- AuthorisedTherapeutic confirmatory (Phase III)
Reduced anticoagulation targets in extracorporeal life support
This study looks at using lower doses of blood-thinning medicines like Heparin and Nadroparin for people on a life support machine called ECMO. It aims to see if this can reduce serious bleeding or blood clots and improve patient survival rates.
Netherlands - AuthorisedTherapeutic use (Phase IV)
PERCUTANEOUS EMBOLECTOMY, LOW DOSE THROMBOLYSIS OR HEPARIN FOR INTERMEDIATE HIGH RISK PULMONARY EMBOLISM
This study is looking at different ways to treat 'intermediate-high risk' pulmonary embolism (PE), which is a blood clot in the lungs. It compares dissolving the clot with medicine or removing it with a small procedure, to standard blood thinners. The goal is to find the best way to help people get better.
For: Pulmonary embolismDenmark - AuthorisedTherapeutic exploratory (Phase II)
PALETTE - Adaptive platform trial for personalisation of sepsis treatment in children and adults: a multi-national, treatable traits-guided, adaptive, exploratory, bayesian basket trial
This study is looking for better ways to treat sepsis in adults. It's testing several existing medicines to see if any work well for different types of sepsis. The main goals are to improve survival and help patients recover without needing machines to support their bodies.
For: SepsisFrance