- ongoing, recruitingHuman Pharmacology (Phase I)- Other
A Study to Learn How Different Manufactured Products of the Study Medicine Called Ritlecitinib are Taken up Into the Blood in Healthy Adults When Taken on an Empty Stomach or When Taken With a Meal in Healthy Adults.
This study looks at how a new medicine, ritlecitinib, gets into the blood of healthy adults. We're testing different versions of the medicine, both when taken on an empty stomach and with food. It could help people with conditions like ulcerative colitis or alopecia.
Belgium - active not recruitingPHASE3
A Study to Compare the Efficacy and Safety of SCENESSE and Narrow-Band Ultraviolet (NB-UVB) Light Versus NB-UVB Light Alone in Patients With Vitiligo
This study looks at a new treatment for vitiligo, a condition where patches of skin lose their colour. It compares a special implant (afamelanotide) combined with light therapy (NB-UVB) against light therapy alone, to see how well they work and if they are safe.
United States · France · Kenya - not yet recruiting
Vitiligo Registry for Adults and Children in the UK
This study is gathering information on people in the UK with vitiligo, both adults and children. It's creating a big database to better understand the condition, how treatments work, and how safe they are, as there isn't one like this right now.
United Kingdom - active not recruitingPHASE3
A 52-Week Study to Learn About the Safety and Effects of Ritlecitinib in Participants With Nonsegmental Vitiligo
This study looks at a medicine called ritlecitinib for non-segmental vitiligo, a skin condition causing white patches. It checks how safe and effective the medicine is and if it keeps working or helps more. People who were in an earlier study can join this one.
United States · Australia · Bulgaria - authorisedTherapeutic exploratory (Phase II)
“A phase 2 multi-center study investigating the efficacy, safety and tolerability of pioglitazone in adult participants with non-segmental vitiligo”
This study is looking into a new use for an existing medicine called pioglitazone for adults with vitiligo. We want to see if this tablet can help improve skin colour and is safe to use. This is an early-stage study to understand its effects better.
Italy - authorisedTherapeutic exploratory (Phase II)
MitOxyVit: Mitochondrial network modulation approach using hyperbaric oxygen (HBO) therapy and NNbUVB for treating vitiligo
This study is looking into new ways to treat vitiligo, a skin condition causing white patches. It combines a special oxygen therapy and light treatment. Researchers want to see if this combination can help repigment the skin and how safe it is over 24 weeks.
France - authorisedTherapeutic exploratory (Phase II)
J5D-MC-FPAD: A Phase 2a, Randomized, 24-Week, Multicenter, Double-Blind, Placebo-Controlled Proof-of-Concept Study to Investigate Efficacy and Safety of LY4005130 in Adult Participants with Non-Segmental Vitiligo
This study is testing a new medicine, LY4005130, for adults with vitiligo, a skin condition causing white patches. It aims to see if the medicine can help reduce face vitiligo and if it’s safe to use. Half the participants will get the medicine, and half a dummy treatment.
Belgium - ongoing, recruitingHuman Pharmacology (Phase I)- Other
B7981078: A PHASE 1, RANDOMIZED, OPEN-LABEL, CROSSOVER STUDY TO ESTIMATE THE RELATIVE BIOAVAILABILITY OF PEDIATRIC RITLECITINIB (PF-06651600) SPRINKLED IN APPLESAUCE, YOGHURT AND STRAWBERRY JAM RELATIVE TO INTACT BLEND-IN CAPSULE OF RITLECITINIB AND THE EFFECT OF FOOD ON THE BIOAVAILABILITY OF THE CAPSULE DOSAGE FORMULATION OF RITLECITNIB IN HEALTHY ADULT PARTICIPANTS
Belgium