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Splenic Embolisation Decisions

When people have an accident, their spleen can sometimes get injured and bleed. Doctors can stop this bleeding either with a big operation or a smaller procedure called splenic embolisation, which involves blocking the bleeding blood vessel through a small cut in the leg. We don't fully understand which method is best for different types of spleen injuries, or why the smaller procedure isn't always used. This study uses information from a large database of trauma patients in the UK to help answer these questions. By looking at how different injuries were treated and what happened to patients, we hope to find out the best ways to treat spleen injuries and improve care for people in the future.

At a glance

Status
Recruiting
Sponsor
University Hospital Plymouth NHS Trust
Enrolment target
8,000
Start
22 Jul 2024
Estimated completion
30 Sep 2026

What is this study about?

Imagine you've had an accident and hurt your belly, and doctors find that your spleen, an organ that helps your blood, is bleeding. Doctors have a couple of main ways to stop this bleeding. One is a bigger operation where they open up your tummy. The other is a smaller procedure called splenic embolisation. For this, they make a tiny cut, usually in your groin, and thread a very thin tube (like a straw) through a blood vessel to reach your spleen. Then, they block the bleeding bit to stop it.

Now, here's the thing: doctors aren't always sure which of these ways is best for every type of spleen injury. Sometimes, even when the smaller procedure could work, it isn't used, and we don't know why. Also, there are a few different ways to do the smaller procedure, and it's not clear which one works best. This study aims to clear up some of these unknowns.

To do this, researchers are looking at a huge collection of patient information called the Trauma and Audit Research Network (TARN) database. This database has lots of details about people who've had serious injuries in the UK. By carefully looking at this existing information, along with some other medical records, the study hopes to find patterns and answers. This will help doctors understand exactly when and how to use splenic embolisation, or whether a different approach is better, to give everyone the best possible care for spleen injuries.

Key takeaways

  • This study uses existing medical records, not new patient involvement.
  • It aims to improve treatment decisions for spleen injuries after accidents.
  • Researchers are comparing different ways to stop bleeding from the spleen, including a less invasive procedure.
  • The study uses information from a large UK database of trauma patients.
  • Findings could help doctors choose the best treatment for future patients with spleen injuries.

Who may be eligible?

This study is looking back at information from patients who have already been treated. This means you won't be actively taking part in the study yourself, so there are no specific eligibility checks for you to make or appointments to attend.

However, the study is interested in information about any patient who had a spleen injury from an accident between January 1, 2016, and December 31, 2020. They need to have enough information in the TARN database, including a CT scan report that clearly graded their spleen injury.

The study will not look at information from patients if there isn't a CT scan available to properly grade their spleen injury. Otherwise, they are looking at information from all adults, regardless of their age (over 18) or sex.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

  1. Did you have a spleen injury from an accident?
  2. Was this injury between 2016 and 2020?
  3. Are you 18 years old or older?
  4. Was your spleen injury diagnosed with a CT scan that graded the injury?
Answer every question to see your result.

What does participation involve?

As this study is looking back at existing medical records and data from a large database (TARN), you will not be asked to participate directly. There will be no visits, assessments, medication, or follow-up involved for any patients. The researchers are simply analysing anonymous information that has already been collected, so there is no direct patient involvement or duration of participation for individuals.

Potential risks and benefits

Since this study only analyses existing, anonymised patient data, there are no direct risks or benefits to individual patients because you are not actively participating in any medical procedures or treatments. The potential benefit is for future patients, as the findings could lead to better decisions and improved care for people with spleen injuries. Because there is no active participation, there is no right to withdraw as an individual patient.

Locations (1)

Some site locations are approximate. We're improving this — please verify with the trial team before travelling.
  • University Hospitals Plymouth NHS Trust
    Verified postcode
    Plymouth, United Kingdom· Recruiting

Common questions

What is the spleen and why is it important?

The spleen is an organ in your belly that helps filter your blood and fight infections. It can sometimes get injured in accidents.

What is splenic embolisation?

It's a way to stop bleeding from the spleen by blocking a blood vessel, usually done through a small cut in your leg, without needing a big operation.

Why is this study being done?

Doctors want to understand when the smaller procedure (splenic embolisation) is best for spleen injuries, and when a bigger operation might be better, to improve future patient care.

Will my personal medical information be used?

No, the study uses anonymous information from a large database. Your personal details will not be identified.

How will this study help patients?

By understanding the best treatments for spleen injuries, doctors can make more informed decisions, potentially leading to safer and more effective care for people who have accidents.

How to find out more

Always speak to your GP or specialist before deciding to take part in a study.

Interested in taking part?

Register your interest

Share your details and the research team for "Splenic Embolisation Decisions…" will contact you if you may be eligible. Always speak to your GP before agreeing to take part.

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