Autism spectrum disorder research hub

A randomized, placebo-controlled, double-blind, 2-period cross-over study in youth with autism spectrum disorders evaluating social and repetitive behaviors after four weeks of twice daily-doses of 24IU of intranasally administered oxytocin

This study looks at how a nose spray with a substance called oxytocin might affect social skills and repetitive behaviours in young people with autism over four weeks. We want to see if it makes a difference.

Environmental Influence on Mental Illness Via Modifications of Genomes and Metabolomes in Adolescents With Autism

This study looks at how the environment affects mental health in autistic teenagers. Researchers want to understand why some autistic young people develop mental health conditions and how to offer them more personalized support. They will study genes and body chemicals to find clues.

A Game-based Neurodevelopmental Assessment for Young Children

This study is testing a new tablet game for children aged 3-8 years to help quickly and accurately spot developmental differences like ADHD or autism. It compares the game's results with other assessments to see if it's a reliable new tool.

Investigating the Clinical Utility of the Oxford Virtual Autism Assessment Tool (OVAAT)

This study is testing a new online tool, the Oxford Virtual Autism Assessment Tool (OVAAT), to see how well it can spot signs of autism in young people aged 13-18. Researchers want to know if it's as good as or better than existing assessments.

Complementary & Integrative Healthcare for Children With Autism: A Pilot Study

This study looks at how online tools can help assess complementary therapies for children with autism. It aims to see if these therapies might improve symptoms and if a larger study would be possible. Children aged 3-12 with certain autism symptoms might be able to take part.

Proof of Concept Study on Pitolisant Effect on Autism Spectrum Disorders in Children and Adolescents

This study is looking into a new medication called Pitolisant for boys aged 6 to 17 with Autism Spectrum Disorder (ASD). It aims to see if Pitolisant helps manage ASD symptoms and if it's safe to use, compared to a dummy pill.

Purrble's Soothing Touch for Eating Disorders and Autism

This study looks at how a cuddly device called Purrble might help people on the waiting list for eating disorder treatment. It aims to see if Purrble can help with managing emotions, sensory feelings, and anxiety while they wait to start therapy.

Assessment of the Usability/acceptability of the Little Journey App by Parents/guardians/legal Representatives and Children Aged Between 3-12 Years Old Who Have a Diagnosis of Autism Spectrum Disorder (ASD).

Impact of Sulphonylureas on Neurodevelopmental Outcomes in KCNJ11-related Intermediate Developmental Delay, Epilepsy and Neonatal Diabetes (iDEND) Syndrome

This study looks at how a diabetes medicine, sulphonylurea, affects brain development in children and adults with a specific genetic condition called iDEND syndrome. We want to see if starting this medicine early in life leads to better developmental outcomes.

CFT Guided Self-help Intervention: Parents of Autistic Children

This study is testing a new self-help program for parents of autistic children aged 6-17. It uses compassion-focused techniques to help parents manage stress and improve their well-being. It's guided and involves workbooks and audio.

Brain Imaging in Babies Study

This study looks at how babies' brains develop from before birth until they are 3-4 years old. Researchers use safe brain scans and check children's behaviour to understand brain growth. They also want to see if they can predict conditions like autism and ADHD early on, and how COVID-19 might affect brain development.

Effect of faecal microbiota transplant on the expression of autism spectrum disorder core symptoms in children – open-label phase II clinical trial (FMT-PAS)

This study is exploring if a special treatment called a faecal microbiota transplant (FMT) can help reduce some core symptoms of autism in children. It's a Phase II trial, meaning it's still an early stage of testing to see how well it works and if it's safe.