Chronic Total Occlusion of Coronary Artery research hub
21 indexed studies · 14 currently recruiting
- active not recruitingNA
Invest-CTO PCI Trial
This study looks at a new two-step procedure for serious blockages in heart arteries called CTOs. Doctors want to see if planning two shorter procedures, instead of one long one, is safer, works better, and is a better experience for patients.
United States · Norway · United Kingdom - recruiting
The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study
The MOMENTUM Study is tracking how a new type of advanced radiotherapy, called MR-Linac, works for people with different cancers. It aims to see if this treatment improves survival, controls cancer better, and enhances quality of life by using highly precise radiation guidance.
United States · Australia · Belgium - recruitingNA
The Use of Cannabidiol Suppositories for Sexual Pain
This study looks at whether CBD suppositories can reduce sexual pain and improve overall well-being. We want to see if different doses of CBD help people feel better during intimacy. If it works, we hope to study it on a larger scale.
United Kingdom - active not recruiting
Spasmodic Dysphonia Interviews
This study wants to talk to people with Spasmodic Dysphonia, a voice condition, to understand how it affects their daily lives, work, and social activities. Researchers will ask about their experiences, including how botulinum toxin injections help them.
United Kingdom - recruitingNA
Effects of a Collagen Supplement on Quality of Life, Appetite and Glycaemic Control
This study looks at whether a collagen supplement can improve quality of life, appetite, and blood sugar levels in adults who are overweight or obese. We want to see if it helps with things like energy, mood, and sleep over eight days.
United Kingdom - recruiting
Routine Evaluation of People Living With Cancer
This study looks at how incurable cancer affects people's bodies and daily lives. We want to understand common problems like weight loss, tiredness, and how cancer affects their bodies. This will help doctors plan better care and future treatments for people like you.
United Kingdom - recruiting
European Multicentre Registry of Percutaneous Paravalvular Leak Closure
This study looks at a keyhole procedure to fix leaky heart valves. We want to see how well it works, how safe it is, and if it improves patients' lives. It's for people aged 16 and over needing this specific treatment.
Belgium · Czechia · France - recruiting
Clinical Outcomes From Treatment and Evaluation of Obstructive Sleep Apnoea in Children With Down Syndrome
This study looks at how a breathing machine called non-invasive ventilation helps children with Down Syndrome who have sleep apnoea. It aims to understand how this treatment affects their well-being, daily behaviour, and what challenges families face when using it.
Ireland · United Kingdom - active not recruiting
Measuring and Mapping Cognitive Decline After Brain Radiosurgery
This study looks at how focused brain radiation (SRS) affects brain function and quality of life in people with brain tumours. Researchers want to find out which brain areas are most affected so they can improve future treatments and reduce side effects.
United Kingdom - recruitingNA
Improving Patient Reported Outcome Measures in Catheter Ablation
This study looks at how tracking patients' own reports of their health and quality of life can help us better understand a heart procedure called catheter ablation for a fast heartbeat (VT). It aims to see if more frequent check-ins improve how we measure the treatment's success.
United Kingdom - recruitingNA
Impact of a Novel Functional Snack on Perimenopausal Symptoms and Well-being
This study looks at whether a special snack can help women aged 40-55 going through perimenopause. It aims to see if the snack improves symptoms like hot flushes, mood, and sleep, and how it might affect gut health.
United Kingdom - not yet recruiting
Quality of Life Improvement After TAVI (QualiTAVI-UK Trial)
This UK study looks at how a heart procedure called TAVI improves quality of life. It checks both physical and mental well-being in patients receiving a new heart valve, aiming to understand the long-term benefits.
United Kingdom - active not recruiting
Profiling Microbiome Associated Metabolic Pathways in Oesophageal Cancer Survivors
This study looks at how gut germs affect long-term health in people who've had gullet cancer surgery. We're hoping to find new ways to spot and treat gut problems to improve their quality of life after cancer.
United Kingdom - active not recruitingNA
ABC - A Post Intensive Care Anaemia Management Trial
This study looks at treating anaemia (low red blood cells) in patients after intensive care. It compares standard care with a more active approach to see if it helps patients recover better and feel less tired after leaving ICU.
United Kingdom - recruiting
Medical Affairs Pharmaceutical Physician Work-related Quality of Life (MAPPWrQoL) Instrument Development and Patient Registry (MAPPWrQoLReg)
This study looks at how work affects the well-being of doctors who work in pharmaceutical companies. It aims to create a new way to measure their quality of life, focusing on work-related factors like stress. Participants will help develop and then use this tool over a year.
United Kingdom - ongoing, recruitingTherapeutic exploratory (Phase II)
Improvement of Quality of Life by Cannabinoids in Oncologic Patients (BELCANTO)
This study is testing if cannabis extract can improve the quality of life for cancer patients receiving palliative care. It compares the cannabis extract to a placebo to see if it helps with symptoms and overall well-being over approximately 12 days.
Germany - recruiting
Pain AND Opioids After Surgery
This study looks at how painkillers called opioids are used by people having surgery in the UK and Europe. It aims to understand how opioid use might affect pain, recovery, and quality of life after an operation.
Croatia · United Kingdom - recruiting
Reconstruction in Extended MArgin Cancer Surgery
This study looks at different ways to help patients recover after major surgery for advanced pelvic cancer. It aims to find the best methods to reduce problems and improve quality of life using information from hospital records, surveys, and patient interviews.
United Kingdom - active not recruitingPHASE2
Artificial Intelligence Supporting CAncer Patients Across Europe - the ASCAPE Project
This study uses AI to improve life quality for breast and prostate cancer patients across Europe. It aims to create personalised predictions about challenges patients might face and suggest ways doctors can help, using smart technology and data.
Greece · Spain · Sweden - recruiting
Evaluation of the Epilepsy-related Quality of Life, Seizure-related Accidents and Validation of the Mjn-SERAS Solution in the Normalised Patient Environment with Real-World Data
This study is testing a medical device called mjn-SERAS, designed to detect epileptic seizures early and give a warning. It's for people aged 12-65 in the UK, Spain, and Germany who have epilepsy that hasn't responded well to medication. The aim is to see if using the device improves their daily life.
Germany · Spain · United Kingdom - recruiting
IMMUNO-FIT Observational Study
This study looks at how immunotherapy for cancer affects your fitness, quality of life, and side effects. We want to see if being fitter helps you cope better and understand how your fitness changes during treatment. It's an observation study, so your cancer treatment won't change.
United Kingdom