- recruitingTherapeutic confirmatory (Phase III)
Double-Blind, Placebo-Controlled, Phase 3 Study to Evaluate the Efficacy and Safety of Plozasiran in Adults with Hypertriglyceridemia (MUIR-3 Study)
This study tests a new injection called plozasiran in adults with high levels of blood fats, known as triglycerides. Researchers want to see if plozasiran can safely lower these fats over one year compared to a dummy jab (placebo). This could help reduce risks to the heart and pancreas.
Slovakia · France · Czechia - recruitingPHASE1
A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias
This study is testing a new medicine called CTX310 for people in the UK with high cholesterol and fats in their blood that haven't improved with usual treatments. It will check if the medicine is safe and how well people tolerate different doses. It's an early-stage study.
United States · Australia · New Zealand - active not recruitingNA
WB-EMS Effects on Cardiometabolic Risk Factors
This study looks at how a type of exercise called whole-body electrical stimulation (WB-EMS) affects blood pressure and other health factors in men over 50. It wants to see if this quick, joint-friendly exercise can help people with slightly high blood pressure.
Germany - active not recruitingPHASE3
Phase 3 Study of Plozasiran in Adults With Hypertriglyceridemia
This study looks at a new injection called plozasiran for adults with high triglycerides. We want to see if it's safe and helps lower triglyceride levels compared to a dummy injection.
United States · Argentina · Australia - active not recruitingPHASE3
Long-Term Safety and Efficacy of Plozasiran in Adults With Hypertriglyceridemia
This study is testing a new injection called Plozasiran for adults with very high triglyceride levels. Participants have already been in related studies and will receive the injection every three months for two years, while following a low-fat diet.
United States · Argentina · Australia - recruitingPHASE1
Phase 1b Study of VERVE-201 in Patients With Refractory Hyperlipidemia
This study is testing a new treatment, VERVE-201, for people with very high cholesterol and fats in their blood that haven't responded to other medicines. Scientists want to see if it's safe and how it affects these blood fats by altering a specific gene in the liver.
United States · Australia · Canada