- recruiting
Real-World Study of Patients With Type 1 Diabetes Treated With Teplizumab as Part of Managed Access Programs (MAPs)
This study looks back at people in the UK and other countries who received a treatment called teplizumab for Type 1 diabetes through special early access schemes. It aims to understand how the treatment was used and the characteristics of the patients.
Belgium · France · Italy - active not recruitingNA
Targeted Assessment in High-Risk paTients With dIAbetes to ideNtify Undiagnosed Heart Failure
This study looks at a new way to find hidden heart failure in people with diabetes who are at higher risk. We're testing if checking a specific blood marker helps doctors discover heart problems earlier, so people can get the right care sooner.
United Kingdom - recruitingPHASE2
Sotagliflozin in Patients With Heart Failure Symptoms and Type 1 Diabetes
This study looks at whether a tablet called sotagliflozin can help people with type 1 diabetes and heart failure feel better. We're testing if it improves their quality of life and is safe, compared to a dummy pill.
United Kingdom - active not recruitingPHASE1, PHASE2
A Safety, Tolerability, and Efficacy Study of VX-264 in Participants With Type 1 Diabetes
This study is looking at a new medicine called VX-264 for people with Type 1 Diabetes. We want to see if it's safe, how well people tolerate it, and if it helps manage the condition. It's for adults aged 18-65.
United States · Canada · Germany - not yet recruitingNA
UK MyREMEDY Clinical Trial
The UK MyREMEDY study is looking at an online program called MyDiaMate. It aims to help adults in the UK with type 1 diabetes better manage the emotional challenges of their condition. Researchers want to see if MyDiaMate improves mental health compared to usual care.
United Kingdom - active not recruitingNA
MyDiaMate For Remission Of Diabetes Distress In Type 1 Diabetes (MyREMEDY)
This study looks at whether a self-help app called MyDiaMate can improve the mental well-being of adults with Type 1 diabetes. Many people with Type 1 diabetes experience stress and worry, and this study compares using the app to regular care to see if it helps.
Germany · Netherlands · Spain - ongoing, recruitingHuman Pharmacology (Phase I)- Other
Influence of various fast-acting mealtime insulin preparations in individuals with type 1 diabetes, with slow, moderate, and rapid gastric emptying, on postprandial blood glucose and the formation of reactive oxygen species
This study looks at how different fast-acting insulins affect blood sugar levels after meals in people with Type 1 diabetes. It compares insulins like Lyumjev and Humalog to see which works best depending on how quickly food leaves the stomach.
Germany - recruitingPHASE2
SAFety and Efficacy of Human Anti-thymocyte ImmunoGlobUlin SAB-142 ARresting Progression of Type 1 Diabetes
This study is testing a new drug, SAB-142, for people with recently diagnosed Type 1 Diabetes. It aims to see if SAB-142 can slow down the disease, and if it's safe to use. Participants will receive high dose, low dose, or a dummy drug.
United States · Australia · Austria