All studies
CompletedInterventional

Shifting the practice and attitude of private doctors with respect to unethical benefits from pharmaceutical companies for prescribing medicines

In many parts of the world, private doctors may receive gifts or financial perks from drug companies to encourage them to prescribe certain medicines. This can lead to patients receiving antibiotics they do not need, which increases the risk of superbugs that standard medicines cannot treat. This study, led by the London School of Hygiene and Tropical Medicine, tests a new training programme for family doctors in Karachi, Pakistan. The training focuses on medical ethics, rules, and understanding conflicts of interest. Doctors in the study take part in educational seminars, receive regular reminder messages, and have their prescribing reviewed. Researchers hope to see whether teaching doctors about professional ethics helps them make better prescribing choices. The ultimate goal is to improve the quality of patient care and protect vital antibiotics for the future.

At a glance

Status
Completed
Sponsor
London School of Hygiene & Tropical Medicine
Enrolment target
280
Start
01 Sep 2021
Estimated completion
31 Mar 2022

What is this study about?

Antibiotics are life-saving medicines used to fight bacterial infections. However, when they are taken too often or prescribed when they are not needed, bacteria learn to survive them. This creates antibiotic resistance, turning treatable infections into dangerous threats. In some healthcare systems, drug companies offer bonuses or perks to private doctors who prescribe their products. When money or gifts influence medical decisions, it is called a conflict of interest, and it can mean patients get medicines they do not truly need.

This clinical study is exploring how to tackle this problem at its root. Researchers from the London School of Hygiene and Tropical Medicine are testing a special ethics programme for family doctors in Karachi, Pakistan. Because many people in Pakistan rely on private clinics for their everyday care, changing how these doctors prescribe antibiotics could have a huge positive impact on public health.

Rather than just teaching basic science, this study focuses on professional values, duty of care, and identifying hidden incentives. By understanding what drives prescribing choices and teaching doctors how to handle commercial pressure, the researchers hope to build stronger ethical standards. Ultimately, this work aims to safeguard patient health and help keep antibiotics working for everyone.

Key takeaways

  • The study tests an ethics training programme for private family doctors in Pakistan.
  • It aims to reduce commercial incentives that lead to unnecessary antibiotic prescriptions.
  • Preventing overprescribing helps fight the global threat of antibiotic resistance.
  • Participating doctors attend seminars and receive regular reminder messages.
  • The study does not involve testing any new drugs on patients.

Who may be eligible?

This study is designed specifically for healthcare professionals rather than members of the general public. To join, a person must be a qualified medical doctor (holding an MBBS degree) registered with the Pakistan Medical Council, currently working as a general practitioner in a private primary care clinic in Karachi.

Doctors cannot take part if they only work in large referral hospitals, work solely as specialist consultants, or run charitable welfare clinics. Non-allopathic practitioners, such as alternative or complementary medicine providers, are also not eligible.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

  1. You are a fully qualified medical doctor with an MBBS degree.
  2. You are registered with the Pakistan Medical Council (PMC).
  3. You work as a primary care general practitioner (GP) in Karachi.
  4. You do not work exclusively in hospital-based or specialist consultant roles.
  5. You do not run a charitable welfare clinic.
Answer every question to see your result.

What does participation involve?

Because this is an educational study, taking part does not involve receiving medicines or undergoing medical procedures. Participating family doctors attend continuing medical education seminars focused on professional ethics, conflicts of interest, and official guidance on prescribing. After the training, doctors receive brief reminder messages directly to help keep the key ideas fresh in their minds. The research team also carries out unannounced quality assessments to see how doctors prescribe in everyday practice and to provide helpful, private feedback. The overall project ran from June 2021 to July 2022.

Potential risks and benefits

Taking part does not involve physical health risks or medical hazards. Participating doctors benefit by learning up-to-date ethical guidance, strengthening their professional standards, and discovering how to give their patients the highest quality of care. Their involvement also helps researchers design better policies to protect healthcare systems worldwide. Doctors can decide to leave the study at any time without giving a reason, simply by contacting the research team.

Locations (2)

  • London School of Hygiene and Tropical Medicine
    Approximate
    London, England
  • Aga Khan University
    Approximate
    Karachi, Pakistan

Common questions

Why is this study focusing on antibiotics?

Overusing antibiotics causes bacteria to become resistant, making everyday infections much harder to treat. Ensuring doctors only prescribe them when necessary protects everyone's health.

Can patients join this trial?

No. This trial is only open to qualified family doctors practicing in private clinics in Karachi, Pakistan.

Does this study involve testing any new medicines?

No. The study only tests an educational training programme and reminder messages for doctors; no experimental medicines are given out.

What is a conflict of interest in healthcare?

It happens when a doctor's medical decisions might be influenced by secondary benefits, such as gifts, money, or perks from pharmaceutical companies.

Who is funding this research?

The research is funded by UK organisations, including the Foreign, Commonwealth & Development Office, the Wellcome Trust, the Medical Research Council, and the Economic and Social Research Council.

How to find out more

Mishal Khan

Always speak to your GP or specialist before deciding to take part in a study.

Discussion

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