Acute Kidney Injury research hub

MEMRI and Kidney Disease

This study uses a special MRI scan to look at how kidney injury, kidney transplants, and other kidney problems affect your heart. Researchers want to find a new way to identify people at risk of heart problems and ongoing kidney disease, helping them get treatment earlier.

Pilot Study on HA380 Column Use in Critically Ill Patients Receiving Extracorporeal Support.

This study looks at a special blood filter, HA380, for very sick patients in intensive care. It's connected to machines like dialysis or ECMO to see if it can help them recover faster by reducing the body's overreaction to illness.

A Study to Support the Development of the Enhanced Fluid Assessment Tool for Patients With Acute Kidney Injury

This study aims to create a better tool for doctors and nurses to check fluid levels in hospital patients with sudden kidney problems (AKI). Currently, it's hard to tell if patients have too much or too little fluid. This new tool could help them get the right care.

LoW Dose-Intensity vs. Standard Dose-Intensity COntinuous Renal ReplaceMent Therapy in Critically Ill Patients (WISDOM)

The WISDOM trial is looking into how much dialysis critically ill patients with severe kidney problems need. It compares the usual amount of dialysis with a lower amount to see if less is just as good, safer, and maybe even better for recovery and hospital costs.

A Study to Investigate the Efficacy, Safety, and Tolerability of AZD4144in Participants With Sepsis-associated Acute Kidney Injury.

This study looks at a new medicine called AZD4144 for people who have kidney damage from a serious infection (sepsis). We want to see if it's safe and helps their kidneys work better than a dummy medicine.

The Rhabdomyolysis Evaluation in the Emergency Department (REED) Score

This study looks at older adults (60+) who fall and stay on the floor for a long time. It aims to create a tool to predict who might get a serious muscle breakdown condition called rhabdomyolysis and need hospital care, helping doctors decide who can safely go home.

Urine Alkalinisation in COVID-19

This study looks at whether a simple treatment called sodium bicarbonate can protect the kidneys of very sick COVID-19 patients. We know kidney problems are common with severe COVID-19. This research wants to see if making blood less acidic might help prevent this serious issue.

The Effect of Vasopressor Therapy on Renal Perfusion in Septic Shock

This study looks at how different medicines, like vasopressin and angiotensin II, affect blood flow to the kidneys in very unwell patients with a serious infection called septic shock. We want to see if these medicines can help improve kidney function when it's failing.

Efficacy and tolerance of nicotinamide supplementation during acute kidney injury: a prospective randomized double-blind trial

This study is testing if a vitamin called nicotinamide can help people with sudden kidney problems (acute kidney injury) recover better. Researchers will give some patients nicotinamide and others a dummy pill to see if it improves their kidney function after 21 days.

Improving Patient Assessment After Acute Kidney Injury (AKI)

This study aims to improve care for people after acute kidney injury (AKI). It looks at better ways to measure kidney function and understands patients' experiences to suggest new ways to support them. Participants may have blood tests, body scans, and interviews.

A randomized, multi-centric, placebo-controlled, participant and investigator-blinded study to evaluate the safety, tolerability and efficacy of TIN816 in adult patients at risk for acute kidney injury following cardiac surgery