RecruitingNAINTERVENTIONAL

Comparison of MI Paste Plus and Resin Infiltration in White Spot Lesions Following Orthodontic Treatment

Many people get white spots on their teeth after having braces. These spots can be the first sign of tooth decay and can make teeth look uneven. This study is testing and comparing two different treatments for these white spots. One treatment uses a special toothpaste called MI Paste Plus, which contains ingredients that help to strengthen tooth enamel. The other treatment is called resin infiltration, where a tooth-coloured material is soaked into the white spot to make it less noticeable and stronger. Researchers want to see which method is more effective at making these white spots disappear and preventing further damage, especially on the front teeth of young people who have just finished their orthodontic treatment.

At a glance

Status

Recruiting

Phase

Sponsor

University of Alberta

Enrolment target

Start

30 May 2023

Estimated completion

01 Oct 2026

White Spot Lesions Orthodontic Appliance Complication Caries Arrested Smooth Surface Caries

What is this study about?

When you have braces, it can sometimes be difficult to keep your teeth perfectly clean. This can lead to small, chalky-white patches appearing on the surface of your teeth, often called 'white spot lesions'. These spots are an early sign of tooth decay and can be quite noticeable, especially on your front teeth.

This study is looking at two ways to treat these white spots. One method uses a special paste called MI Paste Plus, which has ingredients that help to rebuild and strengthen the tooth enamel. The other method is called resin infiltration. This involves applying a special liquid material that soaks into the white spot, helping to fill in the weakened areas and making the spot blend in better with the rest of your tooth.

The main goal of this research is to compare these two treatments to see which one works best at making white spots less visible and stopping them from getting worse. We want to find the most effective way to help people who have just finished their braces treatment to have healthy, evenly coloured teeth. This is important because treating these spots early can prevent them from turning into larger cavities.

Key takeaways

Study compares two treatments for white spots after braces.
Treatments are MI Paste Plus and resin infiltration.
Aims to make white spots less visible and prevent further decay.
Focuses on young people aged 12-21.
Could help improve smile appearance and dental health.

Who may be eligible?

This study is looking for young people aged between 12 and 21 years old who have recently finished their treatment with fixed braces (not removable aligners).

To join, you must have at least one of these white spots on the front teeth, which means the spots can be on your upper or lower front teeth. You should also have fairly good brushing habits, but it's okay to have a little plaque.

However, you can't join if you have very poor brushing habits, or if you have other dental issues like naturally thin or discoloured enamel, or fillings on your front teeth. Also, if you had these white spots before you even started your braces, or if you've used any special re-mineralising toothpastes (other than regular toothpaste) in the last three months, you won't be able to take part. People with a milk allergy or any serious medical/mental conditions, or those who don't speak English, also won't be eligible.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you between 12 and 21 years old?
Have you recently finished treatment with fixed braces?
Do you have at least one white spot on a front tooth?
Do you have fairly good brushing habits?
Do you NOT have a milk allergy?
Have you NOT used special re-mineralising toothpastes in the last 3 months (other than regular toothpaste)?

Answer every question to see your result.

What does participation involve?

The detailed information about what taking part involves is not fully provided in this summary. However, based on similar studies, you would likely have a few appointments at the dental clinic. During these visits, the researchers would examine your white spots, take pictures, and then apply one of the two treatments (either MI Paste Plus or the resin infiltration). You would then likely have follow-up appointments over a period of time to see how well the treatment is working and if the white spots have improved. The total duration of your participation would depend on the follow-up schedule.

Potential risks and benefits

Taking part in this study could potentially help improve the appearance of the white spots on your teeth, which might boost your confidence. It also helps researchers understand which treatment works best, which could benefit many others in the future. As with any dental procedure, there might be some minor temporary discomfort during treatment. There's also a very small chance of an allergic reaction, though this is carefully checked beforehand. You are free to withdraw from the study at any time, for any reason, without it affecting your usual dental care.

Locations (1)

KAYE Edmonton Clinic
Verified postcode
Edmonton, Canada· Recruiting

Common questions

What are white spot lesions?

They are chalky-white patches on teeth, often seen after braces, indicating early tooth decay.

What is MI Paste Plus?

It's a special paste that helps strengthen tooth enamel and repair early decay.

What is resin infiltration?

It's a treatment where a special tooth-coloured liquid is soaked into the white spot to make it look better and stronger.

Will I know which treatment I get?

The information provided doesn't specify if you'd know. Often, in studies like this, participants might not know to keep the results fair.

Can I still get my teeth cleaned normally?

Yes, you should continue with your regular oral hygiene routine, including brushing your teeth.

How to find out more

Ida M Kornerup, DMD, MEd

kornerup@ualberta.ca 780 492 7100 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.