- AuthorisedTherapeutic use (Phase IV)
Comparison of the preventive painkiller effect of etoricoxib and celecoxib after M3M surgery: A randomized, double-masked clinical trial
This study compares two pain medicines, etoricoxib and celecoxib, to see which is better at preventing pain after having a wisdom tooth (Molar 3 or M3) removed from the lower jaw. Researchers believe etoricoxib might work better.
For: postoperative period after mandibular M3 removalHungary - Ongoing, recruitingTherapeutic use (Phase IV)
Randomized trial on Spinal Anaesthesia vs. General Anaesthesia (SAGA) on recovery after total hip, total knee, and unicompartmental knee arthroplasty
This study compares two types of anaesthesia—spinal and general—for hip and knee replacement surgeries. It aims to see which one helps patients get back on their feet faster, specifically if they can walk 5 metres within 6 hours after surgery.
For: Osteoarthritis of the hip and kneeDenmark - Ongoing, recruitingTherapeutic confirmatory (Phase III)
Efficacy and Tolerability of AP707 in Patients with Chronic Back Pain
This study is looking at a new cannabis-based medicine called AP707 for people with ongoing back pain. Researchers want to see if it helps reduce pain better than a dummy treatment and how well people tolerate it.
For: Chronic back painGermany · Austria - Active not recruitingPHASE2, PHASE3
Systemic Therapy in Advancing or Metastatic Prostate Cancer: Evaluation of Drug Efficacy
This study, called STAMPEDE, looks for better ways to treat prostate cancer that is spreading or has a high chance of spreading. It tests new treatments against standard ones to help men live longer and have a better quality of life.
For: Prostate CancerSwitzerland · United Kingdom - Active not recruitingPHASE1
A Study Evaluating Safety and Tolerability, and Pharmacokinetics of Navitoclax Monotherapy and in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasm
This study looks at a new drug, navitoclax, alone or with an existing drug, ruxolitinib, for a group of blood cancers called myeloproliferative neoplasms. Researchers want to see if it's safe, how the body handles it, and if it affects other drugs.
For: Myeloproliferative NeoplasmUnited States · Belgium · Bulgaria