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Ongoing, recruitingHuman Pharmacology (Phase I)- OtherInterventional

A clinical research study investigating how the body processes the new compound petrelintide in people with kidney problems

This research study is investigating a new medication called petrelintide, which is being developed to help with weight management. The main goal of this particular study is to understand how a person's body processes and uses petrelintide, especially if they have kidney problems. This is an early phase of research, sometimes called "Human Pharmacology," which means it's one of the first times this new medicine is being tested in people. Researchers want to learn more about how the drug works in the body before it can move on to larger studies. The study welcomes adults aged 18 and over, of all genders. There is no detailed description provided about the study at this time beyond its focus on understanding how the body handles the new compound.

At a glance

Status
Ongoing, recruiting
Phase
Human Pharmacology (Phase I)- Other
Sponsor
Zealand Pharma A/S
Enrolment target
48
Start
14 Mar 2025

What is this study about?

This study is looking into a new medication called petrelintide, which is being explored as a potential treatment to help people manage their weight. The main aim of this research is to see exactly how your body takes in, uses, and gets rid of petrelintide. This is particularly important for people who also have kidney problems, as kidneys play a big part in how medicines are processed.

This is a very early-stage study, sometimes called a "Phase I" or "Human Pharmacology" study. This means it's one of the first times this new medicine is being tested in people. At this stage, doctors are not yet looking for the medicine to treat an illness. Instead, they want to understand fundamental things like how safe it is, what dose might be right, and how it behaves inside the body. This information is crucial before the medicine can be tested in larger groups of people for its effectiveness.

By taking part, you would be helping doctors and scientists learn more about petrelintide and whether it could be a safe and effective option for weight management in the future. The results from studies like this are vital for developing new medicines that could help many people.

Key takeaways

  • Investigating a new medicine, petrelintide, for weight management.
  • Specifically focuses on how petrelintide works in people with kidney issues.
  • This is an early-stage study (Phase I) to understand safety and how the body handles the drug.
  • Open to adults aged 18 and over, of all genders.
  • Participation involves medical checks, taking the study drug, and regular clinic visits.

Who may be eligible?

To join this study, you need to be an adult, 18 years old or older. The study is open to both men and women.

The main focus of this study is on people who have kidney problems. While the brief information doesn't give specific details about the type or severity of kidney problems, it's a key factor for taking part. You would also need to be looking into weight management.

Before you can join, the study doctors will chat with you and do some checks to make sure the study is a safe and suitable option for you. This is to protect your health and ensure the study collects the right information.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

  1. Are you 18 years old or older?
  2. Do you have kidney problems?
  3. Are you interested in weight management?
  4. Are you able to attend regular clinic appointments?
Answer every question to see your result.

What does participation involve?

If you decide to take part, the study team will first talk with you to explain everything in detail and answer your questions. You'll then go through a screening process, which will involve medical checks like blood tests and a physical exam, to make sure you're suitable for the study.

Once enrolled, you would receive the study medication, petrelintide. It's likely this would involve regular visits to the clinic for medical assessments, blood samples to see how your body is handling the medicine, and to check your overall health. The exact number of visits, how often they are, and the total length of your participation haven't been detailed, but the study team would explain all of this clearly before you agree to join. There will also be follow-up appointments after you stop taking the medication to ensure you are well.

Potential risks and benefits

Participating in research always involves potential benefits and risks. A potential benefit could be contributing to medical science and helping develop new treatments for weight management, especially for people with kidney problems. You might also have more frequent medical check-ups than usual. However, there are potential risks, such as side effects from the new medication, which are currently unknown and will be monitored closely. There could also be discomfort from blood tests or other procedures. You are always free to withdraw from the study at any time, for any reason, without it affecting your usual medical care.

Locations (1)

Some site locations are approximate. We're improving this — please verify with the trial team before travelling.
  • Unverified
    Germany

Common questions

What is petrelintide?

Petrelintide is a new medication being tested to see if it can help with weight management.

Why are kidneys mentioned?

The study specifically wants to see how the body processes petrelintide in people who have kidney problems, as kidneys are important for how medicines work in the body.

Is this medicine guaranteed to help me lose weight?

No, this is an early stage study, so doctors are mostly learning how the medicine works in the body and its safety, not yet focusing on its effectiveness for weight loss.

Will I have to pay to be in the study?

No, you should not have to pay to take part in a clinical trial. All study-related care and medication are usually covered by the study sponsor.

How long will the study last for me?

The exact length of your participation will be explained by the study team, as it varies between studies. They will tell you before you commit.

How to find out more

Always speak to your GP or specialist before deciding to take part in a study.

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