- recruitingPhase II and Phase III (Integrated)
C4671026-A PHASE 2/3, INTERVENTIONAL SAFETY, PHARMACOKINETICS, AND EFFICACY, OPEN-LABEL, MULTI-CENTER, SINGLE-ARM STUDY TO INVESTIGATE ORALLY ADMINISTERED PF-07321332 (NIRMATRELVIR)/RITONAVIR IN NONHOSPITALIZED SYMPTOMATIC PEDIATRIC PARTICIPANTS WITH COVID-19 WHO ARE AT RISK OF PROGRESSION TO SEVERE DISEASE
This study looks at an antiviral medicine (nirmatrelvir and ritonavir) for children and young people with COVID-19. Researchers want to find out how safe the medicine is, how the body handles it, and whether it stops mild COVID-19 from turning into severe illness in vulnerable young patients.
Bulgaria · Hungary - recruitingTherapeutic use (Phase IV)
A Phase 4 Pragmatic, Randomized Trial to Evaluate the Effectiveness and Safety of mRNA-1273 Variant-Containing Vaccine Formulation Against Severe Outcomes in Adults Aged 50-64 Years Without Risk Factors for Severe COVID-19 (DAN-COVID)
This study looks at how well an updated Moderna COVID-19 booster jab (Spikevax) protects healthy adults. Researchers want to see if the vaccine prevents severe illness, visits to the doctor, and hospital stays in people aged 50 to 64 who do not have other high-risk health conditions.
Denmark - recruitingTherapeutic use (Phase IV)
TURN-COVID Biobank: The Dutch cohort study tor the evaluation of the use of neutralizing monoclonal antibodies and other antiviral agents against SARS-CoV-2
This study looks at how well certain COVID-19 treatments work, such as Ronapreve, Evusheld, Xevudy, and Paxlovid. It’s also building a collection of samples to help understand these treatments and new ones in the future. The study is for adults with COVID-19.
Netherlands - recruitingTherapeutic exploratory (Phase II)
Open-label, Multi-centre, Non-Inferiority study of safety and immunogenicity of BIMERVAX as heterologous booster for the prevention of coronavirus disease 2019 (COVID-19) in adolescents from 12 years to less than 18 years of age.
This study is looking at a new COVID-19 booster vaccine called BIMERVAX for teenagers aged 12 to 17. It aims to see if BIMERVAX is as safe and effective as another vaccine, HIPRA-HH-2, in boosting protection against the Omicron variant of COVID-19.
Spain - recruiting
COVID-19: Early Detection of Worsening by Voice and Respiratory Pattern Characteristics
This study looks at whether we can use a phone app to spot early signs of COVID-19 getting worse. It uses your voice and breathing sounds to predict if someone might need intensive care, helping hospitals prepare.
France - recruitingNA
Olfactory Training As a Treatment for Olfactory Dysfunction Post COVID-19
This study looks at how "smell training" can help people whose sense of smell changed after COVID-19. We're comparing two different sets of smells to see which works best to bring back normal smelling.
Canada - active not recruitingPHASE1
COVID-19 Omicron BA.5 Subvariant Dose Finding Infection Study
Researchers are studying how much of the Omicron BA.5 virus causes infection in people who've had COVID-19 vaccines or infections before. This helps them understand the virus better and test treatments more safely, helping to protect people from getting very sick from future COVID-19 variants.
United Kingdom - active not recruitingPHASE2, PHASE3
Study of a Recombinant Coronavirus-Like Particle COVID-19 Vaccine in Adults
This study is testing a new COVID-19 vaccine to see how well it works and if it's safe. It's for adults aged 18 and over and involves injections and monitoring over time.
United States · Argentina · Brazil