Chronic Total Occlusion of Coronary Artery research hub
35 indexed studies · 26 currently recruiting
- active not recruitingNA
Invest-CTO PCI Trial
This study looks at a new two-step procedure for serious blockages in heart arteries called CTOs. Doctors want to see if planning two shorter procedures, instead of one long one, is safer, works better, and is a better experience for patients.
United States · Norway · United Kingdom - recruiting
IMMUNO-FIT Observational Study
This study looks at how immunotherapy for cancer affects your fitness, quality of life, and side effects. We want to see if being fitter helps you cope better and understand how your fitness changes during treatment. It's an observation study, so your cancer treatment won't change.
United Kingdom - active not recruiting
Profiling Microbiome Associated Metabolic Pathways in Oesophageal Cancer Survivors
This study looks at how gut germs affect long-term health in people who've had gullet cancer surgery. We're hoping to find new ways to spot and treat gut problems to improve their quality of life after cancer.
United Kingdom - active not recruitingPHASE2
Artificial Intelligence Supporting CAncer Patients Across Europe - the ASCAPE Project
This study uses AI to improve life quality for breast and prostate cancer patients across Europe. It aims to create personalised predictions about challenges patients might face and suggest ways doctors can help, using smart technology and data.
Greece · Spain · Sweden - active not recruiting
Measuring and Mapping Cognitive Decline After Brain Radiosurgery
This study looks at how focused brain radiation (SRS) affects brain function and quality of life in people with brain tumours. Researchers want to find out which brain areas are most affected so they can improve future treatments and reduce side effects.
United Kingdom - recruitingNA
Impact of a Novel Functional Snack on Perimenopausal Symptoms and Well-being
This study looks at whether a special snack can help women aged 40-55 going through perimenopause. It aims to see if the snack improves symptoms like hot flushes, mood, and sleep, and how it might affect gut health.
United Kingdom - recruiting
The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study
The MOMENTUM Study is tracking how a new type of advanced radiotherapy, called MR-Linac, works for people with different cancers. It aims to see if this treatment improves survival, controls cancer better, and enhances quality of life by using highly precise radiation guidance.
United States · Australia · Belgium - recruiting
Routine Evaluation of People Living With Cancer
This study looks at how incurable cancer affects people's bodies and daily lives. We want to understand common problems like weight loss, tiredness, and how cancer affects their bodies. This will help doctors plan better care and future treatments for people like you.
United Kingdom - recruitingNA
Dietary Supplements and Middle Aged Women (Collagen & Omega)
This study looks at how collagen and omega-3 supplements might affect middle-aged women's health. Researchers will check things like joint pain, energy levels, sleep, and overall well-being. Participants will take the supplements or a dummy pill for 8 weeks.
United Kingdom - recruitingNA
Dietary Supplements and Middle Aged Women (Creatine)
This study looks at how a common food supplement, creatine, affects health in women aged 35-65. It's exploring areas like energy, muscle strength, sleep, and joint pain over 8 weeks to see if it makes a difference.
United Kingdom - recruitingNA
The Use of Cannabidiol Suppositories for Sexual Pain
This study looks at whether CBD suppositories can reduce sexual pain and improve overall well-being. We want to see if different doses of CBD help people feel better during intimacy. If it works, we hope to study it on a larger scale.
United Kingdom - not yet recruiting
Ultrahypofractionated, Adaptive Radiation Therapy of Prostate Cancer
This study looks at a new way to give radiation treatment for prostate cancer, called ultrahypofractionated radiotherapy. It uses a smart machine to adjust treatment daily, aiming to be gentler and improve quality of life.
Germany - recruitingNA
Improved Muscle Metabolism by Combination of Muscle Activation and Protein Substitution ( IMEMPRO )
This study looks at how combining extra protein with early exercise and muscle stimulation helps critically ill patients in intensive care. The aim is to reduce muscle weakness that often develops during their stay and improve their long-term recovery.
Austria · Germany - active not recruitingNA
Assessment of the Effects of Maela Connected Follow-up on Well-being and Pain After Lumbar Spine Surgery
This study looks at how a special app could help people recover from back surgery. We want to see if using the app after lumbar spine surgery helps with pain and makes life better compared to standard care. Only adults aged 18 to 60 having their first back surgery can take part.
France - not yet recruiting
Quality of Life Improvement After TAVI (QualiTAVI-UK Trial)
This UK study looks at how a heart procedure called TAVI improves quality of life. It checks both physical and mental well-being in patients receiving a new heart valve, aiming to understand the long-term benefits.
United Kingdom - recruiting
Registry for Hypoparathyroidism Wuerzburg
This study looks at how hypoparathyroidism and its long-term treatment affect people's health, daily life, and overall well-being. Researchers want to understand problems like low or high calcium, and how people are feeling, using interviews and tests like blood samples and scans.
Germany - recruitingNA
Improving Patient Reported Outcome Measures in Catheter Ablation
This study looks at how tracking patients' own reports of their health and quality of life can help us better understand a heart procedure called catheter ablation for a fast heartbeat (VT). It aims to see if more frequent check-ins improve how we measure the treatment's success.
United Kingdom - active not recruiting
One-year Outcomes in Survivors of the Severe COVID-19 Pneumonia (CO-Qo-ICU)
This study looks at how people who had severe COVID-19 and were in intensive care are doing one year later. Researchers want to understand their physical health, mental wellbeing, and how it affects their daily lives, including getting back to work.
France - recruiting
Prospective Observational Trial to Evaluate Quality of Life After Definitive Chemoradiation in Patients With Anal Cancer (LANACARE)
This study looks at how quality of life changes for people with anal cancer receiving a treatment called chemoradiation. Researchers will use questionnaires to understand how patients feel, how well their body works, and how successful the treatment is over time.
Germany - not yet recruiting
Screening for Cognitive Disorders in Multiple Sclerosis
This study looks at how MS affects memory and thinking skills. We will use simple tests to see if people with MS have these difficulties and how it impacts their daily lives. The aim is to better understand these challenges in adults with MS.
France - not yet recruitingNA
Impact of Ambulatory Management for Primary Spontaneous Pneumothorax in the Emergency Department on Quality of Life
This study looks at treating a collapsed lung (primary spontaneous pneumothorax) at home for some patients, instead of in the hospital. Researchers want to see if this improves quality of life compared to standard hospital care and if it's an effective way to manage the condition.
France - recruiting
Quality of Life in Patients Having a Prosthetic Joint Infection
This study looks at the quality of life for people with an infection in an artificial joint. It uses questionnaires to understand how these infections affect daily life. The aim is to gather important information that can help improve care for patients in the future.
France - recruiting
Medical Affairs Pharmaceutical Physician Work-related Quality of Life (MAPPWrQoL) Instrument Development and Patient Registry (MAPPWrQoLReg)
This study looks at how work affects the well-being of doctors who work in pharmaceutical companies. It aims to create a new way to measure their quality of life, focusing on work-related factors like stress. Participants will help develop and then use this tool over a year.
United Kingdom - recruitingNA
Effects of a Collagen Supplement on Quality of Life, Appetite and Glycaemic Control
This study looks at whether a collagen supplement can improve quality of life, appetite, and blood sugar levels in adults who are overweight or obese. We want to see if it helps with things like energy, mood, and sleep over eight days.
United Kingdom - recruitingNA
Quality of Life Related to Different Treatment Protocols for Post-thyroidectomy Hypoparathyroidism
This study compares two ways to give medicine after thyroid surgery to prevent low calcium. It looks at how each method affects patients' quality of life. Doctors want to find out which approach works best for patients.
Canada - active not recruiting
Support and Post-therapeutic Rehabilitation for Women in Complete Remission of Breast Cancer in a Thermal Environment
This study looks at how a 3-week spa treatment helps women who have finished breast cancer treatment. It aims to see if this special program improves their quality of life over time, focusing on feelings of well-being and recovery after cancer.
France - recruiting
Translation and Validation of the MQOL Self-questionnaire Into French for Assessing Quality of Life in Patients With Meningiomas
This study aims to create a French version of a questionnaire called MQOL. This questionnaire helps understand how meningioma brain tumours affect a person's daily life. It will then be tested with 50 patients to make sure it works well.
France - not yet recruiting
Study on the Prevention of Recidivism and the Consequences of Sexual Violence Suffered by Female Asylum Seekers in France
This study looks at how best to support women seeking asylum in France who have experienced sexual violence. It compares standard care with a new, organised support system to see if it helps prevent further violence and improves health and well-being.
France - recruiting
Evaluation of the Epilepsy-related Quality of Life, Seizure-related Accidents and Validation of the Mjn-SERAS Solution in the Normalised Patient Environment with Real-World Data
This study is testing a medical device called mjn-SERAS, designed to detect epileptic seizures early and give a warning. It's for people aged 12-65 in the UK, Spain, and Germany who have epilepsy that hasn't responded well to medication. The aim is to see if using the device improves their daily life.
Germany · Spain · United Kingdom - active not recruiting
Spasmodic Dysphonia Interviews
This study wants to talk to people with Spasmodic Dysphonia, a voice condition, to understand how it affects their daily lives, work, and social activities. Researchers will ask about their experiences, including how botulinum toxin injections help them.
United Kingdom - active not recruitingNA
ABC - A Post Intensive Care Anaemia Management Trial
This study looks at treating anaemia (low red blood cells) in patients after intensive care. It compares standard care with a more active approach to see if it helps patients recover better and feel less tired after leaving ICU.
United Kingdom - recruiting
Reconstruction in Extended MArgin Cancer Surgery
This study looks at different ways to help patients recover after major surgery for advanced pelvic cancer. It aims to find the best methods to reduce problems and improve quality of life using information from hospital records, surveys, and patient interviews.
United Kingdom - recruiting
European Multicentre Registry of Percutaneous Paravalvular Leak Closure
This study looks at a keyhole procedure to fix leaky heart valves. We want to see how well it works, how safe it is, and if it improves patients' lives. It's for people aged 16 and over needing this specific treatment.
Belgium · Czechia · France - recruiting
Clinical Outcomes From Treatment and Evaluation of Obstructive Sleep Apnoea in Children With Down Syndrome
This study looks at how a breathing machine called non-invasive ventilation helps children with Down Syndrome who have sleep apnoea. It aims to understand how this treatment affects their well-being, daily behaviour, and what challenges families face when using it.
Ireland · United Kingdom - recruiting
Pain AND Opioids After Surgery
This study looks at how painkillers called opioids are used by people having surgery in the UK and Europe. It aims to understand how opioid use might affect pain, recovery, and quality of life after an operation.
Croatia · United Kingdom