Ischemic Heart Disease research hub

Controlled Trial of High-risk Coronary Intervention With Percutaneous Left Ventricular Unloading

This study looks at a small heart pump used during a common heart procedure called a stent. It aims to see if this pump helps high-risk patients avoid serious complications and if it's good value for money.

Ultimaster Nagomi™ Sirolimus Eluting Coronary Stent System in Complex PCI Patients

This study looks at how well a special new heart stent, called Ultimaster Nagomi™, works in people with complex heart problems. It aims to see if it helps reduce serious issues like heart attacks or needing another procedure after one year.

Predicting the Risk of Non-culprit Coronary Artery Disease After a Heart Attack

ISCHEMIA-CTO Trial - Revascularisation or Optimal Medical Therapy of CTO

This study looks at whether opening blocked heart arteries, called CTOs, in people with heart disease works better than just using medicines. It aims to see if it improves major health problems, or quality of life for patients.

Optical Coherence Tomography in Acute Vessel Evaluation

This study compares two ways to help people having a heart attack: one uses standard X-rays, the other uses a special camera called OCT. We want to see if the OCT camera leads to better results for patients.

The OCTOBER Trial - European Trial on Optical Coherence Tomography Optimized Bifurcation Event Reduction (OCTOBER)

This study compares two ways to unblock heart arteries using stents for complex cases. It looks at whether using a special scanning tool, called OCT, during the procedure leads to better results over two years than standard methods.

Study on Optimal Temperature During Cardiopulmonary Bypass (THERMIC-4)

This study looks at the best body temperature during heart surgery using a heart-lung machine. Some doctors cool patients, while others keep them at normal temperature. We want to see if a normal temperature is a safe option for adult heart patients and if this type of study can be run effectively.

Colchicine Assessment of Low-grade Inflammation and Biomarker Response in Atherosclerosis with Targeted Evaluation

This study is looking at whether a common medicine called colchicine can reduce inflammation in the blood vessels of people with heart disease. We want to see if it helps improve heart health by using special scans to check for changes.

Distal Evaluation of Functional Performance with Intravascular Sensors to Assess the Narrowing Effect: Guided Physiologic Stenting

This study compares different ways to guide treatments for blocked heart arteries. It looks at whether using special wires that measure blood flow inside the heart's arteries helps doctors place stents better than traditional X-ray pictures. It aims to improve how we treat heart disease.