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RecruitingNAINTERVENTIONAL

HONEY for the Treatment of POst-Tonsillectomy Pain

This study is investigating if Manuka honey can help adults feel less pain after a tonsillectomy (surgery to remove tonsils). Tonsillectomy is a common operation, and recovery can be quite painful, sometimes leading to other problems. While standard painkillers work, they can have side effects. Researchers are comparing Manuka honey to a plain sugar syrup to see if the honey is effective in managing pain. This is a double-blind, randomised study, meaning neither the participants nor the researchers will know who is getting the honey and who is getting the syrup. The aim is to find out if Manuka honey could be a helpful, low-cost option for pain relief after tonsil surgery, building on traditional uses and recent suggestions about its benefits.

At a glance

Status
Recruiting
Phase
NA
Sponsor
East and North Hertfordshire NHS Trust
Enrolment target
100
Start
04 Sep 2023
Estimated completion
04 Sep 2025

What is this study about?

Tonsil surgery, known as a tonsillectomy, is a very common operation in the UK. While it helps many people, recovering from it can be quite painful, especially for adults. This pain can sometimes make it difficult to eat or drink enough, which might even lead to needing to go back to the hospital, getting an infection, or bleeding.

Currently, doctors use various painkillers like paracetamol, ibuprofen, and throat sprays. Sometimes, stronger pain relief like opioids (such as codeine or tramadol) are needed. Although these can be effective, they can also cause side effects like constipation, sleepiness, or feeling sick, and aren't usually recommended for long-term use. This is why doctors are always looking for other ways to help people manage their pain after surgery.

This study is exploring whether Manuka honey could be a useful option. Honey has been used for healing for thousands of years, and Manuka honey in particular is known to have properties that fight bacteria and reduce swelling. It's even used in some NHS hospitals for treating burns and skin wounds. Researchers want to see if applying Manuka honey after tonsil surgery can help reduce pain more effectively than a simple sugar syrup, and if it could be a safe, affordable, and easily available way to help you feel better during recovery.

Key takeaways

  • The study tests Manuka honey for pain after tonsil surgery.
  • It aims to find a simple, low-cost pain relief option.
  • Adults having tonsil surgery are eligible.
  • You might receive honey or a plain sugar syrup.
  • You'll still get your usual pain medication.
  • You can stop participating at any time.

Who may be eligible?

This study is looking for adults aged 18 or over who are scheduled to have a tonsillectomy operation. You need to be having a bilateral tonsillectomy (both tonsils removed) or an adenotonsillectomy (tonsils and adenoids removed) within the study period.

There are some reasons why you might not be able to take part. For example, if you are pregnant, have diabetes, or are allergic to bee products or golden syrup, you won't be able to join. Also, if you currently experience chronic (long-lasting) pain, have fibromyalgia (a condition causing widespread body pain), or have had certain types of cancer or radiotherapy in your head or neck area, you would not be eligible.

To ensure the study is safe and effective for everyone involved, the research team will carefully check all these points with you before you can take part.

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

  1. Are you 18 years old or older?
  2. Are you scheduled to have both tonsils removed, or tonsils and adenoids, very soon?
  3. Do you have diabetes or a history of long-term pain?
  4. Are you allergic to bee products or golden syrup?
  5. Are you pregnant?
Answer every question to see your result.

What does participation involve?

If you decide to take part in this study, you will essentially be asked to use either Manuka honey or a sugar syrup after your tonsillectomy, alongside your usual painkillers. This will be done for a set period during your recovery at home. The study is 'double-blind,' meaning neither you nor the researchers will know whether you are receiving the active Manuka honey or the sugar syrup. You will be given clear instructions on how and when to use the study product. There will likely be some follow-up and monitoring to see how you are recovering and how your pain is managed, which might involve questionnaires or check-ins. The total duration of your participation will cover your recovery period following the surgery.

Potential risks and benefits

Taking part in this study might benefit you by potentially providing better pain relief after your tonsillectomy, or helping you recover more smoothly, should Manuka honey prove effective. However, there's no guarantee it will work for everyone, and you might receive the sugar syrup instead of the honey. While Manuka honey is generally safe, there's a small risk of allergic reaction for those sensitive to bee products. You will continue to receive standard medical care and pain relief throughout the study. Remember, you can choose to withdraw from the study at any time without affecting your medical care.

Locations (1)

Some site locations are approximate. We're improving this — please verify with the trial team before travelling.
  • Lister Hospital
    Verified postcode
    Stevenage, United Kingdom· Recruiting

Common questions

What is a 'double-blind' study?

It means neither you nor the research team giving you the syrup will know if you're getting the Manuka honey or the plain sugar syrup. This helps ensure fair and unbiased results.

Why Manuka honey?

Manuka honey has properties that fight bacteria and reduce swelling, and it's been used for wound healing. Researchers want to see if these properties can also help with pain after tonsil surgery.

Will I still get my usual painkillers?

Yes, you will continue to receive all the standard pain relief medications prescribed by your doctor during your recovery, alongside the study treatment.

What if I feel worse during the study?

Your medical team will be closely monitoring you. If you feel worse or have any concerns, you should always contact your healthcare provider, just as you would normally after surgery.

Is this study safe?

The study has been carefully reviewed for safety. You will only be included if it's considered safe for you, and you'll be monitored throughout.

How to find out more

Carina Cruz

Always speak to your GP or specialist before deciding to take part in a study.

Interested in taking part?

Register your interest

Share your details and the research team for "HONEY for the Treatment of POst-Tonsillectomy Pain…" will contact you if you may be eligible. Always speak to your GP before agreeing to take part.

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