- not yet recruiting
Development of the Drug and Alcohol Respiratory Health Test
This study is creating a simple test to check lung health in adults who use certain substances. Many people with substance use disorder have breathing problems that often go unnoticed. This new test aims to find these issues early so people can get the right help.
United Kingdom - active not recruitingNA
Evaluation of the Safety and Efficacy of TLD in Patients with COPD
This study is looking at a new treatment called Targeted Lung Denervation (TLD) for people with a lung condition called COPD. It aims to see if TLD is safe and works better than standard care to reduce flare-ups of COPD symptoms.
United States · Austria · France - recruitingNA
Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3
This study looks at a new treatment called Apreo BREATHE for people with severe emphysema, a type of COPD. It tests if inserting small devices into airways can help release trapped air and improve breathing, alongside usual care.
United States · Austria · Netherlands - recruiting
Study of Inflammatory and Physiological Profiles of Healthy and Diseased Lung
This study looks at how lung diseases like asthma and COPD affect the body. Researchers want to understand these conditions better by studying samples from healthy people and those with lung problems to find better ways to help patients.
United Kingdom - recruitingNA
Structured Review: To Optimise Management and Prevent Harm in COPD
This study aims to help people with COPD who have frequent flare-ups. We want to improve their treatment, check for other health problems, and reduce how often they need steroid tablets, which have side effects. It’s a thorough health check to help you feel better.
United Kingdom - recruitingPHASE2
Effects of Blocking TSLP on Airway Inflammation and the Epithelial Immune-response to Exacerbation Triggers in Patients With COPD
This study is looking at a new medicine called tezepelumab for people with COPD. It aims to see if this medicine can help reduce inflammation in the airways and prevent flare-ups of their condition.
Denmark · United Kingdom - active not recruiting
COPD Case Finding In Nottingham and District: C-FIND COPD A Pilot Study
This study in Nottingham checks for a lung condition called COPD in people already having a lung health scan. It uses breathing tests and aims to find COPD early, as spotting it late means more lung damage. Participants will also get health advice.
United Kingdom - recruitingPHASE2
A Study to Evaluate Solrikitug in Participants With COPD (ZION)
This study is testing a new medicine, Solrikitug, for people with a lung condition called COPD. Researchers want to see if different doses are safe and how they affect the body and COPD symptoms compared to a dummy medicine.
United States · Australia · Canada - not yet recruiting
The AcCREDiT 2 Study
The AcCREDiT 2 study looks at how to quickly identify infections in people with breathing problems, like pneumonia or flare-ups of conditions like COPD. It aims to improve how we test for these infections and make sure patients get the right treatment faster.
United Kingdom - recruiting
The Use of Entropy to Assess Sleep Disordered Breathing in Chronic Respiratory Disease
This study looks at breathing problems during sleep in people with long-term lung conditions like asthma or COPD. Researchers are using a new way to analyse sleep study data to better understand how these conditions affect sleep and breathing.
United Kingdom - authorisedTherapeutic use (Phase IV)
Erdosteine effect on oxidative stress, inflammatory response and immune modulation in patients with COPD. A single center, open label, double arm, controlled, 4-week, explorative, ex vivo study.
This study looks at how a drug called erdosteine affects the body's defence systems and inflammation in people with COPD. Researchers will compare those taking erdosteine plus usual care to those on usual care alone over four weeks.
Italy - active not recruitingNA
Symptoms and Functions in Patients With COPD and Chronic Bronchitis Switching From CIG to THS
This study looks at how people with lung disease (COPD) who smoke feel and function when they switch from regular cigarettes to heated tobacco products (THS). It aims to see if switching can improve symptoms like cough and breathlessness, and help their lungs work better.
United States · Bulgaria · Czechia - recruiting
The Clear Conversations Project
This project, called 'Clear Conversations', helps healthcare staff improve how they talk to patients. The aim is for patients with conditions like COPD or those managing their weight to better understand their health info, feel more in control, and get better results.
United Kingdom - recruitingPHASE3
Supported Rescue Packs Post-discharge in Chronic Obstructive Pulmonary Disease
This study looks at a new way to help people with COPD stay out of hospital after a flare-up. It tests if a 'supported rescue pack' plan, including medicine, a self-management guide, and phone support, works better than usual care to reduce hospital readmissions.
United Kingdom