- recruitingNA
RESTORE - Study of AGN1 LOEP to Prevent Secondary Hip Fractures
This study, called RESTORE, looks at a new treatment (AGN1 LOEP) to help prevent a second hip fracture in older women who have already had one. Researchers want to see if this treatment, given after the first hip fracture surgery, can keep another hip from breaking.
Austria · Belgium · Canada - recruiting
Primary Care Management of Osteoporosis in Older Women
This study aims to improve how older women with osteoporosis are cared for by their local doctors and nurses. Researchers want to understand what works well and what doesn't, by talking to women and health professionals. The goal is to create better guidelines and support for managing osteoporosis.
United Kingdom - recruiting
The Osteoporotic Fracture Classification-based Scoring System for Treatment Decision in Thoracolumbar Osteoporotic Fractures
This study looks at how a new scoring system helps doctors decide the best treatment for broken bones in the back caused by osteoporosis. It compares how well patients do when doctors follow the score's advice versus when they choose a different path.
United States · Argentina · Brazil - recruiting
OSTEOMICS: Identifying Regulators of Bone Homeostasis
This study, OSTEOMICS, is looking at bone diseases like osteoporosis and osteoarthritis. We're collecting bone samples from patients having orthopaedic surgery to understand bone health better and find new ways to treat these common conditions.
United Kingdom - ongoing, recruitingTherapeutic exploratory (Phase II)
Senolytics to Improve Osteoporosis therapy: A randomised controlled clinical trial The SENIOR Trial
This study, called THE SENIOR Trial, is looking into a new treatment for weak bones (osteopenia and osteoporosis). It investigates if a medicine called DASATINIB can improve bone health by slowing down bone breakdown. We're measuring changes in a blood marker of bone breakdown after 21 weeks.
Denmark - ongoing, recruitingTherapeutic confirmatory (Phase III)
A Randomized, Double-blind, Parallel-group, Active-controlled Study to Compare the Efficacy, Pharmacokinetics, Pharmacodynamics, Safety, and Immunogenicity of MAB-22 Versus Prolia® Sourced from the European Union in Postmenopausal Women with Osteoporosis
This study compares a new medicine called MAB-22 with an existing one, Prolia, for postmenopausal women with osteoporosis. It checks how well they build bone, how the body handles them, and if they are safe. It's to confirm if MAB-22 is a good alternative.
Czechia · Bulgaria · Poland - active not recruitingNA
Resistance Exercise Training to Improve Bone and Articular Cartilage Health in Women
This study looks at how different types of exercise can help strengthen bones and protect joints in women aged 50-70. It compares two exercise programs to see which is best for conditions like weak bones (osteoporosis) and joint wear (osteoarthritis).
United Kingdom - not yet recruiting
The Oswestry Metabolic BONE Cohort
This study looks at how conditions like osteoporosis, obesity, and diabetes affect bone health and fracture risk. Researchers use information from regular patient care, including scans and health records, to better understand and predict broken bones, helping improve treatments.
United Kingdom - authorisedTherapeutic exploratory (Phase II)
Influence Of Zoledronic Acid On Healing After Arthroskopic Repair Of Chronic Rotator Cuff Lesions A Prospective, Randomized, Placebo-Controlled Phase II Trial ZORRO
This study, called ZORRO, is looking at whether a medicine called zoledronic acid can help shoulder tendons heal better after keyhole surgery for a tear. We want to see if it stops the tear from coming back in people with tendon problems or weak bones.
Austria - recruiting
Gut microbial activity, lifestyle factors, and bone metabolism in premenopausal and postmenopausal women
This study looks at how gut bacteria, diet, and exercise link to bone health in women before and after menopause. We want to see if changes in these areas affect bone strength as women get older.
United Kingdom · England