Healthy Participants research hub

The Effect of Ketone Monoesters on Skeletal Muscle Protein Synthesis and Whole-body Protein Metabolism.

This study looks at how a special drink called a ketone monoester, taken with protein, affects muscle growth and repair in healthy young adults. We want to see if it can help muscles get stronger and recover better.

A Study of Absorption, Distribution, Metabolism and Excretion (ADME) of [14C]AZD4144

This study in Nottingham is looking for healthy men aged 30-65. It aims to understand how a new medicine moves through the body, how it's broken down, and if it causes any side effects. We'll track it using a tiny amount of carbon-14.

A Study to Investigate Andexanet Dosing and the Interaction Between Andexanet and Subsequent Enoxaparin in Healthy Participants

This study is testing a new medicine called Andexanet. It's for healthy people aged 18 to 55. We want to see how Andexanet works with common blood thinners like Rivaroxaban and Apixaban, and if it affects another blood thinner called Enoxaparin. This helps doctors understand how to use Andexanet safely.

Do Daily Disposable Soft Contact Lenses Require Frequent Checks After the Initial Fitting is Complete in Adults Under 40 With No Contraindications

This study looks at whether adults under 40 who wear daily disposable contact lenses really need lots of check-up appointments after their first fitting. Researchers want to find out the best number of visits. We're interested in healthy people new to lenses or who already wear them.

A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD1043 in Healthy Adult Participants Living With Overweight and/or Obesity.

This study is looking into a new medication called AZD1043 for people who are overweight or have obesity. Researchers want to understand if it's safe, how the body handles it, and how it affects the body.

A Study to Assess the Relative Bioavailability of Different Subcutaneous Formulations ofAZD6234

This study looks at how a new medicine, AZD6234, gets into the body when given in different ways. It aims to find the best way to give the medicine and check for any side effects in healthy people.

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of UCB5285 in Healthy Study Participants

This study is looking into a new medicine called UCB5285. We want to see if it's safe and how the body handles it in healthy people, including those of Japanese background. It's an early-stage study to understand the medicine better.

Study of TGM-312-SC01 in Healthy Participants and Adults With MASH

A Study to Evaluate the Safety, Pharmacokinetics, and Occurrence of Anti-Drug Antibodies Following Annual Doses of CD388

This study looks at the new drug CD388 in healthy adults. It checks if taking it once a year for two years is safe and how your body reacts to it, especially if you had a good experience with it before. Researchers also want to see if your body makes substances that fight the drug.

A Study to Investigate the Safety and Pharmacokinetics of Single- and Multiple-ascending Doses of AZD4916 in Healthy Volunteers

This study is looking at a new medicine called AZD4916 in healthy adults. Researchers want to check if it's safe and how it moves through the body after taking different doses, both once and multiple times.

Non-invasive Ultrasonic Auricular Vagus Nerve Stimulation

This study looks at a new, gentle way to stimulate a special nerve called the Vagus nerve using sound waves instead of electricity. It aims to see how this affects healthy people's bodies and minds, hoping to find new ways to help with conditions like anxiety or depression in the future.

A study to learn if UCB3101 is safe and how it moves through the body of healthy participants

Effect of Modafinil on military observational performance and residual capacity of the Dutch Air Assault Brigade: a field trial

AN OPEN-LABEL, RANDOMIZED STUDY TO EVALUATE THE RELATIVE BIOAVAILABILITY OF A NEW TABLET FORMULATION OF MINZASOLMIN AND THE POTENTIAL EFFECT OF FOOD ON THE PHARMACOKINETICS OF MINZASOLMIN IN HEALTHY PARTICIPANTS