- Active not recruitingPHASE3
To Evaluate the Efficacy and Safety of Pegozafermin in Subjects With Severe Hypertriglyceridemia
This study looks at a new drug called Pegozafermin for people with very high triglyceride levels, a type of fat in the blood. Researchers want to see if this drug can safely lower these levels over 26 weeks compared to a dummy drug.
For: Severe HypertriglyceridemiaUnited States · Argentina · Austria - RecruitingPHASE3
A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH
This study is testing a new medicine, Pegozafermin, for people with a severe liver condition called MASH with cirrhosis. It will check how well the medicine works and if it's safe compared to a dummy medicine.
For: Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated CirrhosisUnited States · Argentina · Australia - Ongoing, recruitingTherapeutic confirmatory (Phase III)
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Pegozafermin in Subjects with Severe Hypertriglyceridemia (SHTG)
This study is testing a new medicine, Pegozafermin, for people with very high triglyceride levels. We want to see if it lowers these levels and if it's safe to use. Half the participants will get the new medicine and half will get a dummy medicine.
For: Severe HypertriglyceridemiaSpain · Poland · Hungary - RecruitingPHASE3
A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)
This study is looking into a new medicine called pegozafermin for people with a liver condition called MASH, which includes scarring (fibrosis). It compares pegozafermin to a dummy medicine to see if it's safe and helps improve the liver. We want to find better ways to treat this condition.
For: Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With FibrosisUnited States · Argentina · Australia