- ongoing, recruitingHuman Pharmacology (Phase I)- Other
Tramadol Administered Orally to Healthy Subjects for the Improvement of its Detection in Biological Matrices in the Context of Anti-Doping Control
This study is looking at how the painkiller tramadol can be found in people's bodies. We need healthy volunteers to take tramadol so scientists can improve tests used in sports to detect it. This helps make sure competitions are fair and safe.
Spain - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
A Single Dose, Fed state, Crossover Replicate Bioequivalence Study of NITROFURANTOIN 100 mg prolonged-release capsules (Iasis Pharma) vs. FURABID® 100 mg prolonged-release capsules (Amdipharm Limited)
This study is comparing two versions of a 100mg nitrofurantoin capsule, a medicine used for bladder infections, in healthy people. It wants to check if a new version works the same way as an existing one, to make sure it's just as effective and safe.
Romania - active not recruitingNA
The Critical Link Between Gut Microbiome Dysfunction, Cravings and Relapse: RECLAIM-GUT TRIAL
This study looks at how your gut's tiny living bugs might affect cravings and alcohol use. Researchers are testing special food supplements (prebiotics) designed just for you, to see if they can help improve your gut health and, in turn, your overall well-being. It's for healthy adults who drink alcohol moderately.
United Kingdom - ongoing, recruitingHuman Pharmacology (Phase I)- First administration to humans
A research study of a new medicine (NNC0650-0013) in healthy men
This study is looking for healthy men to test a new medicine for the first time. The medicine might help with weight and type 2 diabetes. It's an early-stage study to see how safe it is and how it works in the body.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
A Single Dose, Fast State, Bioequivalence Study of CEFIXIMA ATB 400 mg Hard Capsules (Antibiotice S.A.) vs. CEFIXORAL® 400 mg Film Coated Tablets (A. Menarini Industrie Farmaceutiche Riunite s.r.l.)
This study is checking if two different versions of a medicine, both containing 400mg of Cefixime, work the same way in the body. It involves healthy adult volunteers and looks at how the medicine is absorbed and cleared.
Romania - ongoing, recruitingTherapeutic use (Phase IV)
Rivaroxaban sotorasib interaction study (the ROSIE-study)
This study is looking at how two medicines, sotorasib (LUMYKRAS) and rivaroxaban (Xarelto), interact when taken together. Researchers want to see if taking sotorasib affects how much rivaroxaban stays in your body and for how long. It involves healthy volunteers.
Netherlands - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
A Single Dose, Fasting state, Crossover Replicate Bioequivalence Study of Naproxen 500 mg/Esomeprazole 20 mg, modified-release tablets (Antibiotice S.A.) vs. Vimovo® 500 mg/20 mg film-coated tablets (Grunenthal Gmbh)
This study compares a new naproxen and esomeprazole tablet to an existing one. It checks if they work the same way in healthy people. This helps make sure new medicines are just as good as older, approved ones.
Romania - recruitingPHASE1
A Phase 1 Study of GTX-B001 in Healthy Subjects and Patients With Chronic Inducible Urticaria
This study is looking at a new medicine called GTX-B001 for people with constant a particular type of hives called chronic inducible urticaria (like cold hives or hives from scratching). It aims to check if the medicine is safe and if it helps reduce symptoms.
Germany - recruitingPHASE1
This is a Phase 1, Randomized, Single-blind, Placebo-controlled Study to Assess the Safety, Pharmacokinetics (PK), and Pharmacodynamics (PD) of BEAM-103 in Healthy Subjects
This study is testing a new medicine called BEAM-103 in healthy volunteers to see if it's safe. We'll also check how the body handles the medicine and how it affects blood. It's a first step to understand this potential new treatment.
United Kingdom - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
A Single Dose, Fast state, Crossover Replicate Bioequivalence Study of NITROFURANTOIN 100 mg prolonged-release capsules (IASIS PHARMA) vs.FURABID® 100 mg prolonged-release capsules (Amdipharm Limited)
This study compares a new version of the antibiotic nitrofurantoin (IASIS PHARMA) with the existing Furabid® for treating bladder infections. It checks if both medicines release into the body in the same way, using healthy volunteers. This is a standard early check for new medications.
Romania - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
A Single Dose, Fed state, Crossover Replicate, Bioequivalence Study of Naproxen 500 mg/ Esomeprazole 20 mg modified-release tablets (Antibiotice S.A.) versus Vimovo® 500 mg/20 mg film coated tablets (Grunenthal GmbH)
This study compares a new naproxen and esomeprazole tablet to an existing one called Vimovo. We want to see if the new tablet works in the body the same way as Vimovo. This helps ensure new medicines are just as effective.
Romania - authorisedHuman Pharmacology (Phase I)- Bioequivalence Study
A randomized, balanced, two-treatment, two-sequence, single oral dose, two stage crossover adaptative bioequivalence study of Rifaximin 200 mg film-coated tablets (Antibiotice SA) vs. Normix® 200 mg, film- coated tablets (Alfasigma S.P.A) in healthy subjects under fed conditions
This study compares two versions of a 200mg rifaximin tablet to see if they work the same way in the body. It involves healthy adults taking a single dose of each tablet, with food, to ensure they're equally effective. It's an important step before a new medicine can be widely used.
Romania - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
A Single Dose, Two – stage, Fasting State, Bioequivalence Study of Rifaximin 200 mg, film-coated tablets (Antibiotice S.A.) vs. Normix® 200 mg, film-coated tablets (Alfasigma S.p.A)
This study is testing if a new version of the antibiotic rifaximin (200mg tablets) works in the same way as the original, approved version. We are looking for healthy adults to take part. It helps ensure new medicines are just as effective and safe as current ones.
Romania