- ongoing, recruitingHuman Pharmacology (Phase I)- Other
A Study to evaluate the effect of a high-fat meal on the Pharmacokinetics of the Selective MET kinase Inhibitor DO-2 in subjects in good health
This study is looking at how a new medicine, called DO-2, is handled by the body when someone eats a fatty meal. It's for healthy adults and is an early stage of testing to learn more about the medicine.
Netherlands - active not recruitingPHASE1
A Study to Learn About the Safety of BIIB115 Injections and How BIIB115 is Processed in the Bodies of Healthy Adult Male Volunteers and of Pediatric Participants With Spinal Muscular Atrophy Who Previously Took Onasemnogene Abeparvovec
This study looks at a new medicine called BIIB115 for spinal muscular atrophy (SMA). It first tests the medicine's safety in healthy men, then in children with SMA. Researchers want to understand how safe BIIB115 is and how the body handles it.
Belgium · Canada · France - ongoing, recruitingHuman Pharmacology (Phase I)- Other
A study to investigate the bioavailability of the SAR444656 test formulation and the food effect on the SAR444656 test formulation in healthy adult participants
This study is looking at how a new medicine, SAR444656, gets into your body and whether eating food changes how it works. We need healthy adults to help us understand this better, as part of the early stages of testing new drugs.
Belgium - authorisedHuman Pharmacology (Phase I)- First administration to humans
An open-label, single-center study to evaluate the safety and test-retest characteristics of [11C]MODAG-005 as PET radioligand for imaging pathological alpha-synuclein deposition in the brains of patients with Parkinson’s disease (PD) or Multiple System Atrophy (MSA) compared to age-matched healthy controls (AMHC)
This study looks at a new way to see unusual protein build-up in the brains of people with Parkinson's and Multiple System Atrophy. It uses a special scan to help doctors understand these conditions better and work towards new treatments.
Germany - ongoing, recruitingHuman Pharmacology (Phase I)- Bioequivalence Study
Randomised, relative bioavailability clinical trial of amylmetacresol, dichlorobenzyl alcohol, lidocaine and vitamin c lozenges after a single oral dose administration to healthy volunteers under fasting conditions in a crossover design.
Spain - ongoing, recruitingHuman Pharmacology (Phase I)- Other
Pharmacology of nasal applied mupirocin in healthy volunteers: single-centre study. MUPIPHARM STUDY
France