Distal Evaluation of Functional Performance with Intravascular Sensors to Assess the Narrowing Effect: Guided Physiologic Stenting

To join this study, you generally need to be an adult man or woman who is having a procedure called a cardiac catheterisation because you have chest pain, unstable angina, or a type of heart attack (NSTEMI). Your doctor must also think that a procedure to open up a blocked artery (called PCI) is needed in at least one of your heart arteries.

There are also certain reasons why you wouldn't be able to join. For example, if you've had a severe heart attack (STEMI) very recently, or if you've had a previous heart bypass surgery. You also can't participate if you've recently had a stent fitted or if your symptoms are only silent (meaning you don't feel them) and not related to coronary artery disease. Other reasons might include severe heart failure, very fast or irregular heartbeats that aren't controlled, or if you're in cardiogenic shock (a very serious heart condition).

If you join this study, you'll be randomly assigned to one of two groups: one where your stent procedure is guided by traditional X-ray pictures, or one where it's guided by the new pressure wire technology. Both procedures are designed to open up blocked heart arteries. The study will involve regular check-ups and tests, just like you would normally have after a heart procedure, to see how you're recovering and how well the treatment worked. The exact number of visits and tests will be explained to you in detail, but they are generally part of standard care. The total duration of your participation in the study will also be clearly outlined.