- recruitingTherapeutic use (Phase IV)
Evaluation of the effect of para-sternal block on postoperative respiratory function after sternotomy cardiac surgery. Prospective, controlled, randomized, single-blind study with independent assessment of outcome
This study looks at how a pain-blocking injection, called a para-sternal block, affects breathing after heart surgery. Researchers want to see if it helps people breathe better and feel less pain after their operation.
France - completed
A clinical trial comparing how well two solutions protect the heart during heart surgery in children
This UK study compares two protective fluids used during children's heart surgery. When surgeons repair heart defects, they temporarily stop the heart using a special liquid. Researchers want to find out whether a fluid called del Nido helps children recover faster and with fewer complications compared to the standard UK fluid, St. Thomas'.
United Kingdom · England - not yet recruiting
Does a prehabilitation programme help people prepare for heart surgery? A feasibility study
Heart surgery can save lives, but recovery takes time. The Fit4HeartOp study looks at whether a personalised preparation programme helps NHS patients get ready for heart surgery. It offers gentle exercise, nutrition advice, and emotional wellbeing support, whether you are waiting at home or already in hospital.
United Kingdom · England - recruitingPHASE2
LSALT Peptide for Prevention or Attenuation of Acute Kidney Injury (AKI) in Patients Undergoing On-Pump Cardiac Surgery
This study looks into a new treatment called LSALT peptide to help prevent or reduce kidney damage in people having heart surgery. It compares LSALT with a dummy treatment to see if it's safe and effective.
Canada · Turkey (Türkiye) - not yet recruiting
SURgical Registry of ENDocarditis EuRope
This study is gathering information from adults across Europe who have a heart infection called infective endocarditis and are having heart surgery. It aims to understand current treatments and how patients recover in both the short-term and long-term.
Germany - recruitingPHASE3
Reducing Cardiac-surgery Associated Acute Kidney Injury Occurence by Administering Angiotensin II
This study is looking at whether a medicine called Angiotensin II can help protect kidneys during heart surgery. We want to see if it reduces the chance of kidney problems compared to a standard medicine, Noradrenalin, in adult patients undergoing bypass or valve surgery.
Germany - not yet recruitingPHASE1, PHASE2
Influence of Lung Volume Optimization Maneuver on Cardiac Output and Lung Compliance in Ventilated Children With Congenital Heart Disease Undergoing Surgical Repair
This study looks at how adjusting breathing machines could help children with heart problems after surgery. We're testing a special way to manage lung pressure to see if it makes their hearts and lungs work better.
Germany - recruitingNA
Diagnosis of Postoperative Atrial Fibrillation by a Smartwatch
This study looks at how smartwatches can help spot an irregular heartbeat called atrial fibrillation after heart surgery. It aims to see if these watches can find issues quickly, especially when patients are no longer in intensive care, helping doctors to act sooner.
France - recruiting
CARE Qualitative Study
This study looks into why some people return to hospital after heart surgery. Researchers want to understand what care is currently given and what changes could help patients stay well at home, reducing the need for readmission. It aims to improve support for people after they leave hospital.
United Kingdom - not yet recruitingNA
Transversus Thoracic Plane Block for Perioperative Analgesia in Cardiac Surgery
This study looks at a special pain-blocking injection, called a Transversus Thoracic Plane Block, for people having heart surgery. Researchers want to know if it reduces pain better than usual care and if it works best before or after the operation.
Lebanon - not yet recruitingNA
Prehabilitation Program for Patients Awaiting Elective Heart Surgery at Increased Risk of Postoperative Complications: Feasibility and Potential Clinical Outcomes
This study looks at whether a special exercise programme before heart surgery helps people at higher risk of problems recover better. Participants follow an exercise plan and breathing exercises at home, with weekly physio support. The aim is to see if this is safe and helpful.
Canada - recruitingNA
Exploring if Patients Can Safely and Easily Swab Their Own Surgical Wounds at Home
This study looks at whether people who've had heart surgery can safely and easily take their own wound swabs at home. The aim is to see if this helps check for infections without needing hospital visits.
United Kingdom - recruitingNA
Transfusion Requirements in Younger Patients Undergoing Cardiac Surgery
This study looks at different ways of giving blood transfusions to younger patients (under 66) having heart surgery. It compares two common approaches to see which one is safer and more effective. The goal is to improve care for people undergoing these operations.
United States · Australia · Canada - active not recruiting
Age Related Chromatin Remodelling as a Therapeutic Target for Organ Protection in Cardiac Surgery
This study looks into why people with long-term health issues often have problems after heart surgery. We're trying to understand how ageing affects heart cells and makes surgery recovery harder, hoping to find new ways to protect organs.
United Kingdom - recruitingNA
Exercise Prehabilitation in Congenital Heart Disease
This study looks at whether a tailored exercise plan before heart surgery can help adults born with heart problems recover better. Patients will either receive usual care or a supervised exercise program. The goal is to see if exercise improves fitness and is practical to offer before surgery.
United Kingdom