will this cost me anything?

No, your participation in the study, including the dressings and necessary follow-up visits specifically for the study, will not cost you anything.

How to find out more

Julie Steen, BSc. (Hons)

julie.steen@nhs.net 01691404210 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.