- ongoing, recruitingTherapeutic use (Phase IV)
Phase IV, Randomized, Multicenter, Double-Blind Clinical Trial Designed to Evaluate the Safety and Appropriateness of Switching from DTG/3TC to BIC/FTC/TAF in People With HIV, Good Virological Control, and Neuropsychiatric Vulnerabilities: MIND Study
This study is looking at how switching HIV medication might affect your mood, thinking, and sleep. It's for people with HIV who are doing well on their current treatment but might have some brain-related symptoms. Researchers want to see if switching to Biktarvy is safe and helpful.
Spain - ongoing, recruitingPhase III and phase IV (Integrated)
DTG/3TC vs BIC/FTC/TAF maintenance therapy in people living with HIV: an open-label randomized clinical trial
This study compares two common HIV treatments, Biktarvy and Dovato, to see if they are equally good at keeping the virus under control. Researchers want to find out if Dovato is as effective as Biktarvy in maintaining a very low amount of HIV in the blood.
Spain - authorisedPhase III and phase IV (Integrated)
MENPI: Safety and immunogenicity following meningococcal and pneumococcal immunization among adult people living with HIV. A single center, non-blinded, randomized clinical trial
This study looks at how safe and effective vaccines are for meningitis and pneumonia in adults with HIV. It checks how their bodies react and whether the vaccines protect them well. It's a key step to improving health for people living with HIV.
Denmark - enrolling by invitation
EuroSIDA - Clinical and Virological Outcome of European Patients Infected With HIV
The EuroSIDA study looks at how HIV affects people in Europe and how treatments work over time. It helps us understand health changes and the impact of new medicines for HIV and related conditions like hepatitis.
Argentina · Austria · Belarus - active not recruitingPHASE3
A Study to Evaluate the Efficacy, Safety, and Tolerability of Using an Oral Once-daily 2 Drug Regimen Compared to an Oral Once-daily 3 Drug Regimen for the Treatment of Human Immunodeficiency Virus (HIV)-1 in Adults Who Have Not Previously Taken Antiretroviral Therapy
This study looks at two different daily pill combinations for adults newly diagnosed with HIV. It compares a two-drug treatment with a three-drug treatment to see which is safer and works better for controlling the virus.
Argentina · Belgium · Denmark - recruiting
The Role of Ectopic Fat and Heart Attack Risk in HIV
This study looks at how HIV affects fat storage around organs like the heart and liver. We're using MRI scans to understand why people with HIV might have a higher risk of heart attacks and how reducing this fat could help.
United Kingdom - recruitingPHASE2
Combination Vaccination and Broadly Neutralising Antibody Therapy in HIV
This study explores new ways to control HIV without daily medication. It combines special vaccines and powerful new antibodies to see if they can help the body fight off the virus long-term, aiming to reduce the need for lifelong daily treatments.
United Kingdom - recruitingNA
#AWARE.HIV Europe: Supporting Healthcare Professionals to Find Undiagnosed HIV in European Hospitals: An Effectiveness-implementation Trial.
This study looks at whether dedicated HIV teams in hospitals can increase HIV testing for specific health problems linked to HIV, aiming for earlier diagnosis and better health. It involves hospitals across Europe.
Belgium · France · Germany