- recruitingTherapeutic confirmatory (Phase III)
A Randomized, Double-blind, Parallel-group, Active-controlled Study to Compare the Efficacy, Pharmacokinetics, Pharmacodynamics, Safety, and Immunogenicity of MAB-22 Versus Prolia® Sourced from the European Union in Postmenopausal Women with Osteoporosis
This study compares a new medicine called MAB-22 with an existing one, Prolia, for postmenopausal women with osteoporosis. It checks how well they build bone, how the body handles them, and if they are safe. It's to confirm if MAB-22 is a good alternative.
Czechia · Bulgaria · Poland - recruiting
Gut microbial activity, lifestyle factors, and bone metabolism in premenopausal and postmenopausal women
This study looks at how gut bacteria, diet, and exercise link to bone health in women before and after menopause. We want to see if changes in these areas affect bone strength as women get older.
United Kingdom · England - recruitingNA
People With Osteoporosis Can Walk-BEST to Reduce Fall and Fracture Risk
This study looks at whether a special walking program, Walk-BEST™, can help older people with osteoporosis improve their balance and walking. It uses a small sensor and guided practice to help reduce the risk of falls and broken bones.
Canada - recruiting
The Impact of Hormonal Contraceptive Use and Lifestyle Factors on Fracture Risk and Bone Quality in Young Female Adults
This study looks at how birth control and lifestyle affect bone health in young women in the German armed forces. Researchers want to understand if different contraceptives, exercise, diet, and other factors impact bone strength and reduce the risk of breaks.
Germany - recruiting
Primary Care Management of Osteoporosis in Older Women
This study aims to improve how older women with osteoporosis are cared for by their local doctors and nurses. Researchers want to understand what works well and what doesn't, by talking to women and health professionals. The goal is to create better guidelines and support for managing osteoporosis.
United Kingdom - recruitingNA
Cardiovascular Risk in Digital Osteoarthritis
This study looks at the link between osteoarthritis in the finger joints and heart health. Researchers will compare people with finger osteoarthritis to people without, checking their heart risk using special scans and health checks to understand this connection better.
France - recruiting
Biobank for Inflammatory Chronic Diseases and Osteoporosis
This study aims to create a collection of blood samples from people with certain types of arthritis (rheumatoid, psoriatic, spondyloarthritis) or osteoporosis. Researchers hope to find markers in the blood that can help doctors choose the best treatments for these conditions.
France - active not recruitingNA
Clinical Study to Predict the Risk of Bone Fractures With the POROUS Ultrasound Device
This study looks at a new ultrasound scanner, called POROUS, to see if it can better predict bone breaks, especially in older adults. It compares POROUS with the usual X-ray scan (DXA) to help improve how we find and treat weak bones.
Austria · Germany · Netherlands - enrolling by invitation
Longitudinal Evaluation of a Fracture Liaison Service
This study looks at a service for people who've broken a bone due to a fall, checking how many have brittle bones (osteoporosis). It also examines if treatments are being used, if new breaks occur, and what puts people at risk, aiming to improve bone health care.
France - recruiting
Self-questionnaire in Osteoporosis
This study looks at a new questionnaire to help spot rare bone conditions in people with osteoporosis. It compares answers from the questionnaire to family history details collected over the phone, hoping to make early detection better for those at risk.
Canada - recruitingNA
Dairy vs Plant-based Beverages for Improving Bone Health During Exercise
This study looks at how different drinks affect bones in older adults doing exercise. We compare dairy milk, a pea drink, and an almond drink after strength training to see which helps bones, muscles, and overall fitness best in men and women over 50.
Canada - recruitingNA
The PREVENT Trial: a Pragmatic Cluster Randomized Controlled Trial of a Multifaceted Fracture Prevention Model for Long-term Care
This study looks at a new programme called PREVENT designed to lower the risk of hip fractures in older people living in care homes. It will compare care homes using the PREVENT programme with those providing usual care to see if hip fractures become less common.
Canada - recruiting
The Osteoporotic Fracture Classification-based Scoring System for Treatment Decision in Thoracolumbar Osteoporotic Fractures
This study looks at how a new scoring system helps doctors decide the best treatment for broken bones in the back caused by osteoporosis. It compares how well patients do when doctors follow the score's advice versus when they choose a different path.
United States · Argentina · Brazil - recruiting
OSTEOMICS: Identifying Regulators of Bone Homeostasis
This study, OSTEOMICS, is looking at bone diseases like osteoporosis and osteoarthritis. We're collecting bone samples from patients having orthopaedic surgery to understand bone health better and find new ways to treat these common conditions.
United Kingdom - active not recruitingNA
Resistance Exercise Training to Improve Bone and Articular Cartilage Health in Women
This study looks at how different types of exercise can help strengthen bones and protect joints in women aged 50-70. It compares two exercise programs to see which is best for conditions like weak bones (osteoporosis) and joint wear (osteoarthritis).
United Kingdom - not yet recruiting
The Oswestry Metabolic BONE Cohort
This study looks at how conditions like osteoporosis, obesity, and diabetes affect bone health and fracture risk. Researchers use information from regular patient care, including scans and health records, to better understand and predict broken bones, helping improve treatments.
United Kingdom - recruitingNA
RESTORE - Study of AGN1 LOEP to Prevent Secondary Hip Fractures
This study, called RESTORE, looks at a new treatment (AGN1 LOEP) to help prevent a second hip fracture in older women who have already had one. Researchers want to see if this treatment, given after the first hip fracture surgery, can keep another hip from breaking.
Austria · Belgium · Canada