- recruiting
Improving Sedation Practice in Critically Ill Adult Patients Using a Co-designed Sedation Protocol
This study aims to improve how medication for pain and relaxation (sedation) is given to very ill patients on life support (ECMO). We want to create a new guide based on patient, family, and staff experiences to help these patients recover better.
United Kingdom - recruitingNA
HONEY for the Treatment of POst-Tonsillectomy Pain
This study is looking at whether Manuka honey can help reduce pain after tonsil surgery in adults. Researchers want to see if it's a good, simple, and affordable option to manage discomfort, compared to a sugar syrup.
United Kingdom - not yet recruitingNA
Feasibility of Protocolised Analgosedation in ECMO
This study looks at whether a special plan for giving painkillers and sedatives (drugs to help you relax) to very sick patients on a life support machine called ECMO could lead to better long-term health. It's testing if such a study is possible to run.
United Kingdom - enrolling by invitation
Conversion of Labor Analgesia for Intrapartum Cesarean Delivery: DPE v CSE v Epidural
This study looks at different ways to give pain relief during labour (epidural, DPE, CSE) and how well they work if a C-section is needed. It aims to see if newer methods make it easier to use the same pain relief for surgery.
United States · Canada - recruitingPHASE2
A Randomized Comparison Between 0.67 mcg/kg, 1 mcg/kg, and 1.33 mcg/kg of Perineural Dexmedetomidine for Ultrasound-Guided Infraclavicular Block
This study is looking at different doses of a medicine called dexmedetomidine, given with pain numbing medicine for arm surgery. We want to see if a higher dose helps the numbing medicine work for longer, especially for movement in the hand and fingers.
Canada - not yet recruiting
Postoperative Analgesia Using a Perineural Catheter Versus a Single Nerve Block in Rearfoot Surgery
This study looks at how well a special pain-relief tube (perineural catheter) works after foot surgery, compared to a single pain-blocking injection. It aims to see if the tube reduces pain better and helps people recover faster, using information from routine care.
France - enrolling by invitation
Longitudinal Assessment of Pain-Related Patient-Reported Outcomes After Surgery
This study looks at how people feel in the first few weeks after surgery, especially regarding pain. It aims to understand pain, how it affects daily life, and if signs of nerve pain appear early on, to help improve care after patients go home.
Germany · Mexico - recruitingPHASE1
Nebulized Fentanyl in Healthy Volunteers
This study is looking at a new way to give strong pain relief (fentanyl) using a face mask or nose spray, rather than needles, especially for emergencies. It aims to see if it's safe and comfortable, and how well the medicine gets into the body.
France