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Analysis of the Functional Impact of Total Knee Arthroplasty Using Quantified Gait Analysis and Proprioceptive Evaluation

This study focuses on people who have a total knee replacement because of painful knee arthritis (gonarthrosis). While knee replacement surgery is very common and usually works well, about 1 in 10 patients are still not happy with their results. We want to find out why this happens. Researchers will use special tools to measure how people walk and move before and after their knee surgery. They will also look at how patients feel about their new knee and how well they can do everyday tasks. By comparing these results, the study hopes to discover what factors might lead to poorer outcomes and dissatisfaction, even after a successful operation. This information could help improve knee replacement surgery for everyone in the future.

At a glance

Status
Not yet recruiting
Sponsor
University Hospital, Grenoble
Enrolment target
15
Start
01 Apr 2025
Estimated completion
01 Oct 2027

What is this study about?

Knee replacement surgery is a very common and effective way to treat severe knee arthritis, a condition where the tough, slippery cartilage in your knee wears away, causing pain and stiffness. This surgery involves replacing the damaged parts of your knee with artificial ones, often made of metal and plastic. While many people have great results, about 10 out of every 100 people who have a knee replacement are still not completely happy with how their knee feels or works afterward. Even though surgical methods have improved a lot, we don't fully understand why some people are still dissatisfied.

This study aims to discover why some people don't get the best results from their knee replacement. We will closely examine how people move and use their new knee. This includes using special equipment to accurately measure walking patterns and checking how well patients can sense the position of their knee (proprioception) both before and after surgery. We'll also ask patients directly about their experiences and how well they can perform daily activities, like getting up from a chair.

By carefully comparing all this information – how people move, their physical sensations, and their personal feedback – the researchers hope to pinpoint the reasons why some patients might not be fully satisfied after their knee replacement surgery. The goal is to learn more about how knee replacements affect daily life, ultimately helping to improve surgery outcomes and patient satisfaction for future patients.

Key takeaways

  • Aims to understand why some patients are unhappy after knee replacement.
  • Uses special tests to measure walking and knee sensation before and after surgery.
  • Collects patient feedback on daily activities and satisfaction.
  • Does not change your planned knee replacement surgery.
  • Hopes to improve future outcomes for knee replacement patients.

Who may be eligible?

To join this study, you need to be an adult who has severe knee arthritis (gonarthrosis) that doctors have said needs a full knee replacement. This means your arthritis should be mainly in your knee, and your doctor thinks surgery is the next step for you.

There are also some reasons why you might not be able to join. For example, if you have other health conditions that affect your balance or how you sense your body's position, like Parkinson's disease or effects from a stroke, you wouldn't be able to participate. Also, if you have problems with your memory or thinking, or if you can't walk without help for at least six months, or struggle to get up from a chair without using your arms, this study might not be right for you. Your ability to do daily tasks independently will also be checked.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

  1. Are you an adult (18 years or older)?
  2. Have you been diagnosed with severe knee arthritis requiring total knee replacement?
  3. Do you have good balance and no other conditions affecting it (like Parkinson's)?
  4. Can you walk without special walking aids for at least 6 months?
  5. Can you get up from a standard chair without using your arms?
Answer every question to see your result.

What does participation involve?

If you decide to take part in this study, the researchers will closely monitor your knee and how you move, both before and after your total knee replacement surgery. You will likely have several appointments where specific tests will be carried out. These tests will include a 'quantified gait analysis,' which uses special sensors to measure your walking patterns very precisely. You might also perform certain everyday tasks, and your ability to sense your knee's position (proprioception) will be checked.

These assessments will happen before your surgery and again at specific times afterward. You'll also be asked to share your thoughts and feelings about your knee's function and your overall satisfaction. The study typically involves a period before surgery, the surgery itself, and then follow-up assessments for several months to understand the long-term impact. There won't be any new medications prescribed specifically for the study; it focuses on evaluating the effects of your planned surgery.

Potential risks and benefits

Taking part in this study might help us learn more about why some people aren't fully satisfied after knee replacement surgery, which could lead to better outcomes for others in the future. There are no direct medical benefits to you personally beyond your planned surgery. The main 'risk' is the time commitment for the extra assessments and appointments, which might be inconvenient. Some physical assessments might involve slight discomfort, similar to what you might experience in a physical therapy session. Remember, joining is completely voluntary, and you can withdraw from the study at any time without affecting your medical care.

Locations (1)

  • Grenoble University Hospital
    Verified postcode
    Grenoble, France

Common questions

What is 'gonarthrosis'?

It's the medical term for severe arthritis in the knee, where the smooth cartilage wears away, causing pain and stiffness.

What does 'quantified gait analysis' mean?

It means using special equipment and sensors to accurately measure how you walk, including things like your stride length and how your joints move.

What is 'proprioceptive evaluation'?

It's a test to see how well you can sense the position and movement of your knee, even when you can't see it.

Will I have different surgery if I join this study?

No, you will have the same total knee replacement surgery as planned by your surgeon. This study just involves extra tests before and after.

How long will I be in the study?

The study will track your progress before surgery and for a period afterwards to see how your knee recovers and functions over time.

How to find out more

Always speak to your GP or specialist before deciding to take part in a study.

Interested in taking part?

Register your interest

Share your details and the research team for "Analysis of the Functional Impact of Total Knee Arthroplasty…" will contact you if you may be eligible. Always speak to your GP before agreeing to take part.

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