Microcrystalline cellulose clinical trials
14 indexed studies · 0 currently recruiting
- Ongoing, recruitingTherapeutic confirmatory (Phase III)
Evaluation of safety and efficacy of two ticagrelorbased de-escalation antiplatelet strategies in acute coronary syndrome: the randomized, multicenter, double-blind ELECTRA RCT study.
This study looks at safer ways to give blood-thinning medicines like Brilique and Aspirin after a heart attack. It compares different doses of ticagrelor to see which causes less serious bleeding while still preventing new heart problems.
For: Acute Coronary Syndrom (ACS)Poland - AuthorisedTherapeutic confirmatory (Phase III)
Prevention of cardiac surgery-associated acute kidney injury through the use of sodium-glucose cotransporter 2 inhibitors
This study is looking at whether a drug called Jardiance can help prevent kidney problems sometimes seen after heart surgery. Researchers want to see if it can keep your kidneys working well for the first three months after your operation.
For: Cardiac-surgery associated acute kidney injurySpain - Ongoing, recruitingTherapeutic exploratory (Phase II)
A Randomized, Double-blind, Placebo-controlled, Repeat-dose, Multicenter Trial to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of HZN-825 in Patients with Diffuse Cutaneous Systemic Sclerosis [HZNP-HZN-825-301]
This study is testing a new medicine, Fipaxalparant, for people with a serious skin condition called diffuse cutaneous systemic sclerosis. It aims to see if the medicine can improve lung function and other symptoms over about a year.
For: Diffuse Cutaneous Systemic SclerosisRomania · Austria · Germany - Ongoing, recruitingPhase II and Phase III (Integrated)
Long-term aspirin therapy as a predictor of decreased susceptibility to SARSCoV-2 infection in aspirin-exacerbated respiratory disease
This study looks at whether a special treatment for people with Aspirin-Exacerbated Respiratory Disease (AERD) can reduce their risk of getting COVID-19. They're testing if taking a particular type of aspirin long-term after initial desensitisation changes how certain genes work and makes you less likely to catch the virus.
For: aspirin-exacerbated respiratory diseasePoland - Ongoing, recruitingTherapeutic exploratory (Phase II)
Evaluation de l’efficacité des alpha-bloquants (Tamsulosine) dans le traitement de la dysurie symptomatique de la sclérose en plaques chez la femme – Etude contrôlée randomisée en cross-over contre placebo.
This study is looking at how a medication called tamsulosin might help women with multiple sclerosis (MS) who have trouble urinating (peeing). Researchers want to see if it improves their symptoms over one month, compared to a dummy pill.
For: Patiente atteinte de sclérose en plaques (score EDSS < 7France - Ongoing, recruitingHuman Pharmacology (Phase I)- Other
A Multiple Ascending Dose Clinical Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of MK-7602 in Healthy Participants
This study is looking at a new medicine called MK-7602 for malaria. It's an early-stage trial to check how safe it is, if people can tolerate it well, and how the body handles the medicine in healthy volunteers. It will help us understand if it's safe to test further for malaria.
For: MalariaBelgium - Ongoing, recruitingHuman Pharmacology (Phase I)- First administration to humans
A Single Ascending Dose Clinical Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of MK-1403 in Healthy Male Participants
This early-stage study is looking at a new medicine called MK-1403 for a condition called atherosclerosis, which is a build-up in your arteries. We want to see how safe it is and how the body handles it in healthy men. It's the first time this medicine is being given to people.
For: AtherosclerosisBelgium - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of MK-0616 in Adults With Hypercholesterolemia
This study is looking at a new medicine, MK-0616, for adults with high cholesterol. It compares the new medicine to a dummy pill to see if it lowers 'bad' cholesterol and how safe it is over 24 weeks. This helps us understand if MK-0616 could be a new treatment option.
For: HypercholesterolemiaItaly · Spain · Germany - Ongoing, recruitingTherapeutic exploratory (Phase II)
A Phase 2b Randomized, Double-blind, Placebo-controlled, Repeat-dose, Multicenter Trial to Evaluate the Efficacy, Safety and Tolerability of HZN-825 in Subjects with Idiopathic Pulmonary Fibrosis
This study is testing a new medicine, Fipaxalparant, for a lung condition called Idiopathic Pulmonary Fibrosis (IPF). Researchers want to see if it's safe and helps improve lung function over one to two years compared to a dummy pill.
For: Idiopathic Pulmonary FibrosisFrance · Poland · Netherlands - Ongoing, recruitingTherapeutic exploratory (Phase II)
Efficacy and Tolerance of the Combination of Methotrexate and Phototherapy Versus Phototherapy in Adults With Progressive Vitiligo: a Randomized Doubleblind Prospective Study - METVI
This study is testing a new combination treatment for progressive vitiligo, a skin condition causing white patches. It compares light therapy alone with light therapy plus a different medicine called methotrexate. Researchers want to see if the combination works better to reduce the white patches.
For: Vitiligo with new lesions or extension of old lesions during the last 6 monthsFrance - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A MULTICENTER, PROSPECTIVE, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF SPIRONOLACTONE FOR THE TREATMENT OF ACTIVE RHEUMATOID ARTHRITIS (RA) - ALDORA
This study, called ALDORA, is looking at whether a common medicine called spironolactone could help people with rheumatoid arthritis (RA). It’s comparing spironolactone to a dummy pill to see if it reduces RA symptoms and improves heart health without causing too many side effects.
For: RHEUMATOID ARTHRITISGermany · France - Ongoing, recruitingTherapeutic confirmatory (Phase III)
VIRTUOSE: Efficiency of sildenafil on the absolute claudication distance of peripheral arterial disease patients with intermittent claudication. A phase III, National, Multicenter, Prospective, Randomized, Double-blind, Placebo-Controlled trial.
This study is testing a medicine called sildenafil to see how much it helps people with leg pain from poor circulation walk longer. It's a major study comparing the medicine to a dummy pill to find out if it's an effective treatment.
For: Peripheral arterial diseaseFrance - Ongoing, recruitingTherapeutic use (Phase IV)
Short-term effectiveness of Gabapentin versus Placebo in acute Lumbosacral Radiculalgia by herniation disc: a prospective, multicentric, randomized, controlled, double-blind study (GRADE)
This study looks at whether gabapentin helps reduce nerve pain in the lower back (lumbosacral radiculalgia) caused by a slipped disc, compared to a dummy pill (placebo). Researchers are checking pain levels after a short time.
For: lumbosacral radiculalgiaFrance - AuthorisedTherapeutic exploratory (Phase II)
Propranolol for early secondary prevention of post-traumatic stress disorder in female victims of sexual violence: a single-center, randomized, placebo-controlled pilot study - PPRESVISE
This study is looking into whether a common blood pressure medicine called propranolol might help prevent post-traumatic stress disorder (PTSD) in women who have experienced sexual violence. It's a small, early-stage study to see if this treatment could be helpful soon after a traumatic event.
For: Prevention of post-traumatic stress disorderFrance