RecruitingOBSERVATIONAL

Biobank for Inflammatory Chronic Diseases and Osteoporosis

This study is building a collection, called a biobank, of blood samples from patients treated at the Rheumatology center of Toulouse University Hospital. They are focusing on people with chronic inflammatory conditions like rheumatoid arthritis, psoriatic arthritis, and spondyloarthritis, as well as those with osteoporosis. The main goal is to discover 'biomarkers' – specific signs in the blood – that can predict how well a patient will respond to certain medicines. For conditions like arthritis, this could help doctors pick the most effective treatment from the beginning. For osteoporosis, it aims to help doctors decide the best treatment plan and understand disease severity. Ultimately, this research hopes to improve how these conditions are managed.

At a glance

Status

Recruiting

Sponsor

University Hospital, Toulouse

Enrolment target

2,000

Start

13 Sep 2021

Estimated completion

01 Sep 2031

Rheumatoid Arthritis Psoriatic Arthritis Spondyloarthritis Osteoporosis

What is this study about?

This study is about understanding how different treatments work for certain long-term conditions. Researchers are particularly interested in inflammatory types of arthritis, such as rheumatoid arthritis, psoriatic arthritis, and spondyloarthritis, as well as a bone condition called osteoporosis.

For inflammatory arthritis, there are many new medicines available. However, it's currently hard for doctors to know which treatment will be most effective for each individual patient. This study hopes to find clues in the blood (called biomarkers) that can help doctors make better, more personalised choices. By collecting and storing blood samples from patients starting new treatments, they can look for patterns that link these biomarkers to how well the treatment works.

Similarly, for osteoporosis, there are various treatments, but it's not always clear which one is best for each person. By studying blood samples from patients with osteoporosis, the researchers aim to discover biomarkers that can predict how severe the condition might become or how well a treatment will work. This could lead to more effective treatment plans and better outcomes for patients in the future.

Key takeaways

This study collects blood samples to help improve treatments for certain types of arthritis and osteoporosis.
It aims to find clues in the blood (biomarkers) that predict how well treatments work.
Participation mainly involves giving blood during your regular hospital visits.
It's for adults aged 18-99 with specific arthritis types or osteoporosis, covered by NHS.
Helping future patients is the main benefit; there are no direct personal medical benefits.
You can withdraw from the study at any time.

Who may be eligible?

To join this study, you must be an adult aged between 18 and 99 years old. You need to have been diagnosed with a chronic inflammatory type of arthritis, such as rheumatoid arthritis, psoriatic arthritis, or spondyloarthritis, or you must have osteoporosis. You also need to be a part of the UK's National Health Assurance system.

It's very important that you are able to understand what the study involves and provide your clear permission (consent) to take part.

However, some people cannot participate. This includes if you are pregnant or breastfeeding, if you are unable to give consent for any reason, or if you have severe anaemia (a very low red blood cell count).

Could this study suit you?

Answer these quick questions to see if you may be eligible. This is a guide only — the research team makes the final call.

Are you 18 to 99 years old?
Do you have rheumatoid arthritis, psoriatic arthritis, spondyloarthritis, or osteoporosis?
Do you have National Health Assurance?
Are you able to understand the study and agree to take part?
Are you currently not pregnant or breastfeeding?
Do you not have severe anaemia?

Answer every question to see your result.

What does participation involve?

If you decide to take part in this study, it's quite simple. Your involvement mainly includes providing blood samples. These samples will be collected during your regular visits to the Rheumatology centre at Toulouse University Hospital. There will be no extra hospital visits just for the study; it will fit in with your existing appointments. The researchers will then store these samples to look for important information, or 'biomarkers', in your blood. This is a long-term project to understand these conditions better, but your direct involvement will be limited to these blood sample collections.

Potential risks and benefits

The main benefit of taking part is that your contribution will help researchers understand these conditions better, potentially leading to improved treatments for future patients. There are no direct personal medical benefits to you from participating. The main risk involved is the minor discomfort, bruising, or a small chance of infection associated with having a blood sample taken, similar to routine blood tests. You are free to withdraw from the study at any time without giving a reason, and this will not affect your medical care.

Locations (1)

Purpan University Hospital
Verified postcode
Toulouse, France· Recruiting

Common questions

What is a 'biobank'?

A biobank is like a special library that stores biological samples, such as blood or tissue, for research purposes. In this study, it's a collection of blood samples.

What are 'biomarkers'?

Biomarkers are signs that can be found in your blood or body that might tell us something about a disease, how severe it is, or how well a treatment might work.

Will I get any results from my blood samples?

No, you will not receive personal results from the tests done on your samples. The research aims to find general patterns, not to provide individual medical advice.

How long will my blood samples be stored?

Your blood samples will be stored for a long time, potentially many years, so researchers can continue to study them as new technologies and ideas emerge.

Who will have access to my samples and information?

Only authorised researchers involved in this study will have access to your samples and information. Your personal details will be kept private and confidential.

How to find out more

Adeline RUYSSEN-WITRAND, MD

ruyssen-witrand.a@chu-toulouse.fr 561775626 Official trial record

Always speak to your GP or specialist before deciding to take part in a study.