RecruitingInterventional

Comparing an easy-to-use swab test and ultrasound for detection of womb cancer

This study is looking into a new and simpler way to check for womb cancer in women who have unusual bleeding. Womb cancer can be hard to spot early, and the current main test, an ultrasound scan, can sometimes lead to extra, unnecessary procedures. Researchers want to compare a new swab test, called WID®-easy, with the standard ultrasound scan. They hope this new test will be better at finding womb cancer and could help reduce the number of invasive tests women need. The study will also gather information to see if the WID®-easy test could be used routinely across the NHS to help more women.

At a glance

Status

Recruiting

Sponsor

Sola Diagnostics UK Ltd

Enrolment target

2,000

Start

02 Mar 2026

Estimated completion

05 Nov 2026

Womb cancer

What is this study about?

Womb cancer (also known as endometrial cancer) is a type of cancer that affects the lining of the womb. The most common sign of womb cancer is unusual vaginal bleeding. However, it's important to remember that only a small number of women with unusual bleeding actually have womb cancer. Spotting womb cancer early can be tricky. The ultrasound scan, which is the test usually offered, isn't always accurate enough, meaning many women end up having more invasive tests that they don't necessarily need.

This study aims to find a better way to check for womb cancer. We are comparing the usual ultrasound scan with a new, easy-to-use swab test called WID®-easy. The main goal is to see how well the WID®-easy test works compared to the ultrasound. If it's more accurate, it could potentially help doctors detect womb cancer earlier and reduce the number of women who need to go through more uncomfortable tests.

Ultimately, the researchers hope to gather enough information to show that the WID®-easy test is a good option to be used routinely throughout the NHS. This could make diagnosing womb cancer quicker and less stressful for many women in the future.

Key takeaways

A new swab test (WID®-easy) is being compared to ultrasound for womb cancer.
The study aims to improve early detection and reduce unnecessary invasive procedures.
It's for women aged 45+ with unusual vaginal bleeding.
You will have both the new swab test and the standard ultrasound.
The study could help decide if this new test should be used in the NHS.
You can stop participating at any time.

Who may be eligible?

This study is looking for women aged 45 or older who have a womb and have been referred to a hospital because of unusual vaginal bleeding. You would also need to be happy to understand and sign a consent form to join the study.

Unfortunately, you wouldn't be able to take part in this study if you are currently pregnant or if you've already had your womb removed (a hysterectomy).

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you a woman aged 45 or older?
Do you have a womb?
Have you been referred to the hospital for unusual vaginal bleeding?
Are you currently not pregnant?
Have you *not* had your womb removed (a hysterectomy)?

Answer every question to see your result.

What does participation involve?

If you decide to take part, the study will involve collecting information about your health over a year. You will have the usual ultrasound scan that you would normally have for your symptoms. You will also have the WID®-easy swab test. If your WID®-easy test comes back positive, and your ultrasound didn't already suggest more tests were needed, you might be asked to come back for a follow-up appointment. This would involve a procedure called a hysteroscopy, where a thin camera is used to look inside your womb while you are asleep under general anaesthetic.

Researchers will collect information from you again at 3 months and 12 months after you join the study. Towards the end of your time in the study, you'll also have the chance to fill out an optional questionnaire about your experience. Some participants will also be asked if they'd like to share more feedback in a one-on-one chat. The study is expected to run from February 2026 to May 2028.

Potential risks and benefits

A direct potential benefit of joining this study is that the WID®-easy test might be able to spot womb cancers that the usual ultrasound scan could miss. It's important to know that with any medical test, including the standard ultrasound, there's a small chance of getting a 'false' result (either saying you have something when you don't, or saying you don't when you do). If the WID®-easy test gave a false negative result, we would expect you to continue having symptoms and you would then go back to your doctor. You are free to withdraw from the study at any time without giving a reason, and this would not affect your medical care.

Locations (4)

University College London Hospital
City only
London, England
Royal Free Hospital
Approximate
London, England
Barnet Hospital
Approximate
Barnet, England
North Middlesex Hospital
Approximate
London, England

Common questions

What is womb cancer?

Womb cancer, also known as endometrial cancer, is a type of cancer that starts in the lining of the womb.

What is the WID®-easy test?

It's a new, simple swab test being compared to ultrasound for finding womb cancer.

Will I still have an ultrasound scan?

Yes, all women in the study will have the standard ultrasound scan as part of their care.

What happens if the WID®-easy test is positive?

If it's positive and the ultrasound didn't already show a problem, you might be asked to come back for a further test called a hysteroscopy.

Who is paying for this study?

The study is funded by the National Institute for Health and Care Research (NIHR) in the UK.

How to find out more

Sara Sleigh

sleigh@sola-diagnostics.com +43 (0)676 9037365 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.